Sukanta Das
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View article: Intestinal Epithelial Cell-derived Osteopontin Protects Against Metabolic Dysfunction–associated Steatohepatitis by Modulating Bile Acid Composition and the Gut Microbiome
Intestinal Epithelial Cell-derived Osteopontin Protects Against Metabolic Dysfunction–associated Steatohepatitis by Modulating Bile Acid Composition and the Gut Microbiome Open
IEC-derived OPN protects against MASH by modulating BA composition and shaping the gut microbiome.
View article: From spectrum to yield: advances in crop photosynthesis with hyperspectral imaging
From spectrum to yield: advances in crop photosynthesis with hyperspectral imaging Open
Ensuring global food security requires noninvasive techniques for optimizing resource use and monitoring crop health. Hyperspectral imaging (HSI) enables the precise analysis of plant physiology by capturing spectral data across narrow ban…
View article: Reliability and fragility analysis of multi-story buildings on layered soil deposits under near and far-field earthquakes: a soil structure interaction study
Reliability and fragility analysis of multi-story buildings on layered soil deposits under near and far-field earthquakes: a soil structure interaction study Open
This study examines the effects of Soil-Structure Interaction (SSI) on frame buildings of varying heights (G + 1, G + 4, and G + 9) constructed over seven different layered soil deposits, each with soft soil deposit layers positioned at va…
View article: Analyzing the Optical Properties of Carom Water at Different Temperature and Concentration
Analyzing the Optical Properties of Carom Water at Different Temperature and Concentration Open
Carom water, infused with the seeds of Ajwain (Carom seeds), has been traditionally used for its medicinal properties. Its optical characteristics, such as transmittance and absorbance, can provide valuable insights into its composition an…
View article: Post-translational modifications drive the effects of HMGB1 in alcohol-associated liver disease
Post-translational modifications drive the effects of HMGB1 in alcohol-associated liver disease Open
Background: We previously identified that high-mobility group box-1 (HMGB1) is increased and undergoes post-translational modifications (PTMs) in response to alcohol consumption. Here, we hypothesized that specific PTMs, occurring mostly i…
View article: Pheromones in Poll Gland secretions of male dromedary camels (Camelus dromedarius) during the breeding season and their role in bio-stimulating sexual behavior changes in females
Pheromones in Poll Gland secretions of male dromedary camels (Camelus dromedarius) during the breeding season and their role in bio-stimulating sexual behavior changes in females Open
View article: Dengue and Malaria Co-infection in a Young Adult with Atypical Feature
Dengue and Malaria Co-infection in a Young Adult with Atypical Feature Open
As an endemic zone, malaria and dengue coinfection can be expected in Bangladesh, although there have not been enough case reports of such coinfection. We describe a previously healthy 22-year-old male from Dhaka, with a history of travell…
View article: A Protein Complex of Liver Origin Activates a Pro-inflammatory Program That Drives Hepatic and Intestinal Injury in Alcohol-Associated Liver Disease
A Protein Complex of Liver Origin Activates a Pro-inflammatory Program That Drives Hepatic and Intestinal Injury in Alcohol-Associated Liver Disease Open
View article: Overexpression of HMGB1 in hepatocytes accelerates PTEN inactivation-induced liver cancer
Overexpression of HMGB1 in hepatocytes accelerates PTEN inactivation-induced liver cancer Open
Background: Liver cancer is increasing due to the rise in metabolic dysfunction-associated steatohepatitis (MASH). High-mobility group box-1 (HMGB1) is involved in the pathogenesis of chronic liver disease, but its role in MASH-associated …
View article: Insight into ovarian follicular dynamics and hormonal interplay during estrus period in Lakhimi cow of Assam
Insight into ovarian follicular dynamics and hormonal interplay during estrus period in Lakhimi cow of Assam Open
