Explanipedia

Age‐associated differences in FIRES: Characterizing prodromal presentation and long‐term outcomes via the web‐based NORSE/FIRES Family Registry Open

Karnig Kazazian, Nicolas Gaspard, Lawrence J. Hirsch, Marissa Kellogg, Sara E. Hocker , et al. · 2025

Febrile infection–related epilepsy syndrome (FIRES) is a rare clinical presentation of refractory status epilepticus following a febrile infection. This study analyzes data from the NORSE/FIRES Family Registry, an international web‐based r…

Communication trends over time in new-onset refractory status epilepticus (NORSE): Interim analysis from the NORSE/FIRES Family Registry Open

Karnig Kazazian, Nicolas Gaspard, Lawrence J. Hirsch, Marissa Kellogg, Sara E. Hocker , et al. · 2024

Guidelines for Neuroprognostication in Critically Ill Adults with Moderate–Severe Traumatic Brain Injury Open

Susanne Muehlschlegel, Venkatakrishna Rajajee, Katja E. Wartenberg, Sheila Alexander, Katharina M. Busl , et al. · 2024

Guidelines for neuroprognostication in adults with traumatic spinal cord injury Open

Dea Mahanes, Susanne Muehlschlegel, Katja E. Wartenberg, Venkatakrishna Rajajee, Sheila Alexander , et al. · 2023

Guidelines for Neuroprognostication in Critically Ill Adults with Intracerebral Hemorrhage Open

David Y. Hwang, Keri S. Kim, Susanne Muehlschlegel, Katja E. Wartenberg, Venkatakrishna Rajajee , et al. · 2023

Author Correction: Guidelines for Neuroprognostication in Adults with Guillain–Barré Syndrome Open

Katharina M. Busl, Herbert Fried, Susanne Muehlschlegel, Katja E. Wartenberg, Venkatakrishna Rajajee , et al. · 2023

Correction to: Guidelines for Neuroprognostication in Adults with Guillain–Barré Syndrome Open

Katharina M. Busl, Herbert Fried, Susanne Muehlschlegel, Katja E. Wartenberg, Venkatakrishna Rajajee , et al. · 2023

Developing DELPHI expert consensus rules for a digital twin model of acute stroke care in the neuro critical care unit Open

Johnny Dang, Amos Lal, Amy Montgomery, Laure Flurin, John M. Litell , et al. · 2023

Guidelines for Neuroprognostication in Adults with Guillain–Barré Syndrome Open

Katharina M. Busl, Herbert Fried, Susanne Muehlschlegel, Katja E. Wartenberg, Venkatakrishna Rajajee , et al. · 2023

Background Guillain–Barré syndrome (GBS) often carries a favorable prognosis. Of adult patients with GBS, 10–30% require mechanical ventilation during the acute phase of the disease. After the acute phase, the focus shifts to restoration o…

Guidelines for Neuroprognostication in Adults with Guillain–Barré Syndrome Open

Katharina M. Busl, Herbert Fried, Susanne Muehlschlegel, Katja E. Wartenberg, Venkatakrishna Rajajee , et al. · 2023

Background Guillain–Barré syndrome (GBS) often carries a favorable prognosis. Of adult patients with GBS, 10–30% require mechanical ventilation during the acute phase of the disease. After the acute phase, the focus shifts to restoration o…

Guidelines for Neuroprognostication in Comatose Adult Survivors of Cardiac Arrest Open

Venkatakrishna Rajajee, Susanne Muehlschlegel, Katja E. Wartenberg, Sheila Alexander, Katharina M. Busl , et al. · 2023

Management of Refractory Status Epilepticus Open

Wei-Ting Chiu, Vanessa Campozano, Alois Josef Schiefecker, Dannys Rivero Rodríguez, Daniel Ferreira , et al. · 2022

This study provides Class III data that propofol and midazolam are equivalently efficacious for RSE.

Acute seizures and status epilepticus in immune effector cell associated neurotoxicity syndrome (ICANS) Open

Jacqui‐Lyn Saw, M Hasib Sidiqi, Michael W. Ruff, Sara E. Hocker, Hassan B. Alkhateeb , et al. · 2022

Diabetic ketoacidosis, cerebral venous sinus thrombosis and fulminant cerebral oedema in COVID-19 infection complicated by <i>Klebsiella pneumoniae</i> infection Open

Lindsey Wallace, Sara E. Hocker, Hilary M. DuBrock, Philippe R. Bauer · 2022

We present an unusual case of a woman in her 30s who was admitted for diabetic ketoacidosis (DKA) in the setting of newly diagnosed but late COVID-19 infection with associated Klebsiella pneumoniae infection. Her altered mental status, out…

Incidence and Predictive Factors Associated with Beta-Lactam Neurotoxicity in the Critically Ill: A Retrospective Cohort Study Open

Natalie A. Haddad, Diana J. Schreier, Jennifer E. Fugate, Ognjen Gajic, Sara E. Hocker , et al. · 2022

A Disclosure About Death Disclosure: Variability in Circulatory Death Determination Open

