Sara Hosseinian
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View article: Nephroprotective impact of royal jelly against rhabdomyolysis-induced kidney damage in rats.
Nephroprotective impact of royal jelly against rhabdomyolysis-induced kidney damage in rats. Open
Royal jelly safeguards the kidney from rhabdomyolysis-related damage, primarily through its anti-oxidant, anti-apoptotic, and anti-inflammatory effects.
View article: Effect of acute and chronic stress on memory impairment and hippocampal oxidative stress following global cerebral ischemia in adult male rats
Effect of acute and chronic stress on memory impairment and hippocampal oxidative stress following global cerebral ischemia in adult male rats Open
Background and purpose: Stress, especially immobility stress, is quite common and one of the most important and influential risk factors in neurological disorders. This study aimed to investigate the effect of acute and chronic immobility …
View article: Propolis and its therapeutic effects on renal diseases: A review.
Propolis and its therapeutic effects on renal diseases: A review. Open
Propolis is produced by bees using a mixture of bees wax and saliva. It contains several bioactive compounds that mainly induce anti-oxidant and anti-inflammatory effects. In this review, we aimed to investigate the effects of propolis on …
View article: Effects of Dichloromethane and N-Butanol Fractions of Nigella Sativa on ACHN and GP-293 Cell Line Morphology, Viability, and Apoptosis
Effects of Dichloromethane and N-Butanol Fractions of Nigella Sativa on ACHN and GP-293 Cell Line Morphology, Viability, and Apoptosis Open
Background: Renal cell carcinoma (RCC) is among the top death-causing cancers. Medicinal herbs can also have beneficial effects on RCC treatment. In this project, we aimed to study the antitumor effect of dichloromethane and N-butanol frac…
View article: Silibinin effects on cognitive disorders: Hope or treatment?
Silibinin effects on cognitive disorders: Hope or treatment? Open
These results suggest that silibinin can be considered a therapeutic agent for the symptom reduction of cognitive disorders, and it acts by affecting various mechanisms such as inflammation, programmed cell death, and oxidative stress.
View article: <i>Nigella sativa</i> and its main constituent, thymoquinone protect against glycerol-induced acute kidney injury in rats.
<i>Nigella sativa</i> and its main constituent, thymoquinone protect against glycerol-induced acute kidney injury in rats. Open
NS extract and to some extent TQ protect the kidney from rhabdomyolysis-induced injury.
View article: The effect of HTLV1 infection on inflammatory and oxidative parameters in the liver, kidney, and pancreases of BALB/c mice
The effect of HTLV1 infection on inflammatory and oxidative parameters in the liver, kidney, and pancreases of BALB/c mice Open
Viral infections are linked to the progression of inflammatory reactions and oxidative stress that play pivotal roles in systemic diseases. To confirm this phenomenon, in the present study, TNF‐α level and oxidative stress markers were exa…
View article: Kidney tissue engineering using a well-preserved acellular rat kidney scaffold and mesenchymal stem cells.
Kidney tissue engineering using a well-preserved acellular rat kidney scaffold and mesenchymal stem cells. Open
The aim of this study was to acquire an effective method for preparation of rat decellularized kidney scaffolds capable of supporting proliferation and differentiation of human adipose tissue derived mesenchymal stem cells (AD-MSCs) into k…
View article: The role of <i>Artemisia turanica</i> extract on renal oxidative and biochemical markers in STZ-induced diabetes in rat.
The role of <i>Artemisia turanica</i> extract on renal oxidative and biochemical markers in STZ-induced diabetes in rat. Open
These findings suggested that AT extract has therapeutic effects on renal oxidative damage and lipid profile in diabetes, that possibly may be due to its antioxidant and hypolipidemic effects.
