Saori Toyoda
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View article: Schizophrenia-related Xpo7 haploinsufficiency leads to behavioral and nuclear transport pathologies
Schizophrenia-related Xpo7 haploinsufficiency leads to behavioral and nuclear transport pathologies Open
Recent genetic studies by the Schizophrenia Exome Sequencing Meta-Analysis (SCHEMA) consortium have identified that protein-truncating variants of exportin 7 (XPO7) can increase the risk of schizophrenia (odds ratio, 28.1). Here we show th…
View article: SMN2 gene copy number affects the incidence and prognosis of motor neuron diseases in Japan
SMN2 gene copy number affects the incidence and prognosis of motor neuron diseases in Japan Open
Our findings suggest that SMN2 copy number reduction may adversely affect the onset and prognosis of MND, including ALS and LMND, in Japanese.
View article: PQBP3 prevents senescence by suppressing PSME3-mediated proteasomal Lamin B1 degradation
PQBP3 prevents senescence by suppressing PSME3-mediated proteasomal Lamin B1 degradation Open
View article: Supplementary Data from A Cohort Study of Cyclin D1 Expression and Prognosis in 602 Colon Cancer Cases
Supplementary Data from A Cohort Study of Cyclin D1 Expression and Prognosis in 602 Colon Cancer Cases Open
Supplementary Data from A Cohort Study of Cyclin D1 Expression and Prognosis in 602 Colon Cancer Cases
View article: Data from A Cohort Study of Cyclin D1 Expression and Prognosis in 602 Colon Cancer Cases
Data from A Cohort Study of Cyclin D1 Expression and Prognosis in 602 Colon Cancer Cases Open
Purpose: Cyclin D1 and cyclin-dependent kinases (CDK) are commonly activated in colorectal cancer. The activity of cyclin D1 can be blocked by CDK inhibitors, including p27 (CDKN1B) and p21 (CDKN1A, which is induced by…
View article: Data from A Cohort Study of Cyclin D1 Expression and Prognosis in 602 Colon Cancer Cases
Data from A Cohort Study of Cyclin D1 Expression and Prognosis in 602 Colon Cancer Cases Open
Purpose: Cyclin D1 and cyclin-dependent kinases (CDK) are commonly activated in colorectal cancer. The activity of cyclin D1 can be blocked by CDK inhibitors, including p27 (CDKN1B) and p21 (CDKN1A, which is induced by…
View article: Supplementary Data from A Cohort Study of Cyclin D1 Expression and Prognosis in 602 Colon Cancer Cases
Supplementary Data from A Cohort Study of Cyclin D1 Expression and Prognosis in 602 Colon Cancer Cases Open
Supplementary Data from A Cohort Study of Cyclin D1 Expression and Prognosis in 602 Colon Cancer Cases
View article: Analyzing schizophrenia-related phenotypes in mice caused by autoantibodies against NRXN1α in schizophrenia
Analyzing schizophrenia-related phenotypes in mice caused by autoantibodies against NRXN1α in schizophrenia Open
The molecular pathological mechanisms underlying schizophrenia remain unclear; however, genomic analysis has identified genes encoding important risk molecules. One such molecule is neurexin 1α (NRXN1α), a presynaptic cell adhesion molecul…