John Mathai
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View article: Enkephalinergic Neurons in Barrington’s Nucleus Gate Sex-Specific Control of Micturition
Enkephalinergic Neurons in Barrington’s Nucleus Gate Sex-Specific Control of Micturition Open
Lower urinary tract (LUT) control is a vital physiological function governed by a complex interplay between neural circuits and muscle activity. This regulation depends on brainstem circuits, with Barrington’s nucleus (Bar) acting as a cen…
View article: “Enkephalinergic Neurons Gate Sex-Specific Control of Voluntary Micturition”
“Enkephalinergic Neurons Gate Sex-Specific Control of Voluntary Micturition” Open
Summary Lower urinary tract (LUT) control is a vital physiological function, governed by a complex interplay between neural circuits and muscle activity. This regulation depends on brainstem circuits, with Barrington’s nucleus (Bar) acting…
View article: Predictive value of clinico-radiological variables in the management of suspected foreign body aspiration in children: A ten-year retrospective cohort study
Predictive value of clinico-radiological variables in the management of suspected foreign body aspiration in children: A ten-year retrospective cohort study Open
A BSTRACT Background: Definite history is not always present in children with foreign body aspiration (FBA), hence necessitating a high index of suspicion. Objective: To assess the predictive value of clinico-radiological variables among c…
View article: Geospatial methodology for determining the regional prevalence of hospital-reported childhood intussusception in patients from India
Geospatial methodology for determining the regional prevalence of hospital-reported childhood intussusception in patients from India Open
Both developed and developing countries carry a large burden of pediatric intussusception. Sentinel site surveillance-based studies have highlighted the difference in the regional incidence of intussusception. The objectives of this manusc…
View article: A “no-touch” neck “mass” in a child
A “no-touch” neck “mass” in a child Open
Aberrant cervical thymus is a rare cause of pediatric neck masses related to the embryological development. In most of the cases, this condition is asymptomatic and essentially benign in nature. Here, we describe the sonological and magnet…
View article: Idiopathic sudden sensorineural hearing loss – A 12-month review
Idiopathic sudden sensorineural hearing loss – A 12-month review Open
Background: Idiopathic sudden sensorineural hearing loss (ISSNHL) is a condition which is difficult to define and treat. Sensorineural hearing loss being a situation where rehabilitation therapy with hearing aids is the only treatment opti…
View article: Idiopathic sudden sensorineural hearing loss – A 12-month review
Idiopathic sudden sensorineural hearing loss – A 12-month review Open
Background: Idiopathic sudden sensorineural hearing loss (ISSNHL) is a condition which is difficult to define and treat. Sensorineural hearing loss being a situation where rehabilitation therapy with hearing aids is the only treatment opti…
View article: Functional Analysis of Aquaporin-1 Deficient Red Cells: THE COLTON-NULL PHENOTYPE
Functional Analysis of Aquaporin-1 Deficient Red Cells: THE COLTON-NULL PHENOTYPE Open
The aquaporin-1 (AQP1) water transport protein contains a polymorphism corresponding to the Colton red blood cell antigens. To define the fraction of membrane water permeability mediated by AQP1, red cells were obtained from human kindreds…
View article: Functional outcomes in children with reduction glossectomy for vascular malformations - "less is more!"
Functional outcomes in children with reduction glossectomy for vascular malformations - "less is more!" Open
OBJECTIVES: Vascular malformation (VM) of the tongue can cause true macroglossia in children. Reduction glossectomy provides primary relief when sclerotherapy has failed or is not possible. In this study, we evaluated the surgical role in …
View article: Elucidating the anatomy of a rare communicating bronchopulmonary foregut malformation (CBPFM) in a preschool child
Elucidating the anatomy of a rare communicating bronchopulmonary foregut malformation (CBPFM) in a preschool child Open
Communicating bronchopulmonary foregut malformations (CBPFMs) are complex and rare anomalies. Their characteristic feature is an anomalous communication between the respiratory system (trachea, lung or bronchus) on one side and the gastroi…
View article: Risk of intussusception after monovalent rotavirus vaccine (Rotavac) in Indian infants: A self-controlled case series analysis
Risk of intussusception after monovalent rotavirus vaccine (Rotavac) in Indian infants: A self-controlled case series analysis Open
The risk of intussusception during the first 21 days after any dose of rotavirus vaccine (Rotavac) was not higher among the Indian infants than the background risk, based on limited SCCS analysis of 52 children.
View article: Intussusception in children aged under two years in India: Retrospective surveillance at nineteen tertiary care hospitals
Intussusception in children aged under two years in India: Retrospective surveillance at nineteen tertiary care hospitals Open
Intussusception cases have occurred in children across all parts of the country, with low case fatality in the settings studied. The progressive rise cases could indicate an increasing awareness and availability of diagnostic facilities.
