Sarah H. Saxton
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View article: Topological Tracks Patterned via 3D Printing Vascularize Murine Organ-Scale Constructs
Topological Tracks Patterned via 3D Printing Vascularize Murine Organ-Scale Constructs Open
View article: Highly Parallel Tissue Grafting for Combinatorial In Vivo Screening
Highly Parallel Tissue Grafting for Combinatorial In Vivo Screening Open
Material- and cell-based technologies such as engineered tissues hold great promise as human therapies. Yet, the development of many of these technologies becomes stalled at the stage of pre-clinical animal studies due to the tedious and l…
View article: Temporal Dynamics of Metabolic Acquisition in Grafted Engineered Human Liver Tissue
Temporal Dynamics of Metabolic Acquisition in Grafted Engineered Human Liver Tissue Open
Liver disease affects millions globally, and end‐stage liver failure is only cured by organ transplant. Unfortunately, there is a growing shortage of donor organs as well as inequitable access to transplants across populations. Engineered …
View article: Single-cell atlas of human liver development reveals pathways directing hepatic cell fates
Single-cell atlas of human liver development reveals pathways directing hepatic cell fates Open
View article: 2D and 3D liver models
2D and 3D liver models Open
View article: Temporal dynamics of metabolic acquisition in grafted engineered human liver tissue
Temporal dynamics of metabolic acquisition in grafted engineered human liver tissue Open
Liver disease affects millions globally and end-stage liver failure is only cured by organ transplant. Unfortunately, there is a growing shortage of donor organs and disparities in equitable access to transplants among different population…
View article: Single-cell atlas of human liver development reveals pathways directing hepatic cell fates
Single-cell atlas of human liver development reveals pathways directing hepatic cell fates Open
The liver has been studied extensively due to the broad number of diseases affecting its vital functions. However, therapeutic advances, especially in regenerative medicine, are currently hampered by the lack of knowledge concerning human …
View article: Embryo-scale, single-cell spatial transcriptomics
Embryo-scale, single-cell spatial transcriptomics Open
Localizing gene expression Single-cell RNA sequencing can provide information about cellular relationships based on shared transcriptomes, but most methods lose spatial information. Those methods that do retain spatial information can be l…
View article: Author Correction: Generation of model tissues with dendritic vascular networks via sacrificial laser-sintered carbohydrate templates
Author Correction: Generation of model tissues with dendritic vascular networks via sacrificial laser-sintered carbohydrate templates Open
View article: Robotically handled whole-tissue culture system for the screening of oral drug formulations
Robotically handled whole-tissue culture system for the screening of oral drug formulations Open
View article: Triggerable tough hydrogels for gastric resident dosage forms
Triggerable tough hydrogels for gastric resident dosage forms Open