Santiago Rayment Gomez
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View article: Molecular epidemiology of Ascaris lumbricoides following multiple rounds of community-wide treatment
Molecular epidemiology of Ascaris lumbricoides following multiple rounds of community-wide treatment Open
Control and elimination of the parasite Ascaris lumbricoides relies on mass drug administration (MDA) using a limited number of anti-helminthics. Whilst these programs have reduced the infection intensity and prevalence within many endemic…
View article: Molecular epidemiology of Ascaris lumbricoides following multiple rounds of community-wide treatment: who infects whom?
Molecular epidemiology of Ascaris lumbricoides following multiple rounds of community-wide treatment: who infects whom? Open
Control and elimination of the parasite Ascaris lumbricoides relies on mass administration using a limited number of anti-helminthics. Whilst these programs have reduced the infection intensity and prevalence within many endemic regions tr…
View article: Serological assessment of pediatric parasite exposure in two Senegalese districts using multiplex serology
Serological assessment of pediatric parasite exposure in two Senegalese districts using multiplex serology Open
Although pediatric parasitic diseases cause significant morbidity and mortality in regions with high rates of co-infection, this overlap may offer opportunities for integrated control strategies. This study aimed at a serological assessmen…
View article: Spatial heterogeneity in mass drug administration from a longitudinal epidemiological study assessing transmission interruption of soil transmitted helminths in the Wolaita zone of southern Ethiopia (Geshiyaro Project)
Spatial heterogeneity in mass drug administration from a longitudinal epidemiological study assessing transmission interruption of soil transmitted helminths in the Wolaita zone of southern Ethiopia (Geshiyaro Project) Open
Objectives Deworming programmes of soil-transmitted helminths are generally monitored and evaluated by aggregating drug coverage and infection levels at a district level. However, heterogeneity in drug coverage at finer spatial scales mean…
View article: Patterns of individual compliance with anthelmintic treatment for soil-transmitted helminth infections in southern Ethiopia over six rounds of community-wide mass drug administration
Patterns of individual compliance with anthelmintic treatment for soil-transmitted helminth infections in southern Ethiopia over six rounds of community-wide mass drug administration Open
Background The mainstay of soil-transmitted helminth (STH) control is repeated mass drug administration (MDA) of anthelmintics to endemic populations. Individual longitudinal compliance treatment patterns are important for identifying pock…
View article: Progress in controlling the transmission of schistosome parasites in Southern Ethiopia – the Geshiyaro project in the Wolaita Zone
Progress in controlling the transmission of schistosome parasites in Southern Ethiopia – the Geshiyaro project in the Wolaita Zone Open
Background This paper describes changes in the prevalence and intensity of schistosome parasite infections in a project integrating mass drug administration (MDA), water, sanitation and hygiene (WaSH), and behavioral change interventions. …
View article: Individual longitudinal compliance to neglected tropical disease mass drug administration programmes, a systematic review
Individual longitudinal compliance to neglected tropical disease mass drug administration programmes, a systematic review Open
Repeated distribution of preventative chemotherapy (PC) by mass drug administration forms the mainstay of transmission control for five of the 20 recognised neglected tropical diseases (NTDs); soil-transmitted helminths, schistosomiasis, l…
View article: Iron homeostasis in full-term, normal birthweight Gambian neonates over the first week of life
Iron homeostasis in full-term, normal birthweight Gambian neonates over the first week of life Open
Human neonates elicit a profound hypoferremia which may protect against bacterial sepsis. We examined the transience of this hypoferremia by measuring iron and its chaperone proteins, inflammatory and haematological parameters over the fir…
View article: Predisposition to soil-transmitted helminth reinfection after four rounds of mass drug administration: results from a longitudinal cohort in the Geshiyaro project, a transmission elimination feasibility study in the Wolaita zone of southern Ethiopia
Predisposition to soil-transmitted helminth reinfection after four rounds of mass drug administration: results from a longitudinal cohort in the Geshiyaro project, a transmission elimination feasibility study in the Wolaita zone of southern Ethiopia Open
Background Current WHO strategies for reaching soil-transmitted helminths (STH) elimination as a public health problem excludes treating certain adult populations in endemic areas, creating infection reservoirs that drive ‘bounce back’ of …
View article: Individual longitudinal compliance to neglected tropical disease mass drug administration programmes, a systematic review
Individual longitudinal compliance to neglected tropical disease mass drug administration programmes, a systematic review Open
Repeated rounds of mass drug administration are the mainstay of transmission control for five of the 20 recognised neglected tropical diseases (NTDs); soil-transmitted helminths, schistosomiasis, lymphatic filariasis, onchocerciasis and tr…
View article: Longitudinal monitoring of prevalence and intensity of soil-transmitted helminth infections as part of community-wide mass drug administration within the Geshiyaro project in the Bolosso Sore district, Wolaita, Ethiopia
Longitudinal monitoring of prevalence and intensity of soil-transmitted helminth infections as part of community-wide mass drug administration within the Geshiyaro project in the Bolosso Sore district, Wolaita, Ethiopia Open
Mass drug administration (MDA), targeted at school-aged children (SAC) is recommended by the World Health Organization for the control of morbidity induced by soil-transmitted helminth (STH) infection in endemic countries. However, MDA doe…
View article: Iron Homeostasis over the First Week of Life: A Prospective Cohort Study in Hospital-Delivered Gambian Neonates
Iron Homeostasis over the First Week of Life: A Prospective Cohort Study in Hospital-Delivered Gambian Neonates Open
OBJECTIVES: Full-term newborns elicit an immediate postnatal hypoferremia at birth. We examined whether preterm and low birthweight babies are capable of a similar response. The transience of this innate defence in full-term babies was ass…