Sarah J. Goodman
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View article: DNA methylation alterations in acute lymphoblastic leukemia survivors with late neurocognitive deficits
DNA methylation alterations in acute lymphoblastic leukemia survivors with late neurocognitive deficits Open
View article: Psychopharmacology in children with genetic disorders of epigenetic and chromatin regulation
Psychopharmacology in children with genetic disorders of epigenetic and chromatin regulation Open
View article: Peripheral blood DNA methylation and neuroanatomical responses to HDACi treatment that rescues neurological deficits in a Kabuki syndrome mouse model
Peripheral blood DNA methylation and neuroanatomical responses to HDACi treatment that rescues neurological deficits in a Kabuki syndrome mouse model Open
View article: DNA methylation signatures for chromatinopathies: current challenges and future applications
DNA methylation signatures for chromatinopathies: current challenges and future applications Open
View article: X-linked myotubular myopathy is associated with epigenetic alterations and is ameliorated by HDAC inhibition
X-linked myotubular myopathy is associated with epigenetic alterations and is ameliorated by HDAC inhibition Open
View article: Insanity-Plea Bargains: A Constitutionally and Practically Good Idea?
Insanity-Plea Bargains: A Constitutionally and Practically Good Idea? Open
View article: Anatomy of DNA methylation signatures: Emerging insights and applications
Anatomy of DNA methylation signatures: Emerging insights and applications Open
View article: Truncating SRCAP variants outside the Floating-Harbor syndrome locus cause a distinct neurodevelopmental disorder with a specific DNA methylation signature
Truncating SRCAP variants outside the Floating-Harbor syndrome locus cause a distinct neurodevelopmental disorder with a specific DNA methylation signature Open
View article: An Epigenetically Distinct Subset of Children With Autism Spectrum Disorder Resulting From Differences in Blood Cell Composition
An Epigenetically Distinct Subset of Children With Autism Spectrum Disorder Resulting From Differences in Blood Cell Composition Open
Background: Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder that often involves impaired cognition, communication difficulties and restrictive, repetitive behaviors. ASD is extremely heterogeneous both clinically an…
View article: Obsessive-compulsive disorder and attention-deficit/hyperactivity disorder: distinct associations with DNA methylation and genetic variation
Obsessive-compulsive disorder and attention-deficit/hyperactivity disorder: distinct associations with DNA methylation and genetic variation Open
View article: DNA Methylation Signature for EZH2 Functionally Classifies Sequence Variants in Three PRC2 Complex Genes
DNA Methylation Signature for EZH2 Functionally Classifies Sequence Variants in Three PRC2 Complex Genes Open
View article: EHMT1 pathogenic variants and 9q34.3 microdeletions share altered DNA methylation patterns in patients with Kleefstra syndrome
EHMT1 pathogenic variants and 9q34.3 microdeletions share altered DNA methylation patterns in patients with Kleefstra syndrome Open
Aim: Kleefstra syndrome (KS) is a rare neurodevelopmental disorder caused by haploinsufficiency of the euchromatic histone lysine methyltransferase 1 gene, EHMT1, due to either a submicroscopic 9q34.3 deletion or a pathogenic EHMT1 variant…
View article: Additional file 7 of Obsessive-compulsive disorder and attention-deficit/hyperactivity disorder: distinct associations with DNA methylation and genetic variation
Additional file 7 of Obsessive-compulsive disorder and attention-deficit/hyperactivity disorder: distinct associations with DNA methylation and genetic variation Open
Additional file 7: Supplementary Tables S1, Table S2, Table S3.
View article: The Effectiveness of the International Criminal Court: Challenges and Pathways for Prosecuting Human Rights Violations
The Effectiveness of the International Criminal Court: Challenges and Pathways for Prosecuting Human Rights Violations Open
View article: New insights into DNA methylation signatures: SMARCA2 variants in Nicolaides-Baraitser syndrome
New insights into DNA methylation signatures: SMARCA2 variants in Nicolaides-Baraitser syndrome Open
View article: Integration of DNA methylation patterns and genetic variation in human pediatric tissues help inform EWAS design and interpretation
Integration of DNA methylation patterns and genetic variation in human pediatric tissues help inform EWAS design and interpretation Open
View article: Additional file 2: of New insights into DNA methylation signatures: SMARCA2 variants in Nicolaides-Baraitser syndrome
Additional file 2: of New insights into DNA methylation signatures: SMARCA2 variants in Nicolaides-Baraitser syndrome Open
Supplementary Figures and Tables (Tables S1â S4, and S6â S13). (XLSX 183 kb)
View article: MOESM7 of Integration of DNA methylation patterns and genetic variation in human pediatric tissues help inform EWAS design and interpretation
MOESM7 of Integration of DNA methylation patterns and genetic variation in human pediatric tissues help inform EWAS design and interpretation Open
Additional file 7. CpGs classifications across all 419,507 DNAm probes assessed in this study.
