Sara R. Jaffee
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View article: BurstDR spinal cord stimulation for chronic inflammatory demyelinating polyneuropathy
BurstDR spinal cord stimulation for chronic inflammatory demyelinating polyneuropathy Open
Background: Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) is a neurological disorder in which the immune system attacks the myelin sheath, leading to progressive muscle weakness and sensory loss. Neuropathic pain is a common and…
View article: Identifying Neural Biomarkers of Risk-Taking from Intracranial EEG Recordings
Identifying Neural Biomarkers of Risk-Taking from Intracranial EEG Recordings Open
Risk-taking behavior is associated with neuropsychiatric disorders such as addiction. In this study, we present a data-driven approach to identify neural biomarkers of risk- taking from intracranial stereo-electroencephalography (sEEG) rec…
View article: Neuropsychiatric outcomes in responsive neurostimulation: A single-center experience
Neuropsychiatric outcomes in responsive neurostimulation: A single-center experience Open
Background: Responsive neurostimulation (RNS) is an emerging technology for treating drug-resistant epilepsy (DRE). While seizure outcomes are well-documented, there is a paucity of literature evaluating the postoperative neurocognitive ef…
View article: Burst-type deep brain stimulation of the subthalamic nucleus in Parkinson’s disease: A case series on tolerability and efficacy
Burst-type deep brain stimulation of the subthalamic nucleus in Parkinson’s disease: A case series on tolerability and efficacy Open
Background: Deep brain stimulation (DBS) has become an evidence-based treatment for movement disorders such as Parkinson’s disease (PD). Recent animal studies of DBS suggest that burst-type DBS may specifically activate neuronal subpopulat…
View article: Delayed epidural hematoma after spinal cord stimulator implantation in a patient with von Willebrand disease: Illustration
Delayed epidural hematoma after spinal cord stimulator implantation in a patient with von Willebrand disease: Illustration Open
Background: A patient with von Willebrand disease developed a delayed epidural hematoma originating from the tunneling tract and gluteal generator pocket following the placement of a thoracic spinal cord stimulator (SCS). Case Description:…
View article: Stereo-electroencephalography in the setting of a preexisting deep brain stimulation device: illustrative case
Stereo-electroencephalography in the setting of a preexisting deep brain stimulation device: illustrative case Open
BACKGROUND Deep brain stimulation (DBS) and responsive neurostimulation are increasingly being used to treat drug-resistant epilepsy (DRE). However, patients who experience partial or limited improvement in seizure control could require ad…
View article: Annual Research Review: Cash transfer programs and young people's mental health – a review of studies in the United States
Annual Research Review: Cash transfer programs and young people's mental health – a review of studies in the United States Open
Worldwide, more than one in 10 children or adolescents is diagnosed with a mental disorder. Cash transfer programs, which aim to reduce poverty and improve life outcomes by providing direct cash assistance to families and incentivizing or …
View article: The Promise and Challenges of Integrating Biological and Prevention Sciences: A Community-Engaged Model for the Next Generation of Translational Research
The Promise and Challenges of Integrating Biological and Prevention Sciences: A Community-Engaged Model for the Next Generation of Translational Research Open
Beginning with the successful sequencing of the human genome two decades ago, the possibility of developing personalized health interventions based on one’s biology has captured the imagination of researchers, medical providers, and indivi…
View article: How can (or could) biology inform more effective parenting interventions for childhood aggression?
How can (or could) biology inform more effective parenting interventions for childhood aggression? Open
View article: Editorial: ‘The people they are a changin’ – overview of the 2024 Annual Research Review
Editorial: ‘The people they are a changin’ – overview of the 2024 Annual Research Review Open
Two years ago, the title of my editorial (with thanks to Edmund Sonuga-Barke and Bob Dylan) was 'The times they are a-changin'. This title was meant to highlight the paradigm shifts in the field reflected in the papers included in that yea…
View article: Commentary on the power of predictability: patterns of signals in early life shape neurodevelopment and mental health trajectories
Commentary on the power of predictability: patterns of signals in early life shape neurodevelopment and mental health trajectories Open
As Davis and Glynn observe in the introduction to their review, early life adversity is a significant impediment to healthy child development. Whereas some theoretical accounts emphasize the sheer number of physical and psychosocial risk f…
View article: Evidence for the Association Between Adverse Childhood Family Environment, Child Abuse, and Caregiver Warmth and Cardiovascular Health Across the Lifespan: The Coronary Artery Risk Development in Young Adults (CARDIA) Study
Evidence for the Association Between Adverse Childhood Family Environment, Child Abuse, and Caregiver Warmth and Cardiovascular Health Across the Lifespan: The Coronary Artery Risk Development in Young Adults (CARDIA) Study Open
BACKGROUND: This study aimed to quantify the association between childhood family environment and longitudinal cardiovascular health (CVH) in adult CARDIA (Coronary Artery Risk Development in Young Adults) Study participants. We further in…
View article: The Future of Rental Assistance: Lessons Learned from Implementing and Evaluating a Direct-to-Tenant Cash Assistance Program, PHLHousing.
The Future of Rental Assistance: Lessons Learned from Implementing and Evaluating a Direct-to-Tenant Cash Assistance Program, PHLHousing. Open
This article examines a new rental assistance program in Philadelphia, called PHLHousing+, that disburses unconditional cash payments directly to tenants to eliminate their housing cost burden. The program is designed as a 2.5-year randomi…
View article: Introduction to IDEA Special Issue
Introduction to IDEA Special Issue Open
View article: Resilience to Maltreatment in Early Adulthood Does Not Predict Low Allostatic Load at Midlife.