Lakhimi is a very promising indigenous dual cattle breed of Assam, India, with their superior draught power capacity, heat tolerance, disease resistance, and adaptability to harsh agro-climatic conditions. The present study was designed to…
View article: Matrisome gene-based subclassification of patients with liver fibrosis identifies clinical and molecular heterogeneities
Matrisome gene-based subclassification of patients with liver fibrosis identifies clinical and molecular heterogeneities Open
Background & Aims: Excessive deposition and crosslinking of extracellular matrix increases liver density and stiffness, promotes fibrogenesis, and increases resistance to fibrinolysis. An emerging therapeutic opportunity in liver fibrosis …
View article: Macrophage-derived Osteopontin (SPP1) Protects From Nonalcoholic Steatohepatitis
Macrophage-derived Osteopontin (SPP1) Protects From Nonalcoholic Steatohepatitis Open
View article: Ablation of high‐mobility group box‐1 in the liver reduces hepatocellular carcinoma but causes hyperbilirubinemia in Hippo signaling‐deficient mice
Ablation of high‐mobility group box‐1 in the liver reduces hepatocellular carcinoma but causes hyperbilirubinemia in Hippo signaling‐deficient mice Open
Silencing the Hippo kinases mammalian sterile 20‐like 1 and 2 (MST1/2) activates the transcriptional coactivator yes‐associated protein (YAP) in human hepatocellular carcinoma (HCC). Hepatocyte‐derived high‐mobility group box‐1 (HMGB1) reg…
View article: Molecular surveillance for operationally relevant genetic polymorphisms in Plasmodium falciparum in Southern Chad, 2016–2017
Molecular surveillance for operationally relevant genetic polymorphisms in Plasmodium falciparum in Southern Chad, 2016–2017 Open
View article: Role of Hepatocyte‐Derived Osteopontin in Liver Carcinogenesis
Role of Hepatocyte‐Derived Osteopontin in Liver Carcinogenesis Open
Osteopontin (OPN) expression correlates with tumor progression in many cancers, including hepatocellular carcinoma (HCC); however, its role in the onset of HCC remains unclear. We hypothesized that increased hepatocyte‐derived OPN is a dri…
View article: The Integrated “Multiomics” Landscape at Peak Injury and Resolution From Alcohol‐Associated Liver Disease
The Integrated “Multiomics” Landscape at Peak Injury and Resolution From Alcohol‐Associated Liver Disease Open
Alcohol‐associated liver disease (ALD) is a significant clinical problem for which the most effective therapy is alcohol abstinence. The two aims of this study were, first, to identify the liver transcriptome, fecal microbiome, and portal …
View article: The Matrisome Genes From Hepatitis B–Related Hepatocellular Carcinoma Unveiled
The Matrisome Genes From Hepatitis B–Related Hepatocellular Carcinoma Unveiled Open
Chronic hepatitis B virus (HBV) infection changes the composition of the extracellular matrix (ECM) and enables the onset and progression of hepatocellular carcinoma (HCC). The ensemble of ECM proteins and associated factors is a major com…
View article: Cefepime Induced Neurotoxicity: Case Series
Cefepime Induced Neurotoxicity: Case Series Open
Cefepime is a broad-spectrum antimicrobial which is widely used for the treatment of both gram positive and gram negative pathogens, mainly in hospital setup for critically ill patients. Its half-life is around two hours and is primarily e…
View article: Osteopontin Takes Center Stage in Chronic Liver Disease
Osteopontin Takes Center Stage in Chronic Liver Disease Open
Osteopontin (OPN) was first identified in 1986. The prefix osteo‐ means bone; however, OPN is expressed in other tissues, including liver. The suffix ‐pontin means bridge and denotes the role of OPN as a link protein within the extracellul…
View article: Histochemical Study of Hair Follicle of Assam Hill Goat (Capra hircus) During Preruminant, Transitional and Ruminant Age Groups
Histochemical Study of Hair Follicle of Assam Hill Goat (Capra hircus) During Preruminant, Transitional and Ruminant Age Groups Open
View article: Exogenous application of osmoprotectants for improving crop physiological parameters and seed yield of rice under high temperature stress
Exogenous application of osmoprotectants for improving crop physiological parameters and seed yield of rice under high temperature stress Open