View article: Contributions of intrinsic and environmental factors to early life DNA methylation
Contributions of intrinsic and environmental factors to early life DNA methylation Open
Many early experiences and exposures are known to cause health disparities later in life, suggesting that they are somehow ‘biologically embedded’. The mechanisms underlying ‘biological embedding’ are currently not well understood. However…
View article: Children's biobehavioral reactivity to challenge predicts DNA methylation in adolescence and emerging adulthood
Children's biobehavioral reactivity to challenge predicts DNA methylation in adolescence and emerging adulthood Open
A growing body of research has documented associations between adverse childhood environments and DNA methylation, highlighting epigenetic processes as potential mechanisms through which early external contexts influence health across the …
View article: Inhalation of diesel exhaust and allergen alters human bronchial epithelium DNA methylation
Inhalation of diesel exhaust and allergen alters human bronchial epithelium DNA methylation Open
View article: <scp>DNA</scp> methylation and healthy human aging
<span>DNA</span> methylation and healthy human aging Open
Summary The process of aging results in a host of changes at the cellular and molecular levels, which include senescence, telomere shortening, and changes in gene expression. Epigenetic patterns also change over the lifespan, suggesting th…
View article: Prenatal antidepressant exposure associated with<i>CYP2E1</i>DNA methylation change in neonates
Prenatal antidepressant exposure associated with<i>CYP2E1</i>DNA methylation change in neonates Open
Some but not all neonates are affected by prenatal exposure to serotonin reuptake inhibitor antidepressants (SRI) and maternal mood disturbances. Distinguishing the impact of these 2 exposures is challenging and raises critical questions a…
View article: Prenatal antidepressant exposure associated with <i>CYP2E1</i> DNA methylation change in neonates
Prenatal antidepressant exposure associated with <i>CYP2E1</i> DNA methylation change in neonates Open
Some but not all neonates are affected by prenatal exposure to serotonin reuptake inhibitor antidepressants (SRI) and maternal mood disturbances. Distinguishing the impact of these 2 exposures is challenging and raises critical questions a…
View article: Prenatal antidepressant exposure associated with <i>CYP2E1</i> DNA methylation change in neonates
Prenatal antidepressant exposure associated with <i>CYP2E1</i> DNA methylation change in neonates Open
Some but not all neonates are affected by prenatal exposure to serotonin reuptake inhibitor antidepressants (SRI) and maternal mood disturbances. Distinguishing the impact of these 2 exposures is challenging and raises critical questions a…
View article: Prenatal antidepressant exposure associated with <i>CYP2E1</i> DNA methylation change in neonates
Prenatal antidepressant exposure associated with <i>CYP2E1</i> DNA methylation change in neonates Open
Some but not all neonates are affected by prenatal exposure to serotonin reuptake inhibitor antidepressants (SRI) and maternal mood disturbances. Distinguishing the impact of these 2 exposures is challenging and raises critical questions a…
View article: Prenatal antidepressant exposure associated with <i>CYP2E1</i> DNA methylation change in neonates
Prenatal antidepressant exposure associated with <i>CYP2E1</i> DNA methylation change in neonates Open
Some but not all neonates are affected by prenatal exposure to serotonin reuptake inhibitor antidepressants (SRI) and maternal mood disturbances. Distinguishing the impact of these 2 exposures is challenging and raises critical questions a…
View article: Prenatal antidepressant exposure associated with <i>CYP2E1</i> DNA methylation change in neonates
Prenatal antidepressant exposure associated with <i>CYP2E1</i> DNA methylation change in neonates Open
Some but not all neonates are affected by prenatal exposure to serotonin reuptake inhibitor antidepressants (SRI) and maternal mood disturbances. Distinguishing the impact of these two exposures is challenging and raises critical questions…