View article: Induction of Apoptosis and Growth-Inhibition by Thymoquinone in ACHN and GP-293 Cell Lines in Comparable with Cis-Platinum
Induction of Apoptosis and Growth-Inhibition by Thymoquinone in ACHN and GP-293 Cell Lines in Comparable with Cis-Platinum Open
Our findings demonstrated that TQ and Cis-platinum had cytotoxic and apoptotic effects on both cell lines, However, GP-293 cell line was more sensitive to TQ. Additionally, Cis-platinum was more effective on ACHN cell line than on GP-293 c…
View article: Liver Dysfunction and Oxidative Stress in Streptozotocin-Induced Diabetic Rats: Protective Role of<i>Artemisia</i>Turanica
Liver Dysfunction and Oxidative Stress in Streptozotocin-Induced Diabetic Rats: Protective Role of<i>Artemisia</i>Turanica Open
These findings suggested that A. turanica extract had a therapeutic effect on liver dysfuncyion and oxidative stress induced by diabetes, that may be probably due to its antioxidant and antiinflammatory effects.
View article: Renoprotective Effect of <i>Plantago major</i> Against Proteinuria and Apoptosis Induced by Adriamycin in Rat
Renoprotective Effect of <i>Plantago major</i> Against Proteinuria and Apoptosis Induced by Adriamycin in Rat Open
Our results showed that the P. major extract effectively protects against ADR- induced nephropathy by reducing kidney apoptosis and improving renal functioning in rats.
View article: Doxorubicin-induced renal inflammation in rats: Protective role of Plantago major
Doxorubicin-induced renal inflammation in rats: Protective role of Plantago major Open
Objective: The aim of the present study was to evaluate the possible protective effect of Plantago major (P. major) extract against doxorubicin (DXR)-induced renal inflammation in rats. Materials and Methods: 80 male albino rats were rando…
View article: Doxorubicin-induced renal inflammation in rats: Protective role of <i>Plantago major</i>.
Doxorubicin-induced renal inflammation in rats: Protective role of <i>Plantago major</i>. Open
Present results suggest that hydroethanolic extract of P. major protected renal tissue against DXR-induced renal inflammation.
View article: Plantago major protects against cisplatin-induced renal dysfunction and tissue damage in rats
Plantago major protects against cisplatin-induced renal dysfunction and tissue damage in rats Open
The aim of the present study was to determine the effect of Plantago major (P. major) on cisplatin-induced kidney injury in the rat. Cisplatin was injected on the 6th day of the experiment. Animals were treated with P. major ext…
View article: Renoprotective effect of Nigella sativa against cisplatin-induced nephrotoxicity and oxidative stress in rat
Renoprotective effect of Nigella sativa against cisplatin-induced nephrotoxicity and oxidative stress in rat Open
Cisplatin is one of the important antineoplastic drugs. Its clinical use has been restricted due to severe kidney toxicity. Nigella sativa (N. sativa) is an herbaceous plant with many pharmacologic effects. In the present study, we evaluat…
View article: Mixed hydroalcoholic extracts of Nigella sativa and Curcuma longa improves adriamycin-induced renal injury in rat
Mixed hydroalcoholic extracts of Nigella sativa and Curcuma longa improves adriamycin-induced renal injury in rat Open
Extracts of both Curcuma longa (CL) and Nigella sativa extract (NS) are reported to have protective effects on renal damage. In this study, we investigated the protective effect of a combination of NS and CL on Adriamycin (ADR)-induced ren…
View article: Adriamycin-induced oxidative stress is prevented by mixed hydro-alcoholic extract of Nigella sativa and Curcuma longa in rat kidney.
Adriamycin-induced oxidative stress is prevented by mixed hydro-alcoholic extract of Nigella sativa and Curcuma longa in rat kidney. Open
hydro-alcoholic extracts of N.sativa and C.longa led to an improvement in ADR-induced oxidative stress and mixed administration of the extracts enhanced the aforementioned therapeutic effect.
View article: The protective effect of Nigella sativa against cisplatin-induced nephrotoxicity in rats.
The protective effect of Nigella sativa against cisplatin-induced nephrotoxicity in rats. Open
The current study suggests that N. sativa extract and vitamin E in a dose- and time-dependent manner improved the serum and urine biochemical parameters and kidney function in cisplatin-induced nephrotoxicity in rats. However, it needs mor…