View article: A Prospective Cohort Study on the Safety of Infant Pentavalent (DTwP-HBV-Hib) and Oral Polio Vaccines in Two South Indian Districts
A Prospective Cohort Study on the Safety of Infant Pentavalent (DTwP-HBV-Hib) and Oral Polio Vaccines in Two South Indian Districts Open
Background: Safety of pentavalent (DTwP-HBV-Hib) vaccine has been a public concern in India and other countries. This study attempted to document the association of serious adverse events following immunization (AEFI, including hospitaliza…
View article: Comparison of Voiding Cystourethrogram with Cystoscopy in the Prediction of Presence of Posterior Urethral Valve
Comparison of Voiding Cystourethrogram with Cystoscopy in the Prediction of Presence of Posterior Urethral Valve Open
Introduction: Posterior Urethral Valves (PUVs) are a major cause of short and long term morbidity in male children. They cause recurrent urinary tract infections and lead to chronic renal failure in a significant proportion of boys. The di…
View article: Neonatal Cholestasis Syndrome: Aetiological Spectrum and Outcome Analysis- Single Center Study
Neonatal Cholestasis Syndrome: Aetiological Spectrum and Outcome Analysis- Single Center Study Open
Introduction: Neonatal Cholestasis syndrome is a common condition among infants that needs to be evaluated in detail to establish aetiology. Although Idiopathic neonatal hepatitis is common, clear outcome for same has not been established.…
View article: Encouraging results of bowel and bladder management in spina bifida aperta in South India with quality of life scores in a tertiary care institution in South India
Encouraging results of bowel and bladder management in spina bifida aperta in South India with quality of life scores in a tertiary care institution in South India Open
Simple procedures and training for bowel management translate to a significant number of children being able to independently manage bowel care. About 30% of children develop hydronephrosis by 5 years; the decision to teach CIC must be mad…
View article: Outcome and renal function following salvage surgery for bilateral Wilms tumor: a single-institution experience
Outcome and renal function following salvage surgery for bilateral Wilms tumor: a single-institution experience Open
Objective: The aim of this study was to determine the surgical outcomes and renal function following salvage surgery for bilateral Wilms tumor (BWT). Summary background data The challenge for the surgeon treating BWT lies in striking a fin…
View article: Clinicopathological Study of 18 Cases of Inflammatory Myofibroblastic Tumors with Reference to ALK-1 Expression: 5-Year Experience in a Tertiary Care Center
Clinicopathological Study of 18 Cases of Inflammatory Myofibroblastic Tumors with Reference to ALK-1 Expression: 5-Year Experience in a Tertiary Care Center Open
Overall, ALK-1 protein was expressed in 55.6% of inflammatory myofibroblastic tumors. There was no statistically significant correlation between ALK-1 expression, tumor type, recurrence and metastasis. However, ALK-1 immunohistochemistry i…
View article: MP85-06 BRAIN NETWORKS CONTROLLING BLADDER FILLING AND VOIDING
MP85-06 BRAIN NETWORKS CONTROLLING BLADDER FILLING AND VOIDING Open
You have accessJournal of UrologyUrodynamics/Lower Urinary Tract Dysfunction/Female Pelvic Medicine: Neurogenic Voiding Dysfunction I1 Apr 2017MP85-06 BRAIN NETWORKS CONTROLLING BLADDER FILLING AND VOIDING Hanneke Verstegen, John Mathai, M…
View article: Urogenital management in cloaca: An alternative approach
Urogenital management in cloaca: An alternative approach Open
INTRODUCTION: In the management of cloaca, there is concern that dissection of the urogenital sinus in early childhood with the aim of total anatomical correction is hazardous. Avoiding such mobilization and providing mitrofanoff channel, …
View article: Complete Genome Sequence of <i>Serratia marcescens</i> U36365, a Green Pigment–Producing Strain Isolated from a Patient with Urinary Tract Infection
Complete Genome Sequence of <i>Serratia marcescens</i> U36365, a Green Pigment–Producing Strain Isolated from a Patient with Urinary Tract Infection Open
Serratia marcescens is an emerging nosocomial pathogen associated with urinary and respiratory tract infections. In this study, we determined the genome of a green pigment–producing clinical strain, U36365, isolated from a hospital in Sout…
View article: Clinical profile and management options of children with congenital esophageal stenosis: A single center experience
Clinical profile and management options of children with congenital esophageal stenosis: A single center experience Open
Congenital esophageal stenosis is rare and often confused with other causes of esophageal obstruction. Although endoscopic balloon dilatation offers an effective temporary relief, we feel that definitive surgery is curative. Long-term resu…
View article: An assessment of quality of life of operated cases of esophageal atresia in the community
An assessment of quality of life of operated cases of esophageal atresia in the community Open
While survivals of the children born with EA have improved, these children still face nutritional, respiratory, and gastroesophageal problems during their early childhood. In spite of this, the overall QoL of this patient group appears goo…
View article: Enteric duplication in children: Experience from a tertiary center in South India
Enteric duplication in children: Experience from a tertiary center in South India Open
EDs are uncommon and have varied, nonspecific symptoms. Thoracoabdominal duplications are more common in the Indian population. The US is a good screening tool but requires a high index of suspicion where complete excision is not possible;…
View article: Proximal Interruption of the Pulmonary Artery: A Case Series
Proximal Interruption of the Pulmonary Artery: A Case Series Open
We present a few cases of Proximal Interruption of the Pulmonary Artery, an uncommon developmental anomaly associated with congenital heart disease. The cases had varied clinical presentations. Chest radiograph showed a hypoplastic lung wi…