Explanipedia

1049 Retrospective Analysis of Patient Reported Outcomes Following Posterior Cruciate Ligament Reconstruction Using a Variety of Graft materials Open

Siân Jones, Stuart Roy · 2025

Aim To determine the efficacy of different graft materials in Posterior Cruciate Ligament (PCL) reconstruction using patient reported outcomes as the basis for analysis. Method Retrospective analysis was made of patient reported measures o…

311. PROGNOSTIC VALUE OF DIFFERENT CIRCUMFERENTIAL MARGIN SITES IN OESOPHAGEAL CANCER: A 10-YEAR COHORT STUDY Open

Ahmed Elshaer, Siân Jones, Samir Mehta, Jeremy D. Hayden, Andrew J. Cockbain , et al. · 2024

Background There’s a growing interest towards the prognostic value of circumferential resection margin (CRM) involvement in oesophageal cancers. However, there is no sufficient data about the association of the site-specific CRM and surviv…

Long-term risk prediction after major lower limb amputation: 1-year results of the PERCEIVE study Open

Brenig Llwyd Gwilym, Philip Pallmann, Cherry-Ann Waldron, Emma Thomas‐Jones, Sarah Milosevic , et al. · 2024

Background Decision-making when considering major lower limb amputation is complex and requires individualized outcome estimation. It is unknown how accurate healthcare professionals or relevant outcome prediction tools are at predicting o…

Embedding a Novel Screening Programme for Sexually Transmitted Infections Within an Ambulatory Emergency Surgical Admissions Unit: An Observational Cohort Study Open

Divolka Ganesh, Ciara Mahon, Siân Jones, Helen Please, Mike Hughes , et al. · 2023

Aims To establish a sexually transmitted infection (STI) screening programme for females presenting to an Emergency Ambulatory Surgical Clinic (ASC), and to analyse incidence and prevalence of STIs as an underlying cause for their abdomina…

1240 Life Expectancy of Octogenarians Following EVAR Open

Emiko Sultana, Shaikh Sanjid Seraj, Siân Jones · 2023

Background The aim of elective Abdominal Aortic Aneurysm (AAA) repair is to prevent premature death from rupture. The Endovascular Aneurysm Repair (EVAR) 2 trial showed that patients with AAA who are not fit for open repair do not benefit …

WTP7.7 A novel sexually transmitted infection (STI) testing and screening programme in an Ambulatory Surgical Clinic (ASC) for female patients presenting with abdominal pain Open

Siân Jones, Divolka Ganesh, Ciara Mahon, Helen Please, Michael D. Hughes , et al. · 2023

Aims Methods Women aged 18-44 years presenting to ASC were offered a voluntary self-collected high vulvovaginal swab for chlamydia and gonorrhoea at triage. Data was collected over one year (Dec 2021-Dec 2022). Testing was offered to 299 p…

Comment on: Watch and wait after neoadjuvant treatment in rectal cancer: comparison of outcomes in patients with and without a complete response at first reassessment in the International Watch & Wait Database (IWWD) Open

Siân Jones, Giodin Perin, Sabapathy P. Balasubramanian · 2023

We write regarding the recent paper by Temmink et al., 1 which was recently discussed at 'CRAMSURG', an online journal club based in the UK (www.cramsurg.org).We would like to congratulate the authors for their efforts in performing this s…

Supplementary Table S3C: Mutations/Sample from Genomic and Immunological Tumor Profiling Identifies Targetable Pathways and Extensive CD8+/PDL1+ Immune Infiltration in Inflammatory Breast Cancer Tumors Open

Christopher A. Hamm, Diarmuid Moran, Kakuturu Rao, Patricia B. Trusk, Karen Pry , et al. · 2023

Mutation summary of individual tissue samples (Mutations with a frequency {greater than or equal to}1%)

Supplemental Figures and Tables legends from Notch1 Mutations Are Drivers of Oral Tumorigenesis Open

Evgeny Izumchenko, Kai Sun, Siân Jones, Mariana Brait, Nishant Agrawal , et al. · 2023

Supplemental Figures and Tables legends

Supplemental Table 5 from Notch1 Mutations Are Drivers of Oral Tumorigenesis Open

Evgeny Izumchenko, Kai Sun, Siân Jones, Mariana Brait, Nishant Agrawal , et al. · 2023

Supplemental Table 5. List of 108 primer pairs designed by Fluidigm Assay Design Group and used in this study for NOTCH1 amplification. Table summarizes the GC-content, length distribution and location of the Access Array amplicons.

