Sara Hassan Hassan Ahmed

Vernomigeodiins A–D, highly oxygenated stigmastane-type steroids isolated from Vernoniastrum migeodii with anti-herpes simplex virus activity Open

Morteza Yazdani, Anita Barta, Anasztázia Hetényi, Muhammad Bello Saidu, Umar Shehu Gallah , et al. · 2025

Previously undescribed steroids vernomigeodiins A-D (1-4), were isolated from the African medicinal plant Vernoniastrum migeodii along with known sterols 5-10 and the tripeptide aurantiamide acetate (11). The isolated steroids featured a s…

Studies on bioactive 6-gingerol derivatives and thymoquinone-protoflavone hybrid molecules Open

Sara Hassan Hassan Ahmed · 2024

Thymoquinone-protoflavone hybrid molecules as potential antitumor agents Open

Sara Hassan Hassan Ahmed, Bizhar Ahmed Tayeb, Tímea Gonda, Gábor Girst, Kornél Szőri , et al. · 2024

We describe herein the synthesis of eight new ester-coupled hybrid compounds from thymoquinone and protoflavone building blocks, and their bioactivity testing against multiple cancer cell lines. Among the hybrids, compound 14 showed promis…

Thymoquinone-Protoflavone Hybrid Molecules as Potential Antitumor Agents Open

Sara Hassan Hassan Ahmed, Bizhar Ahmed Tayeb, Tímea Gonda, Gábor Girst, Kornél Szőri , et al. · 2023

We describe herein the synthesis of eight new ester-coupled hybrid compounds from thymoquinone and protoflavone building blocks, and their bioactivity testing against multiple cancer cell lines. Among the hybrids, compound 14 showed promis…

Activation of Sarco/Endoplasmic Reticulum Ca2+-ATPase by Natural Polyphenolic Compounds. Mechanism of Protection against Oxidative Stress Open

Vladimír Heger, Benesova Barbora, Magdaléna Májeková, Petronela Rezbáriková, Gábor Girst , et al. · 2023

Many redox diseases, including diabetes, are associated with an imbalance of calcium homeostasis, regulated mainly by a Ca2+-ATPase pump (SERCA). Dysfunction of this enzyme may be prevented by natural polyphenolic compounds, representing a…

Preparation and Evaluation of 6-Gingerol Derivatives as Novel Antioxidants and Antiplatelet Agents Open

Sara Hassan Hassan Ahmed, Tímea Gonda, Orinamhe Godwin Agbadua, Gábor Girst, Róbert Berkecz , et al. · 2023

Ginger (Zingiber officinale) is widely used as a spice and a traditional medicine. Many bioactivities have been reported for its extracts and the isolated compounds, including cardiovascular protective effects. Different pathways were sugg…

Thymoquinone-protoflavone hybrids Open

Sara Hassan Hassan Ahmed, István Zupkó, Bizhar Ahmed Tayeb, Tímea Gonda, Gábor Girst , et al. · 2023

3nd Symposium of Young Researchers on Pharmacognosy Open

Ed Kiss, Judit Hohmann, Anita Barta, Zsuzsanna Csilla Dávid, Hassan Hassan , et al. · 2022

Phytochemical investigation of Carex praecox 6. Girst, GáborStudy on peroxynitrite-induced oxidation of hydrocurcumins 7. Hammadi, RehamIsolation and structure determination of pregnane glycosides and lignans from an African species

6-gingerol derivatives and thymoquinone-protoflavones hybrids Open

Sara Hassan Hassan Ahmed · 2022

2nd Symposium of Young Researchers on Pharmacognosy Open

Ed Kiss, Judit Hohmann, Anita Barta, Zsuzsanna Csilla Dávid, Hassan Hassan , et al. · 2021

Phytochemical investigation of Carex praecox 6. Girst, GáborStudy on peroxynitrite-induced oxidation of hydrocurcumins 7. Hammadi, RehamIsolation and structure determination of pregnane glycosides and lignans from an African species

Isolation and synthesis of 6-gingerol and 6-gingerdione derivatives Open

Sara Hassan Hassan Ahmed · 2021

Medicinal chemistry inspired by ginger: exploring the chemical space around 6-gingerol Open

Sara Hassan Hassan Ahmed, Tímea Gonda, Attila Hunyadi · 2021

Structure and reported bioactivities of semi-synthetic and synthetic 6-gingerol derivatives.

Review on Chemistry, Pharmacology and Toxicity of Paracetamol Open

Maha Hilal, Reda El Sayed, Sara Hassan Hassan Ahmed, Shereen Mahmoud · 2019

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