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View article: Efficacy of motixafortide plus G-CSF versus plerixafor plus G-CSF for stem cell mobilization and collection in multiple myeloma: A single-center comparative analysis and interim Results from a prospective study in poor mobilizers
Efficacy of motixafortide plus G-CSF versus plerixafor plus G-CSF for stem cell mobilization and collection in multiple myeloma: A single-center comparative analysis and interim Results from a prospective study in poor mobilizers Open
Introduction Stem cell collection after 4–8 cycles of induction therapy remains standard for multiple myeloma (MM), supporting autologous stem cell rescue/transplantation (ASCT) following high-dose melphalan. The recent growth of cell ther…
Risk factors for the development of orthostatic hypotension during autologous stem cell transplant in patients with multiple myeloma Open
Orthostatic hypotension (OH) is a well-recognized phenomenon occurring in multiple myeloma (MM) patients undergoing autologous stem cell transplant (ASCT), and is associated with significant morbidity and mortality. A retrospective analysi…
Turning over the Beds – How Optimizing Pre-Discharge Patient Teaching Reduced Discharge Delays in the Inpatient Hospital at Dana-Farber Cancer Institute and Brigham and Women's Hospital Open
IntroductionWith rapidly increasing demand at academic medical centers, inpatient resource allocation is a critical focus. Patients receiving autologous stem cell transplant (ASCT) often face complicated discharges, requiring lengthy day o…
Developing an Easily Applicable Quality Improvement Process to Optimize and Improve Discrete Workflows; Methods for Iterative Change and Successful Scale Open
IntroductionWe sought to develop a quality improvement method for workflow and resource optimization that is easy to implement, engages multidisciplinary staff, and can be taught and applied across improvement initiatives. Very busy staff,…
Making Room in the Parking Lot for More Cars - How Changes to Autologous Collection Targets for Patients with Multiple Myeloma Optimized Resource Utilization in the Apheresis Collection Center and Cell Storage Facility at Dana-Farber Cancer Institute Open
IntroductionWith rapidly increasing demand, resources at cellular therapy centers may be stretched thin. Apheresis and processing lab facilities must meet increased collection, processing, and storage requests, necessitating efficiency. We…
Modified Delphi Panel to Prioritize Patient-Reported Outcomes Following Hematopoietic Cell Transplantation Open
Background: The number of adults receiving allogeneic hematopoietic cell transplantation (HCT) in the United States has greatly increased, and transplant-related outcomes have significantly improved. At the same time, research has shown th…
Tapping into Learning: Using Digital Methods for Delivering HSCT Patient Education Open
Background: Hematopoietic stem cell transplantation (HSCT) is a complex process requiring patients to learn complex and non-intuitive concepts over the course of care. Patients describe stressful conditions that affect their ability to mak…