Sarah D. Kocher
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View article: The Fire Ant Social Chromosome Exerts a Major Influence on Genome Regulation
The Fire Ant Social Chromosome Exerts a Major Influence on Genome Regulation Open
Supergenes underlying complex trait polymorphisms ensure that sets of coadapted alleles remain genetically linked. Despite their prevalence in nature, the mechanisms of supergene effects on genome regulation are poorly understood. In the f…
View article: The distribution of fitness effects varies phylogenetically across animals
The distribution of fitness effects varies phylogenetically across animals Open
1 Abstract The distribution of fitness effects (DFE) describes the selection coefficients ( s ) of newly arising mutations and fundamentally influences population genetic processes. However, the extent and mechanisms of DFE variation have …
View article: Bumble bee workers adopt novel behavioral roles and reshape their social networks in the absence of a queen
Bumble bee workers adopt novel behavioral roles and reshape their social networks in the absence of a queen Open
Dominant individuals often structure group organization, but less is known about how social networks differ in their absence or how variation among subordinates contributes to collective outcomes. Bumble bees ( Bombus impatiens ) provide a…
View article: pipemake: A pipeline creation tool using Snakemake for reproducible analysis of biological datasets
pipemake: A pipeline creation tool using Snakemake for reproducible analysis of biological datasets Open
The exponential growth in biological data generation has created an urgent need for efficient, reproducible computational analysis workflows. Here, we present pipemake, a computational platform designed to streamline the development and im…
View article: Neo-Sex Chromosome Evolution in Treehoppers Despite Long-Term X Chromosome Conservation
Neo-Sex Chromosome Evolution in Treehoppers Despite Long-Term X Chromosome Conservation Open
Sex chromosomes follow distinct evolutionary trajectories compared to the rest of the genome. In many cases, sex chromosomes (X and Y or Z and W) significantly differentiate from one another resulting in heteromorphic sex chromosome system…
View article: Repeated Shifts in Sociality Are Associated With Fine-tuning of Highly Conserved and Lineage-Specific Enhancers in a Socially Flexible Bee
Repeated Shifts in Sociality Are Associated With Fine-tuning of Highly Conserved and Lineage-Specific Enhancers in a Socially Flexible Bee Open
Comparative genomic studies of social insects suggest that changes in gene regulation are associated with evolutionary transitions in social behavior, but the activity of predicted regulatory regions has not been tested empirically. We use…
View article: Variation in season length and development time is sufficient to drive the emergence and coexistence of social and solitary behavioural strategies
Variation in season length and development time is sufficient to drive the emergence and coexistence of social and solitary behavioural strategies Open
Season length and its associated variables can influence the expression of social behaviours, including the occurrence of eusociality in insects. Eusociality can vary widely across environmental gradients, both within and between different…
View article: Integrating computer vision and molecular neurobiology to bridge the gap between behavior and the brain
Integrating computer vision and molecular neurobiology to bridge the gap between behavior and the brain Open
View article: Repeated shifts in sociality are associated with fine-tuning of highly conserved and lineage-specific enhancers in a socially flexible bee
Repeated shifts in sociality are associated with fine-tuning of highly conserved and lineage-specific enhancers in a socially flexible bee Open
Comparative genomic studies of social insects suggest that changes in gene regulation are associated with evolutionary transitions in social behavior, but the activity of predicted regulatory regions has not been tested empirically. We use…
View article: The Molecular Substrates of Insect Eusociality
The Molecular Substrates of Insect Eusociality Open
The evolution of eusociality in Hymenoptera—encompassing bees, ants, and wasps—is characterized by multiple gains and losses of social living, making this group a prime model to understand the mechanisms that underlie social behavior and s…
View article: Chromosomal fusion drives sex chromosome evolution in treehoppers despite long-term X chromosome conservation
Chromosomal fusion drives sex chromosome evolution in treehoppers despite long-term X chromosome conservation Open
Sex chromosomes follow distinct evolutionary trajectories compared to the rest of the genome. In many cases, sex chromosomes (X and Y, or Z and W) significantly differentiate from one another resulting in heteromorphic sex chromosome syste…
View article: Variation in season length and development time is sufficient to drive the emergence and coexistence of social and solitary behavioral strategies
Variation in season length and development time is sufficient to drive the emergence and coexistence of social and solitary behavioral strategies Open
Season length and its associated variables can influence the expression of social behaviors, including the occurrence of eusociality in insects. Eusociality can vary widely across environmental gradients, both within and between different …
View article: Developmental transcriptomes predict adult social behaviours in the socially flexible sweat bee, <i>Lasioglossum baleicum</i>
Developmental transcriptomes predict adult social behaviours in the socially flexible sweat bee, <i>Lasioglossum baleicum</i> Open
Natural variation can provide important insights into the genetic and environmental factors that shape social behaviour and its evolution. The sweat bee, Lasioglossum baleicum , is a socially flexible bee capable of producing both solitary…
View article: Hormonal gatekeeping via the blood-brain barrier governs caste-specific behavior in ants