An investigation was conducted during summer season of 2016-17 and 2017-18 in the Department of Seed Science and Technology, College of Agriculture, OUAT, Bhubaneswar to study the role of osmoprotectants on rice crop physiology and seed yi…
View article: Renal Vein Thrombosis in Idiopathic Thrombocytopenic Purpura
Renal Vein Thrombosis in Idiopathic Thrombocytopenic Purpura Open
Renal Vein Thrombosis (RVT) is thrombotic occlusion of one or both main renal veins, resulting in acute or chronic kidney disease. The clinical presentation of RVT depends on the degree of venous occlusion. Of the various causes of RVT, Id…
View article: Hyperoxidized Albumin Modulates Platelets and Promotes Inflammation Through CD36 Receptor in Severe Alcoholic Hepatitis
Hyperoxidized Albumin Modulates Platelets and Promotes Inflammation Through CD36 Receptor in Severe Alcoholic Hepatitis Open
Hyperoxidized albumin promotes inflammation and modulates several immune cells in severe alcoholic hepatitis (SAH). Platelets mediate inflammation by interacting with immune cells, endothelium, and other cells. The role of hyperoxidized al…
View article: Ablation of Hmgb1 in Intestinal Epithelial Cells Causes Intestinal Lipid Accumulation and Reduces NASH in Mice
Ablation of Hmgb1 in Intestinal Epithelial Cells Causes Intestinal Lipid Accumulation and Reduces NASH in Mice Open
Nonalcoholic steatohepatitis (NASH) is a metabolic disorder in which poor nutrition and the gut‐to‐liver interaction play a major role. We previously established that hepatic high mobility group box‐1 (HMGB1) is involved in chronic liver d…
View article: Hair Tissue Mineral Analysis during Preruminant, Transitional and Ruminant Age Groups in Reference to The Serum T3, T4 and Cortisol in Assam Hill Goat (Capra hircus)
Hair Tissue Mineral Analysis during Preruminant, Transitional and Ruminant Age Groups in Reference to The Serum T3, T4 and Cortisol in Assam Hill Goat (Capra hircus) Open
The present study was conducted in the Assam Hill Goat (Capra hircus) a local variety of Goat of Assam, to investigate the Hair Tissue Mineral patterns (estimated by ICP-OES) during three important metabolic stages viz, preruminant (0-3wee…
View article: Dysregulated Lipid Transport Proteins Correlate With Pathogenesis and Outcome in Severe Alcoholic Hepatitis
Dysregulated Lipid Transport Proteins Correlate With Pathogenesis and Outcome in Severe Alcoholic Hepatitis Open
Severe alcoholic hepatitis (SAH) has high mortality. Dysregulated lipid transport and metabolism in liver/macrophages contributes to disease pathophysiology. Paraoxonase/arylesterase 1 (PON1), a liver‐specific enzyme, inhibits oxidation of…
View article: Biochemical characterization of hair of Assam Hill Goat (Capra hircus) in reference to hair protein and lipid
Biochemical characterization of hair of Assam Hill Goat (Capra hircus) in reference to hair protein and lipid Open
View article: Haemodialysis Permcath-associated Superior Vena Cava Syndrome
Haemodialysis Permcath-associated Superior Vena Cava Syndrome Open
Superior Vena Cava (SVC) syndrome can arise due to obstruction of blood flow in the SVC. Haemodialysis (HD) catheter is very commonly inserted into the SVC, and can lead to thrombotic complications, thereby resulting in signs and symptoms …
View article: Light and scanning electron microscopy of duodenum of cattle (Bos indicus), Asian elephant (Elephas maximus) and Greater one horn Rhinoceros (Rhinoceros unicornis)
Light and scanning electron microscopy of duodenum of cattle (Bos indicus), Asian elephant (Elephas maximus) and Greater one horn Rhinoceros (Rhinoceros unicornis) Open
The present study was conducted on duodenum of Cattle, Elephant and Greater one Horn Rhinoceros for histology and scanning electron microscopy. The mucosal surface of duodenum of cattle, Elephant and Greater one Horn Rhinoceros contained v…
View article: Histomorphometric study of hair follicle of Assam Hill goat during preruminant, transitional and ruminant age groups
Histomorphometric study of hair follicle of Assam Hill goat during preruminant, transitional and ruminant age groups Open
The present investigation was conducted in 18 numbers of Assam Hill Goat divided into three groups (preruminant (0-3 weeks), Transitional (3-8 weeks) and ruminant age groups (above 8 weeks) with six numbers of animals in each group to inve…