Sara Murías
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View article: Cervical spine arthritis as initial manifestation in Juvenile Idiopathic Arthritis: a multicenter retrospective study
Cervical spine arthritis as initial manifestation in Juvenile Idiopathic Arthritis: a multicenter retrospective study Open
Objective To describe the clinical characteristics, diagnostic findings, treatment, and outcomes of patients with Juvenile Idiopathic Arthritis (JIA) whose initial manifestation was cervical spine arthritis. Methods This retrospective mult…
View article: Inefficiency of Kocher and Caird’s Criteria in Septic Arthritis of the Hip Due to Kingella kingae: A Multicenter Retrospective Cohort Study
Inefficiency of Kocher and Caird’s Criteria in Septic Arthritis of the Hip Due to Kingella kingae: A Multicenter Retrospective Cohort Study Open
In children under 4, septic arthritis of the hip (SAH) caused by Kingella kingae (SAH-KK) can be misdiagnosed, as it does not meet classic septic joint criteria (fever > 38.5°, pain, limited range of motion, and inability to bear weight). …
View article: Disease flares with baricitinib dose reductions and development of flare criteria in patients with CANDLE/PRAAS
Disease flares with baricitinib dose reductions and development of flare criteria in patients with CANDLE/PRAAS Open
We observed disease flares and rebound inflammation with baricitinib dose reductions and proposed flare criteria that can assist in monitoring disease activity and in designing clinical studies in CANDLE/PRAAS.
View article: Severe Thrombocytopenia as the Main Manifestation of Childhood-Onset Systemic Lupus Erythematosus
Severe Thrombocytopenia as the Main Manifestation of Childhood-Onset Systemic Lupus Erythematosus Open
Thrombocytopenia is a common hematologic abnormality of childhood-onset systemic lupus erythematosus (cSLE). Although in most cases thrombocytopenia is mild, severe thrombocytopenia with bleeding complications might occur, and is further c…
View article: Standardized nailfold capillaroscopy in children with rheumatic diseases: a worldwide study
Standardized nailfold capillaroscopy in children with rheumatic diseases: a worldwide study Open
Objectives To standardly assess and describe nailfold videocapillaroscopy (NVC) assessment in children and adolescents with juvenile rheumatic and musculoskeletal diseases (jRMD) vs healthy controls (HCs). Material and methods In consecuti…
View article: Are infections in children with juvenile idiopathic arthritis more frequent than in healthy children? A prospective multicenter observational study
Are infections in children with juvenile idiopathic arthritis more frequent than in healthy children? A prospective multicenter observational study Open
Background Children with juvenile idiopathic arthritis (JIA) might be at a higher risk of infection. Our objectives are to describe and compare infection rates in patients with JIA vs. healthy patients. Methods A prospective, multicenter o…
View article: Use of the Auto-inflammatory Disease Activity Index to monitor disease activity in patients with colchicine-resistant Familial Mediterranean Fever, Mevalonate Kinase Deficiency, and TRAPS treated with canakinumab
Use of the Auto-inflammatory Disease Activity Index to monitor disease activity in patients with colchicine-resistant Familial Mediterranean Fever, Mevalonate Kinase Deficiency, and TRAPS treated with canakinumab Open
View article: Clinical course and seroprevalence of COVID-19 in children with rheumatic diseases—cross-sectional study from a reference centre in Spain
Clinical course and seroprevalence of COVID-19 in children with rheumatic diseases—cross-sectional study from a reference centre in Spain Open
View article: Oral Versus Intravenous Antibiotics for Pediatric Osteoarticular Infection: When and to Whom?
Oral Versus Intravenous Antibiotics for Pediatric Osteoarticular Infection: When and to Whom? Open
Background Osteoarticular infections are typically treated initially with intravenous antibiotics. The objective of this study was to evaluate whether an exclusive oral treatment in selected children may be appropriate. Methods The Spanish…
View article: Canakinumab improves patient-reported outcomes in children and adults with autoinflammatory recurrent fever syndromes: results from the CLUSTER trial
Canakinumab improves patient-reported outcomes in children and adults with autoinflammatory recurrent fever syndromes: results from the CLUSTER trial Open
Patients with three inherited autoinflammatory syndromes experienced sustained improvements on their HRQoL, work/school, and social life on treatment with canakinumab.
View article: Clinical course and seroprevalence of COVID-19 in children with rheumatic diseases. Cross-sectional study from a reference centre in Spain.