Christopher Robinson, Suzanne Hunt, Gary Gronseth, Sara E. Hocker, Eelco F. M. Wijdicks , et al. · 2021

Introduction. Circulatory-respiratory death declaration is a common duty of physicians, but little is known about the amount of education and physician practice patterns in completing this examination. Methods. We conducted an online surve…

Pupillometry for Diagnosing Nonconvulsive Status Epilepticus and Assessing Treatment Response? Open

Sara E. Hocker · 2021

How to Help Your Patients Enroll in the New-Onset Refractory Status Epilepticus (NORSE) and Febrile Infection-Related Epilepsy Syndrome (FIRES) Family Registry, and Other Rare Epilepsy Registries Open

Karnig Kazazian, Marissa Kellogg, Nora Wong, Krista Eschbach, Raquel Farias Moeller , et al. · 2021

SCOPUS: ar.j

WITHDRAWN–How to Help Your Patients Enroll in the New-Onset Refractory Status Epilepticus (NORSE) and Febrile Infection-Related Epilepsy Syndrome (FIRES) Family Registry, and Other Rare Epilepsy Registries Open

Karnig Kazazian, Marissa Kellogg, Nora Wong, Krista Eschbach, Raquel Farias Moeller , et al. · 2021

New-onset refractory status epilepticus (NORSE) is a rare clinical presentation of refractory status epilepticus (RSE) that occurs in people without active epilepsy or preexisting neurologic disorder. Febrile infection-related epilepsy syn…

Proceedings from the Neurotherapeutics Symposium on Neurological Emergencies: Shaping the Future of Neurocritical Care Open

Alexis N. Simpkins, Katharina M. Busl, Edilberto Amorim, Carolina Barnett, Mackenzie C. Cervenka , et al. · 2020

Effective treatment options for patients with life-threatening neurological disorders are limited. To address this unmet need, high-impact translational research is essential for the advancement and development of novel therapeutic approac…

Perampanel for Refractory Status Epilepticus… Another Tool in the Armamentarium Open

Sara E. Hocker · 2019

Communication Challenges: A Spotlight on New-Onset Refractory Status Epilepticus Open

Teneille Gofton, Nora Wong, Lawrence J. Hirsch, Sara E. Hocker · 2019

New onset refractory status epilepticus research Open

Teneille Gofton, Nicolas Gaspard, Sara E. Hocker, Tobias Loddenkemper, Lawrence J. Hirsch · 2019

New-onset refractory status epilepticus (NORSE) is a clinical presentation, not a specific diagnosis, in a patient without active epilepsy or other preexisting relevant neurologic disorder, with new onset of refractory status epilepticus (…

Variability in reported physician practices for brain death determination Open

Sherri A. Braksick, Christopher P. Robinson, Gary Gronseth, Sara E. Hocker, Eelco F. M. Wijdicks , et al. · 2019

There is substantial variability in how physicians approach the adult brain death examination, but our survey also identified lack of training in nearly 1 in 4 academic physicians. A formal training course in the principles and proper tech…

Cortical surface intracranial electrodes identify clinically relevant seizures missed on scalp EEG after traumatic intracranial hemorrhage Open

Chris Marcellino, Samuel Lapalme‐Remis, Alejandro A. Rabinstein, Jamie J. Van Gompel, Gregory A. Worrell , et al. · 2018

Seizures and other electrophysiological disturbances are an under‐recognized cause of coma, focal deficits, and prolonged encephalopathy following subdural hematoma evacuation. In these patients, it is possible that seizures remain unrecog…

Issue Information Open

Nicole Chémaly, Emma Losito, Jean Marc Pinard, Agnès Gautier, Nathalie Villeneuve , et al. · 2018

Etiologies and characteristics of refractory status epilepticus cases in different areas of the world: Results from a global audit Open

Monica Ferlisi, Sara E. Hocker, Eugen Trinka, Simon Shorvon · 2018

Summary To describe the demographics, etiologies, types of status epilepticus ( SE ), and outcomes in people with refractory and super‐refractory SE from around the world, we prospectively collected cases of refractory SE ( RSE ) treated w…

Bilateral independent periodic discharges are associated with electrographic seizures and poor outcome: A case-control study Open

Gamaleldin Osman, Rahul Rahangdale, Jeffrey W. Britton, Emily J. Gilmore, Hiba A. Haider , et al. · 2018

Parenteral phenobarbital in status epilepticus revisited: Mayo Clinic experience Open

Sara E. Hocker, Sarah L. Clark, Jeffrey W. Britton · 2018

Summary Despite phenobarbital ( PB ) being a key component in status epilepticus (SE) treatment algorithms for decades, it has fallen out of favor compared to newer nonsedating medications due to potential for respiratory suppression and p…

Anesthetic drugs for the treatment of status epilepticus Open

Sara E. Hocker · 2018

Summary Worsening pharmacoresistance to antiseizure drugs is common with ongoing excitotoxic neuronal and systemic injury. Early initiation of anesthetic drugs in refractory status epilepticus ( RSE ) may halt these processes while allowin…

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