Sara Mahgoub
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View article: Histological severity and hepatic outcomes in patients with MASLD and discrepant FIB-4 and liver stiffness measurement
Histological severity and hepatic outcomes in patients with MASLD and discrepant FIB-4 and liver stiffness measurement Open
Approximately 30% of patients in tertiary centers exhibit discordant FIB-4 and LSM results, with LSM more likely reflecting true severity. While some patients with discordant results may have advanced fibrosis, the overall incidence of LRE…
View article: Long-term liver-related outcomes and liver stiffness progression of statin usage in steatotic liver disease
Long-term liver-related outcomes and liver stiffness progression of statin usage in steatotic liver disease Open
Background Statins have multiple benefits in patients with metabolic-associated steatotic liver disease (MASLD). Aim To explore the effects of statins on the long-term risk of all-cause mortality, liver-related clinical events (LREs) and l…
View article: Vibration-Controlled Transient Elastography Scores to Predict Liver-Related Events in Steatotic Liver Disease
Vibration-Controlled Transient Elastography Scores to Predict Liver-Related Events in Steatotic Liver Disease Open
Importance Metabolic dysfunction–associated steatotic liver disease (MASLD) is currently the most common chronic liver disease worldwide. It is important to develop noninvasive tests to assess the disease severity and prognosis. Objective …
View article: Glucagon-Like Peptide-1 Receptor Agonists in Patients With Cirrhosis: Answering the Unanswered Questions?
Glucagon-Like Peptide-1 Receptor Agonists in Patients With Cirrhosis: Answering the Unanswered Questions? Open
View article: National study of NAFLD management identifies variation in delivery of care in the UK between 2019 to 2022
National study of NAFLD management identifies variation in delivery of care in the UK between 2019 to 2022 Open
View article: Recent treatment advances and practical management of hepatitis D virus
Recent treatment advances and practical management of hepatitis D virus Open
Hepatitis D virus (HDV), also referred to as hepatitis delta virus, is the smallest virus capable of causing human disease. It is unable to replicate on its own and can only propagate in the presence of hepatitis B virus (HBV). Infection w…
View article: Liver Disease and Cell Therapy: Advances Made and Remaining Challenges
Liver Disease and Cell Therapy: Advances Made and Remaining Challenges Open
The limited availability of organs for liver transplantation, the ultimate curative treatment for end stage liver disease, has resulted in a growing and unmet need for alternative therapies. Mesenchymal stromal cells (MSCs) with their broa…
View article: Outcomes of incoming and outgoing second opinions from a UK liver transplant centre
Outcomes of incoming and outgoing second opinions from a UK liver transplant centre Open
Objective Second transplant centre opinions (STCOs) for patients declined for liver transplantation are infrequent. We aimed to identify STCOs outcomes from a tertiary transplant centre. Design Referrals between 2012 and 2020 to Birmingham…
View article: Every colon shouldn’t have a silver lining: an atypical case of colitis caused by a ‘commensal’ organism
Every colon shouldn’t have a silver lining: an atypical case of colitis caused by a ‘commensal’ organism Open
View article: PTU-80 Improving clinicians’ confidence in gastroenterology and hepatology management: simulation via instant messaging- birmingham advance (SIMBA)
PTU-80 Improving clinicians’ confidence in gastroenterology and hepatology management: simulation via instant messaging- birmingham advance (SIMBA) Open
Introduction SIMBA is an innovative virtual simulation-based learning model where participants solve real-life cases using WhatsApp and Zoom. The primary objective of this study was to evaluate the effectiveness and acceptance of case-base…
View article: P030 Outcomes of incoming and outgoing second opinions from a UK liver transplant centre – a roadmap for pan-UK centre data collection
P030 Outcomes of incoming and outgoing second opinions from a UK liver transplant centre – a roadmap for pan-UK centre data collection Open
Background Second (2nd) transplant centre opinions for patients declined for liver transplantation (LT) are considered a rarely needed, but important component of the assessment process. There remains a lack of published data pertaining to…
View article: P046 Liver re-transplantation in adults; a single UK centre experience (2009–2020)
P046 Liver re-transplantation in adults; a single UK centre experience (2009–2020) Open
Liver transplantation is a life -saving modality for liver failure. Graft failure occurs in 5–22% of all liver transplant recipients.1–6 Liver re-transplantation has been considered controversial, with clinical, economic, and e…
View article: P047 Nutrition in decompensated liver disease: A regional trainee-led audit investigating malnutrition and the impact of nutritional interventions following admission with decompensated chronic liver disease
P047 Nutrition in decompensated liver disease: A regional trainee-led audit investigating malnutrition and the impact of nutritional interventions following admission with decompensated chronic liver disease Open
Introduction Malnutrition results in prolonged inpatient stay, high readmission rates and poor clinical outcome.1–3 Malnutrition in cirrhosis is a poor prognostic factor.4 Assessing nutritional status is problematic a…
View article: A case report of glycogen storage disorder in an adult
A case report of glycogen storage disorder in an adult Open
View article: Sequential Cohort Analysis After Liver Transplantation Shows de Novo Extended Release Tacrolimus Is Safe, Efficacious, and Minimizes Renal Dysfunction
Sequential Cohort Analysis After Liver Transplantation Shows de Novo Extended Release Tacrolimus Is Safe, Efficacious, and Minimizes Renal Dysfunction Open
Background. The use of once-daily extended-release tacrolimus (ERT) is associated with improved long-term graft and patient survival when compared with twice-daily tacrolimus (BDT), but the underlying reasons for differential survival are …
View article: Time to endoscopy for acute upper gastrointestinal bleeding: Results from a prospective multicentre trainee‐led audit
Time to endoscopy for acute upper gastrointestinal bleeding: Results from a prospective multicentre trainee‐led audit Open
Background Endoscopy within 24 h of admission (early endoscopy) is a quality standard in acute upper gastrointestinal bleeding (AUGIB). We aimed to audit time to endoscopy outcomes and identify factors affecting delayed endoscopy (>24 h of…