Clinical course and seroprevalence of COVID-19 in children with rheumatic diseases. Cross-sectional study from a reference centre in Spain. Open
Background Patients with rheumatic diseases have been considered at risk of COVID-19. A significant percentage of infections in children are asymptomatic or mild and can go unnoticed. This study aims to describe the seroprevalence of SARS-…
View article: Prevalence of thrombotic complications in children with SARS-CoV-2
Prevalence of thrombotic complications in children with SARS-CoV-2 Open
Knowledge of thrombosis in children with SARS-CoV-2 is scarce. In this multicentre national cohort of children with SARS-CoV-2 involving 49 hospitals, 4 patients out of 537 infected children developed a thrombotic complication (prevalence …
View article: COVID-19 in children with rheumatic diseases (RD) in the spanish national cohort EPICO-AEP
COVID-19 in children with rheumatic diseases (RD) in the spanish national cohort EPICO-AEP Open
Objectives SARS-CoV-2 infection in adults with rheumatic diseases (RD) is a cause for concern. Data in the pediatric population are practically absent. We aimed to describe the prevalence of patients with RD and their complications among c…
View article: Fatal outcome of anti-MDA5 juvenile dermatomyositis in a paediatric COVID-19 patient: a case report
Fatal outcome of anti-MDA5 juvenile dermatomyositis in a paediatric COVID-19 patient: a case report Open
Anti-melanoma differentiation-associated gene 5 juvenile dermatomyositis (anti-MDA5 JDM) is associated with high risk of developing rapidly progressive interstitial lung disease (RP-ILD). Here we report an 11-year-old girl with anti-MDA5 J…
View article: Colchicine treatment in children with periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome: A multicenter study in Spain
Colchicine treatment in children with periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome: A multicenter study in Spain Open
Objective: To evaluate the efficacy of colchicine therapy in pediatric patients with PFAPA syndrome who present with an incomplete response to the standard treatment or with frequent episodes (an interval of less than 14 days between two d…
View article: OP0254 CANAKINUMAB IMPROVES PATIENT-REPORTED OUTCOMES IN PATIENTS WITH RECURRENT FEVER SYNDROMES: RESULTS FROM A PHASE 3 TRIAL (CLUSTER)
OP0254 CANAKINUMAB IMPROVES PATIENT-REPORTED OUTCOMES IN PATIENTS WITH RECURRENT FEVER SYNDROMES: RESULTS FROM A PHASE 3 TRIAL (CLUSTER) Open
View article: Biallelic loss-of-function LACC1/FAMIN Mutations Presenting as Rheumatoid Factor-Negative Polyarticular Juvenile Idiopathic Arthritis
Biallelic loss-of-function LACC1/FAMIN Mutations Presenting as Rheumatoid Factor-Negative Polyarticular Juvenile Idiopathic Arthritis Open
Juvenile idiopathic arthritis (JIA) is a complex rheumatic disease with both autoimmune and autoinflammatory components. Recently, familial cases of systemic-onset JIA have been attributed to mutations in LACC1/FAMIN . We describe three af…
View article: THU0565 Needs assessment of training in paediatric rheumatology among spanish paediatricians. multicenter descriptive study
THU0565 Needs assessment of training in paediatric rheumatology among spanish paediatricians. multicenter descriptive study Open
View article: THU0596 Measurement of serum calprotectin mrp8/14 in paediatric patients diagnosed with juvenile idiopathic arthritis and autoinflammatory diseases
THU0596 Measurement of serum calprotectin mrp8/14 in paediatric patients diagnosed with juvenile idiopathic arthritis and autoinflammatory diseases Open
View article: JAK1/2 inhibition with baricitinib in the treatment of autoinflammatory interferonopathies
JAK1/2 inhibition with baricitinib in the treatment of autoinflammatory interferonopathies Open
This research was supported by the Intramural Research Program of the NIH, NIAID, and NIAMS. Baricitinib was provided by Eli Lilly and Company, which is the sponsor of the expanded access program for this drug.
View article: Oral treatment of osteoarticular infections caused by Kingella kingae in children
Oral treatment of osteoarticular infections caused by Kingella kingae in children Open
Cite this article as: Alcobendas R, Murias S, Remesal A, Calvo C. Oral treatment of osteoarticular infections caused by Kingella kingae in children. Eur J Rheumatol 2018; 5: 147-8.
View article: A family carrying a homozygous LACC1 truncated mutation expands the clinical phenotype of this disease beyond systemic-onset juvenile idiopathic arthritis
A family carrying a homozygous LACC1 truncated mutation expands the clinical phenotype of this disease beyond systemic-onset juvenile idiopathic arthritis Open