Sarah Dovgin
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View article: From TgO/GABA-AT, GABA, and T-263 Mutant to Conception of Toxoplasma
From TgO/GABA-AT, GABA, and T-263 Mutant to Conception of Toxoplasma Open
View article: Potent Tetrahydroquinolone Eliminates Apicomplexan Parasites
Potent Tetrahydroquinolone Eliminates Apicomplexan Parasites Open
Apicomplexan infections cause substantial morbidity and mortality, worldwide. New, improved therapies are needed. Herein, we create a next generation anti-apicomplexan lead compound, JAG21, a tetrahydroquinolone, with increased sp3-charact…
View article: Author Correction: New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections
Author Correction: New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections Open
View article: CSGID Solves Structures and Identifies Phenotypes for Five Enzymes in Toxoplasma gondii
CSGID Solves Structures and Identifies Phenotypes for Five Enzymes in Toxoplasma gondii Open
Toxoplasma gondii, an Apicomplexan parasite, causes significant morbidity and mortality, including severe disease in immunocompromised hosts and devastating congenital disease, with no effective treatment for the bradyzoite stage. T…
View article: New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections
New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections Open