Sara Reithofer
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View article: Rational design of structure‐based vaccines targeting misfolded alpha‐synuclein conformers of Parkinson's disease and related disorders
Rational design of structure‐based vaccines targeting misfolded alpha‐synuclein conformers of Parkinson's disease and related disorders Open
Synucleinopathies, including Parkinson's disease (PD), multiple system atrophy (MSA), and dementia with Lewy bodies (DLB), are neurodegenerative disorders caused by the accumulation of misfolded alpha‐synuclein protein. Developing effectiv…
View article: Vaccination with structurally adapted fungal protein fibrils induces immunity to Parkinson’s disease
Vaccination with structurally adapted fungal protein fibrils induces immunity to Parkinson’s disease Open
The pathological misfolding and aggregation of soluble α-synuclein into toxic oligomers and insoluble amyloid fibrils causes Parkinson’s disease, a progressive age-related neurodegenerative disease for which there is no cure. HET-s is a so…
View article: Rational design of structure-based vaccines targeting misfolded alpha-synuclein conformers of Parkinson’s disease and related disorders
Rational design of structure-based vaccines targeting misfolded alpha-synuclein conformers of Parkinson’s disease and related disorders Open
Background Synucleinopathies, including Parkinson’s disease, multiple system atrophy, and dementia with Lewy bodies, are neurodegenerative disorders caused by the accumulation of misfolded alpha-synuclein protein. Developing effective vacc…
View article: Olfactory stimulation Inhibits Nociceptive Signal Processing at the Input Stage of the Central Trigeminal System
Olfactory stimulation Inhibits Nociceptive Signal Processing at the Input Stage of the Central Trigeminal System Open
The spinal trigeminal nucleus caudalis (SpVc) in the mammalian brainstem serves a pivotal function in pain processing. As the main relay center for nociceptive signals, SpVc conducts pain-related signals from various regions of the head to…
View article: Pavlovian to Instrumental Transfer Responses Do Not Correlate With Addiction-Like Behavior in Rats
Pavlovian to Instrumental Transfer Responses Do Not Correlate With Addiction-Like Behavior in Rats Open
Pavlovian learning plays a prominent role in the etiology of addiction. The influence of Pavlovian conditioning on the expression of an instrumental response can be studied using the Pavlovian-to-instrumental transfer (PIT) paradigm. This …