Resilience to Maltreatment in Early Adulthood Does Not Predict Low Allostatic Load at Midlife. Open
Childhood maltreatment may have enduring effects on physiological functioning that are manifest in elevated allostatic load scores in middle age. Alternatively, resilience to maltreatment-as manifest in positive functioning in socioeconomi…
View article: Editorial: Unsettling ‘settled’ science – the importance of questioning received wisdom about the causes of mental health and neuro‐developmental conditions
Editorial: Unsettling ‘settled’ science – the importance of questioning received wisdom about the causes of mental health and neuro‐developmental conditions Open
The papers included in this year's Annual Research Review represent a heterogenous mix of concerns, zooming out, in some cases, to summarize the state of the science for a particular condition or developmental process and zooming in, in ot…
View article: Childhood environment early life stress, caregiver warmth, and associations with the cortisol diurnal curve in adulthood: The coronary artery risk development in young adults (CARDIA) study
Childhood environment early life stress, caregiver warmth, and associations with the cortisol diurnal curve in adulthood: The coronary artery risk development in young adults (CARDIA) study Open
View article: “Just being there, like a shoulder to lean on”: Resilience and Mental Health among Older Youth in and Aged out of Foster Care during COVID-19
“Just being there, like a shoulder to lean on”: Resilience and Mental Health among Older Youth in and Aged out of Foster Care during COVID-19 Open
View article: ‘Excessive and Unreasonable’: The Relation Between Insight and Clinical Correlates and Treatment Outcomes in Obsessive-Compulsive Disorder Across the Life Course
‘Excessive and Unreasonable’: The Relation Between Insight and Clinical Correlates and Treatment Outcomes in Obsessive-Compulsive Disorder Across the Life Course Open
While some mental disorders are inherently characterized by a disconnect from reality, sufferers of most disorders experience varying degrees of clinical insight—the degree to which someone with a mental illness understands that they are a…
View article: Differential exposure to gun or knife violence over two decades is associated with sibling differences in depression
Differential exposure to gun or knife violence over two decades is associated with sibling differences in depression Open
We tested whether exposure to gun or knife violence over two decades is a cause of depression in young adulthood using data from a nationally representative sample in the United States. The National Longitudinal Study of Adolescent to Adul…
View article: Does caregivers’ use of praise reduce children’s externalizing behavior? A longitudinal observational test in the context of a parenting program.
Does caregivers’ use of praise reduce children’s externalizing behavior? A longitudinal observational test in the context of a parenting program. Open
Caregivers are often encouraged to praise children to reduce externalizing behavior. Although several theoretical perspectives suggest that praise works (e.g., praise reinforces positive behavior), others suggest it may not (e.g., children…
View article: Does Caregivers’ Use of Praise Reduce Children’s Externalizing Behavior? A Longitudinal Observational Test in the Context of a Parenting Program
Does Caregivers’ Use of Praise Reduce Children’s Externalizing Behavior? A Longitudinal Observational Test in the Context of a Parenting Program Open
Caregivers are often encouraged to praise children to reduce externalizing behavior. Although several theoretical perspectives suggest that praise works (e.g., praise reinforces positive behavior), others suggest it may not (e.g., children…
View article: Editorial: ‘In our time’: Has the pandemic changed the way we write and read mental health and neurodevelopmental disorder research reviews?
Editorial: ‘In our time’: Has the pandemic changed the way we write and read mental health and neurodevelopmental disorder research reviews? Open
The past year was marked by upheaval, as countries across the globe shut down in the face of the COVID‐19 pandemic. Although the topics for this year’s Annual Research Review were decided long before most of had heard of the coronavirus, m…
View article: Adverse Childhood Experiences and Frequent Headache by Adolescent Self-Report
Adverse Childhood Experiences and Frequent Headache by Adolescent Self-Report Open
View article: Bullying behaviours and other conduct problems: longitudinal investigation of their independent associations with risk factors and later outcomes
Bullying behaviours and other conduct problems: longitudinal investigation of their independent associations with risk factors and later outcomes Open
View article: Inflammatory consequences of child maltreatment
Inflammatory consequences of child maltreatment Open
View article: Risk factors for disruptive behaviours: protocol for a systematic review and meta-analysis of quasi-experimental evidence
Risk factors for disruptive behaviours: protocol for a systematic review and meta-analysis of quasi-experimental evidence Open
Introduction Disruptive behaviour disorders, including oppositional defiant disorder and conduct disorder, are a common set of diagnoses in childhood and adolescence, with global estimates of 5.7%, 3.6% and 2.1% for any disruptive disorder…
View article: Social Determinants of Cardiovascular Health: Early Life Adversity as a Contributor to Disparities in Cardiovascular Diseases
Social Determinants of Cardiovascular Health: Early Life Adversity as a Contributor to Disparities in Cardiovascular Diseases Open
View article: Editorial: Something new – what's next for child and adolescent psychiatry?
Editorial: Something new – what's next for child and adolescent psychiatry? Open
The start of a new decade is often the moment when people pause to reflect on what they have accomplished in the past 10–20 years and where they would like to be at the start of the next decade. Although not designed as such, the 2020 Annu…
View article: Using discordant twin methods to investigate an environmentally mediated pathway between social support and the reduced likelihood of adolescent psychotic experiences
Using discordant twin methods to investigate an environmentally mediated pathway between social support and the reduced likelihood of adolescent psychotic experiences Open
Background Social support has been shown to be associated with a reduced likelihood of developing psychotic experiences in the general population and even amongst those at high risk due to exposure to multiple forms of victimisation (poly-…