Figure S2 from Whole-Genome Sequencing of Salivary Gland Adenoid Cystic Carcinoma Open

Eleni M. Rettig, C. Conover Talbot, Mark Sausen, Siân Jones, Justin A. Bishop , et al. · 2023

Axonal guidance signaling pathway alterations in adenoid cystic carcinoma.

Supplemental Tables 6-11 from Notch1 Mutations Are Drivers of Oral Tumorigenesis Open

Evgeny Izumchenko, Kai Sun, Siân Jones, Mariana Brait, Nishant Agrawal , et al. · 2023

Supplemental Tables 6-11. Supp. Table 6. List of all mutations identified in each of the normal samples. Supp. Table 7. List of the mutations in the unmatched OSCC and leukoplakia samples that were filtered-out as they were present in the …

Supplementary Figures 1 - 6 from Therapeutic Potential of the Poly(ADP-ribose) Polymerase Inhibitor Rucaparib for the Treatment of Sporadic Human Ovarian Cancer Open

Maike Ihnen, Christine zu Eulenburg, Teodora Kolarova, Jing Qi, Kanthinh Manivong , et al. · 2023

PDF file - 603K, Supplemental Figure S1: Gene maps of the BRCA1 (A) and BRCA2 (B) CpG islands examined with bisulfite pyrosequencing. Supplemental Figure S2: Anchorage independent growth inhibition at 1μM rucaparib in soft agar. Of the 39 …

Table S1 from Whole-Genome Sequencing of Salivary Gland Adenoid Cystic Carcinoma Open

Eleni M. Rettig, C. Conover Talbot, Mark Sausen, Siân Jones, Justin A. Bishop , et al. · 2023

Summary of sequence analysis of adenoid cystic carcinoma.

Supplementary Figures 1 - 6 from Therapeutic Potential of the Poly(ADP-ribose) Polymerase Inhibitor Rucaparib for the Treatment of Sporadic Human Ovarian Cancer Open

Maike Ihnen, Christine zu Eulenburg, Teodora Kolarova, Jing Qi, Kanthinh Manivong , et al. · 2023

PDF file - 603K, Supplemental Figure S1: Gene maps of the BRCA1 (A) and BRCA2 (B) CpG islands examined with bisulfite pyrosequencing. Supplemental Figure S2: Anchorage independent growth inhibition at 1μM rucaparib in soft agar. Of the 39 …

Supplemental Figures and Tables legends from Notch1 Mutations Are Drivers of Oral Tumorigenesis Open

Evgeny Izumchenko, Kai Sun, Siân Jones, Mariana Brait, Nishant Agrawal , et al. · 2023

Supplemental Figures and Tables legends

Supplementary Table S3C: Mutations/Sample from Genomic and Immunological Tumor Profiling Identifies Targetable Pathways and Extensive CD8+/PDL1+ Immune Infiltration in Inflammatory Breast Cancer Tumors Open

Christopher A. Hamm, Diarmuid Moran, Kakuturu Rao, Patricia B. Trusk, Karen Pry , et al. · 2023

Mutation summary of individual tissue samples (Mutations with a frequency {greater than or equal to}1%)

Figure S1 from Whole-Genome Sequencing of Salivary Gland Adenoid Cystic Carcinoma Open

Eleni M. Rettig, C. Conover Talbot, Mark Sausen, Siân Jones, Justin A. Bishop , et al. · 2023

Circos plots for chromosomal rearrangements in adenoid cystic carcinoma.

Supplementary Table 1 from Therapeutic Potential of the Poly(ADP-ribose) Polymerase Inhibitor Rucaparib for the Treatment of Sporadic Human Ovarian Cancer Open

Maike Ihnen, Christine zu Eulenburg, Teodora Kolarova, Jing Qi, Kanthinh Manivong , et al. · 2023

PDF file - 66K, Cell lines and culture media.