Hormonal gatekeeping via the blood-brain barrier governs caste-specific behavior in ants Open
View article: <scp>NAPS</scp> : Integrating pose estimation and tag‐based tracking
<span>NAPS</span> : Integrating pose estimation and tag‐based tracking Open
Significant advances in computational ethology have allowed the quantification of behaviour in unprecedented detail. Tracking animals in social groups, however, remains challenging as most existing methods can either capture pose or robust…
View article: Developmental transcriptomes predict adult social behaviors in the socially flexible sweat bee,<i>Lasioglossum baleicum</i>
Developmental transcriptomes predict adult social behaviors in the socially flexible sweat bee,<i>Lasioglossum baleicum</i> Open
Natural variation can provide important insights into the genetic and environmental factors that shape social behavior and its evolution. The sweat bee, Lasioglossum baleicum , is a socially flexible bee capable of producing both solitary …
View article: Convergent and complementary selection shaped gains and losses of eusociality in sweat bees
Convergent and complementary selection shaped gains and losses of eusociality in sweat bees Open
View article: NAPS: Integrating pose estimation and tag-based tracking
NAPS: Integrating pose estimation and tag-based tracking Open
Significant advances in computational ethology have allowed the quantification of behavior in unprecedented detail. Tracking animals in social groups, however, remains challenging as most existing methods can either capture pose or robustl…
View article: Isolation disrupts social interactions and destabilizes brain development in bumblebees
Isolation disrupts social interactions and destabilizes brain development in bumblebees Open
View article: Publisher Correction: SLEAP: A deep learning system for multi-animal pose tracking
Publisher Correction: SLEAP: A deep learning system for multi-animal pose tracking Open
View article: SLEAP: A deep learning system for multi-animal pose tracking
SLEAP: A deep learning system for multi-animal pose tracking Open
View article: Isolation disrupts social interactions and destabilizes brain development in bumblebees
Isolation disrupts social interactions and destabilizes brain development in bumblebees Open
Summary Social isolation, particularly in early life, leads to deleterious physiological and behavioral outcomes. Few studies, if any, have been able to capture the behavioral and neurogenomic consequences of early life social isolation to…
View article: Convergent selection on hormone signaling shaped social evolution in bees
Convergent selection on hormone signaling shaped social evolution in bees Open
Sweat bees have repeatedly gained and lost eusociality, a transition from individual to group reproduction. Here, we generate chromosome-length genome assemblies for 17 species and identify genomic signatures of evolutionary trade-offs ass…
View article: SLEAP: Multi-animal pose tracking
SLEAP: Multi-animal pose tracking Open
The desire to understand how the brain generates and patterns behavior has driven rapid methodological innovation to quantify and model natural animal behavior. This has led to important advances in deep learning-based markerless pose esti…
View article: Rate variation in the evolution of non-coding DNA associated with social evolution in bees
Rate variation in the evolution of non-coding DNA associated with social evolution in bees Open
The evolutionary origins of eusociality represent increases in complexity from individual to caste-based, group reproduction. These behavioural transitions have been hypothesized to go hand in hand with an increased ability to regulate whe…
View article: Supplementary material from "Rate variation in the evolution of non-coding DNA associated with social evolution in bees"
Supplementary material from "Rate variation in the evolution of non-coding DNA associated with social evolution in bees" Open
The evolutionary origins of eusociality represent increases in complexity from individual to caste-based, group reproduction. These behavioural transitions have been hypothesized to go hand in hand with an increased ability to regulate whe…
View article: Supplementary tables from Rate variation in the evolution of non-coding DNA associated with social evolution in bees.
Supplementary tables from Rate variation in the evolution of non-coding DNA associated with social evolution in bees. Open
The evolutionary origins of eusociality represent increases in complexity from individual to caste-based, group reproduction. These behavioural transitions have been hypothesized to go hand in hand with an increased ability to regulate whe…
View article: Supplementary tables from Rate variation in the evolution of non-coding DNA associated with social evolution in bees
Supplementary tables from Rate variation in the evolution of non-coding DNA associated with social evolution in bees Open
The evolutionary origins of eusociality represent increases in complexity from individual to caste-based, group reproduction. These behavioural transitions have been hypothesized to go hand in hand with an increased ability to regulate whe…
View article: Developmental Biology among Corbiculate Bees: Bombus impatiens, Including Observations on Its Egg Eclosion
Developmental Biology among Corbiculate Bees: Bombus impatiens, Including Observations on Its Egg Eclosion Open
Rozen, Jerome G., Smith, Corey Shepard, Kocher, Sarah, Wyman, Eli S. (2018): Developmental Biology among Corbiculate Bees: Bombus impatiens, Including Observations on Its Egg Eclosion. American Museum Novitates 2018 (3912): 1-25, DOI: 10.1…
View article: Rate variation in the evolution of non-coding DNA associated with social evolution in bees
Rate variation in the evolution of non-coding DNA associated with social evolution in bees Open
The evolutionary origins of eusociality represent increases in complexity from individual to caste-based, group reproduction. These behavioral transitions have been hypothesized to go hand-in-hand with an increased ability to regulate when…