Sara Yousefi Taemeh
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View article: A male-essential miRNA is key for avian sex chromosome dosage compensation
A male-essential miRNA is key for avian sex chromosome dosage compensation Open
Birds have a sex chromosome system in which females are heterogametic (ZW) and males are homogametic (ZZ)1. The differentiation of avian sex chromosomes from ancestral autosomes entails the loss of most genes from the W chromoso…
View article: Strain-specific variations in the culture of chicken primordial germ cells
Strain-specific variations in the culture of chicken primordial germ cells Open
Efficient long-term cultivation of chicken primordial germ cells (cPGCs) is essential for various avian research and biotechnology applications. Our study aimed to address the challenge of inconsistent culture success by investigating stra…
View article: A male-essential microRNA is key for avian sex chromosome dosage compensation
A male-essential microRNA is key for avian sex chromosome dosage compensation Open
Birds have a sex chromosome system in which females are heterogametic (ZW) and males are homogametic (ZZ). The differentiation of avian sex chromosomes from ancestral autosomes entailed the loss of most genes from the W chromosome during e…
View article: Enhanced cultivation of chicken primordial germ cells
Enhanced cultivation of chicken primordial germ cells Open
The cultivation and expansion of chicken primordial germ cells (cPGCs) are of critical importance for both biotechnological applications and the management of poultry genetic biodiversity. The feeder-free culture system has become the most…
View article: Study of the regulatory elements of the Ovalbumin gene promoter using CRISPR technology in chicken cells
Study of the regulatory elements of the Ovalbumin gene promoter using CRISPR technology in chicken cells Open
View article: Integrating Omics and CRISPR Technology for Identification and Verification of Genomic Safe Harbor Loci in the Chicken Genome
Integrating Omics and CRISPR Technology for Identification and Verification of Genomic Safe Harbor Loci in the Chicken Genome Open
View article: Enhanced Cultivation of Chicken Primordial Germ Cells: A Comparison of Enriched and Defined Media
Enhanced Cultivation of Chicken Primordial Germ Cells: A Comparison of Enriched and Defined Media Open
Background The cultivation and expansion of chicken primordial germ cells (cPGCs) is of critical importance for both biotechnological applications and the management of poultry genetic biodiversity. The feeder-free culture system has becom…
View article: Effect of Glutamine Stability on the Long-term Culture and Line Establishment of Chicken Primordial Germ Cells
Effect of Glutamine Stability on the Long-term Culture and Line Establishment of Chicken Primordial Germ Cells Open
Primordial germ cells (PGCs) are precursors of mature gametes, which transmit genetic information to the next generation. Due to the importance of PGCs in many fields, including developmental biology, genome editing, transgenesis, and cons…
View article: A Multi-Faceted Approach for Prediction of Genome Safe Harbor Loci in the Chicken Genome
A Multi-Faceted Approach for Prediction of Genome Safe Harbor Loci in the Chicken Genome Open
To achieve a reliable and persistent expression, the transgene should be precisely integrated into the genome safe harbor (GSH) loci. Little attention has been paid to find the safe harbor loci of the chicken (Gallus gallus domesticus) gen…
View article: CRISPR/CAS-mediated deletion of the upstream regulatory sequences enhances the estrogen-independent expression of chicken ovalbumin
CRISPR/CAS-mediated deletion of the upstream regulatory sequences enhances the estrogen-independent expression of chicken ovalbumin Open
Avian transgenesis has served as a suitable approach to generate bioreactors for the manufacturing of recombinant proteins. Production in chicken cells comes with significant advantages over other systems including providing the human-like…
View article: Author response for "Meiotic initiation in chicken germ cells is regulated by Cyp26b1 and mesonephros"
Author response for "Meiotic initiation in chicken germ cells is regulated by Cyp26b1 and mesonephros" Open