Supplementary Table S1: NGS-Cancer Panel from Genomic and Immunological Tumor Profiling Identifies Targetable Pathways and Extensive CD8+/PDL1+ Immune Infiltration in Inflammatory Breast Cancer Tumors Open

Christopher A. Hamm, Diarmuid Moran, Kakuturu Rao, Patricia B. Trusk, Karen Pry , et al. · 2023

NGS-Cancer Panel Gene list

Supplemental Figure 1 from Notch1 Mutations Are Drivers of Oral Tumorigenesis Open

Evgeny Izumchenko, Kai Sun, Siân Jones, Mariana Brait, Nishant Agrawal , et al. · 2023

Supplemental Figure 1. List of all NOTCH1 mutations found in Chinese OSCC patients. A. Mutations identified in 22 tumor-normal pairs. B. Mutations found in 28 OSCC samples without matching normal control.

Table S2 from Whole-Genome Sequencing of Salivary Gland Adenoid Cystic Carcinoma Open

Eleni M. Rettig, C. Conover Talbot, Mark Sausen, Siân Jones, Justin A. Bishop , et al. · 2023

Somatic mutations in adenoid cystic carcinoma (N=25 tumors).

Supplementary Table S1: NGS-Cancer Panel from Genomic and Immunological Tumor Profiling Identifies Targetable Pathways and Extensive CD8+/PDL1+ Immune Infiltration in Inflammatory Breast Cancer Tumors Open

Christopher A. Hamm, Diarmuid Moran, Kakuturu Rao, Patricia B. Trusk, Karen Pry , et al. · 2023

NGS-Cancer Panel Gene list

Supplementary Table S3A: Mutations by Gene from Genomic and Immunological Tumor Profiling Identifies Targetable Pathways and Extensive CD8+/PDL1+ Immune Infiltration in Inflammatory Breast Cancer Tumors Open

Christopher A. Hamm, Diarmuid Moran, Kakuturu Rao, Patricia B. Trusk, Karen Pry , et al. · 2023

Gene mutation summary.

Table S4 from Whole-Genome Sequencing of Salivary Gland Adenoid Cystic Carcinoma Open

Eleni M. Rettig, C. Conover Talbot, Mark Sausen, Siân Jones, Justin A. Bishop , et al. · 2023

Somatic chromosomal rearrangements in adenoid cystic carcinoma (N=25).

Table S3 from Whole-Genome Sequencing of Salivary Gland Adenoid Cystic Carcinoma Open

Eleni M. Rettig, C. Conover Talbot, Mark Sausen, Siân Jones, Justin A. Bishop , et al. · 2023

Copy number variations in adenoid cystic carcinoma (N=25).

Figure S1 from Whole-Genome Sequencing of Salivary Gland Adenoid Cystic Carcinoma Open

Eleni M. Rettig, C. Conover Talbot, Mark Sausen, Siân Jones, Justin A. Bishop , et al. · 2023

Circos plots for chromosomal rearrangements in adenoid cystic carcinoma.

Supplemental Figure 3 from Notch1 Mutations Are Drivers of Oral Tumorigenesis Open

Evgeny Izumchenko, Kai Sun, Siân Jones, Mariana Brait, Nishant Agrawal , et al. · 2023

Supplemental Figure 3. A. Association between tumor stage of OSCC patients and NOTCH1 mutation-status. B. Table demonstrates differences in smoking and alcohol consumption rates between the OSCC and leukoplakia patients. C. Table demonstra…

Data from Notch1 Mutations Are Drivers of Oral Tumorigenesis Open

Evgeny Izumchenko, Kai Sun, Siân Jones, Mariana Brait, Nishant Agrawal , et al. · 2023

Disruption of NOTCH1 signaling was recently discovered in head and neck cancer. This study aims to evaluate NOTCH1 alterations in the progression of oral squamous cell carcinoma (OSCC) and compare the occurrence of these mutations in Chine…

Supplemental Tables 1-4 from Notch1 Mutations Are Drivers of Oral Tumorigenesis Open

Evgeny Izumchenko, Kai Sun, Siân Jones, Mariana Brait, Nishant Agrawal , et al. · 2023

Supplemental Tables 1-4. Supp. Table 1. A. List of all OSCC samples used in this study and clinical/pathological data. B. List of 22 matched tumor-normal pairs. Supp. Table 2. List of all normal samples used in this study and clinical/path…

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