Sarah Ciurus
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View article: Inhibition of DYRK1B BY C81 impedes inflammatory processes in leukocytes by reducing STAT3 activity
Inhibition of DYRK1B BY C81 impedes inflammatory processes in leukocytes by reducing STAT3 activity Open
Chronic inflammatory diseases are a significant global burden and are associated with dysregulated resolution of inflammation. Therefore, promoting the process of resolution is a promising therapeutic approach. This study presents the pote…
View article: The protein biosynthesis inhibitor vioprolide A evokes anti-angiogenic and pro-survival actions by targeting NOP14 and decreasing VEGF receptor 2- and TAZ-signaling
The protein biosynthesis inhibitor vioprolide A evokes anti-angiogenic and pro-survival actions by targeting NOP14 and decreasing VEGF receptor 2- and TAZ-signaling Open
Angiogenesis contributes to the progression of several diseases including cancer or age-related macular degeneration and is crucially driven by pathologically hyperactive endothelial cells (ECs). Targeting angiogenic processes in ECs thus …
View article: Revealing formate production from carbon monoxide in wild type and mutants of Rnf‐ and Ech‐containing acetogens, <i>Acetobacterium woodii</i> and <i>Thermoanaerobacter kivui</i>
Revealing formate production from carbon monoxide in wild type and mutants of Rnf‐ and Ech‐containing acetogens, <i>Acetobacterium woodii</i> and <i>Thermoanaerobacter kivui</i> Open
Summary Acetogenic bacteria have gained much attraction in recent years as they can produce different biofuels and biochemicals from H 2 plus CO 2 or even CO alone, therefore opening a promising alternative route for the production of biof…
View article: It does not always take two to tango: “Syntrophy” <i>via</i> hydrogen cycling in one bacterial cell
It does not always take two to tango: “Syntrophy” <i>via</i> hydrogen cycling in one bacterial cell Open
Interspecies hydrogen transfer in anoxic ecosystems is essential for the complete microbial breakdown of organic matter to methane. Acetogenic bacteria are key players in anaerobic food webs and have been considered as prime candidates for…