Sarah Mann
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View article: Multiplex T-cell Stimulation Assay Utilizing a T-cell Activation Reporter-based Detection System
Multiplex T-cell Stimulation Assay Utilizing a T-cell Activation Reporter-based Detection System Open
Immune tolerance and response are both largely driven by the interactions between the major histocompatibility complex (MHC) expressed by antigen presenting cells (APCs), T-cell receptors (TCRs) on T-cells, and their cognate antigens. Diso…
View article: Multiplex T Cell Stimulation Assay Utilizing a T Cell Activation Reporter-Based Detection System
Multiplex T Cell Stimulation Assay Utilizing a T Cell Activation Reporter-Based Detection System Open
Recent advancements in single cell sequencing technologies allow for identification of numerous immune-receptors expressed by T cells such as tumor-specific and autoimmune T cells. Determining antigen specificity of those cells holds immen…