Sarah Lopes Sadafi
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Andexanet alfa vs standard of care for factor Xa inhibitor-induced intracranial hemorrhage—a systematic review and meta-analysis Open
Our meta-analysis found low-certainty evidence supporting improved hemostatic efficacy with andexanet alfa compared with standard of care, with a decrease in mortality and no effect on thrombotic complications. Further randomized data is r…
View article: An Evaluation of Andexanet Alfa v. Standard of Care for Reversal of Doac-Induced Intracranial Hemorrhage - a Systematic Review and Meta-Analysis
An Evaluation of Andexanet Alfa v. Standard of Care for Reversal of Doac-Induced Intracranial Hemorrhage - a Systematic Review and Meta-Analysis Open
Background Direct oral anticoagulants (DOACs) are reversible factor X inhibitors used to treat and prevent thrombotic complications such as venous thromboembolism and stroke in patients with atrial fibrillation. While offering benefits ove…