Sarah Vinnicombe
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View article: FAST MRI: DYAMOND trial protocol (can an abbreviated MRI scan detect breast cancers missed by mammography for screening clients with average mammographic density attending their first screening mammogram?)—a diagnostic yield study within the NHS population-risk breast screening programme
FAST MRI: DYAMOND trial protocol (can an abbreviated MRI scan detect breast cancers missed by mammography for screening clients with average mammographic density attending their first screening mammogram?)—a diagnostic yield study within the NHS population-risk breast screening programme Open
Introduction First post-contrAst SubtracTed (FAST) MRI, an abbreviated breast MRI scan, has high sensitivity for sub-centimetre aggressive breast cancer and short acquisition and interpretation times. These attributes promise effective sup…
View article: Comparison of supplemental breast cancer imaging techniques—interim results from the BRAID randomised controlled trial
Comparison of supplemental breast cancer imaging techniques—interim results from the BRAID randomised controlled trial Open
Cancer Research UK, GE Healthcare, and Bayer Healthcare.
View article: Reproductive factors and mammographic density within the International Consortium of Mammographic Density: A cross-sectional study
Reproductive factors and mammographic density within the International Consortium of Mammographic Density: A cross-sectional study Open
View article: Triple-Negative Pleomorphic Lobular Carcinoma in a BRCA1 Mutation Carrier: A Case of Complete Pathological Response
Triple-Negative Pleomorphic Lobular Carcinoma in a BRCA1 Mutation Carrier: A Case of Complete Pathological Response Open
BACKGROUND Hereditary breast cancer arising in BRCA1-deficient patients is commonly diagnosed as invasive carcinoma of no special type (NST) with medullary features, while invasive lobular carcinoma (ILC) appears to be significantly under-…
View article: Optimising the diagnostic accuracy of First post-contrAst SubtracTed breast MRI (FAST MRI) through interpretation-training: a multicentre e-learning study, mapping the learning curve of NHS Breast Screening Programme (NHSBSP) mammogram readers using an enriched dataset
Optimising the diagnostic accuracy of First post-contrAst SubtracTed breast MRI (FAST MRI) through interpretation-training: a multicentre e-learning study, mapping the learning curve of NHS Breast Screening Programme (NHSBSP) mammogram readers using an enriched dataset Open
View article: The Lancet Breast Cancer Commission
The Lancet Breast Cancer Commission Open
View article: Optimising the diagnostic accuracy of First post-contrAst SubtracTed breast MRI (FAST MRI) through interpretation-training: a multicentre e-learning study, mapping the learning curve of NHS Breast Screening Programme (NHSBSP) mammogram readers using an enriched dataset
Optimising the diagnostic accuracy of First post-contrAst SubtracTed breast MRI (FAST MRI) through interpretation-training: a multicentre e-learning study, mapping the learning curve of NHS Breast Screening Programme (NHSBSP) mammogram readers using an enriched dataset Open
Background: Abbreviated breast MRI (FAST MRI) is being introduced into clinical practice. Specificity optimisation is essential to minimise harm through false positive results for populations with low pre-test probability. This study aimed…
View article: Incidental breast lesions on cross-sectional studies: clinical outcomes, implementation and impact of an alternative referral pathway BREAST 1
Incidental breast lesions on cross-sectional studies: clinical outcomes, implementation and impact of an alternative referral pathway BREAST 1 Open
View article: Predicting the response to neoadjuvant chemotherapy. Can the addition of tomosynthesis improve the accuracy of contrast-enhanced spectral mammography? A comparison with breast MRI
Predicting the response to neoadjuvant chemotherapy. Can the addition of tomosynthesis improve the accuracy of contrast-enhanced spectral mammography? A comparison with breast MRI Open
Objectives Image monitoring is essential to monitor response to neoadjuvant chemotherapy (NACT). Whilst breast MRI is the gold-standard technique, evidence suggests contrast-enhanced spectral mammography (CESM) is comparable. We investigat…
View article: Development and Evaluation of Machine Learning in Whole-Body Magnetic Resonance Imaging for Detecting Metastases in Patients With Lung or Colon Cancer
Development and Evaluation of Machine Learning in Whole-Body Magnetic Resonance Imaging for Detecting Metastases in Patients With Lung or Colon Cancer Open
Objectives Whole-body magnetic resonance imaging (WB-MRI) has been demonstrated to be efficient and cost-effective for cancer staging. The study aim was to develop a machine learning (ML) algorithm to improve radiologists' sensitivity and …
View article: Predicting the response to Neoadjuvant Chemotherapy. Can the addition of tomosynthesis improve the accuracy of CESM? A comparison with breast MRI
Predicting the response to Neoadjuvant Chemotherapy. Can the addition of tomosynthesis improve the accuracy of CESM? A comparison with breast MRI Open
Background Neoadjuvant chemotherapy (NACT) is used to downstage breast cancer prior to surgery. Image monitoring is essential to guide treatment and to assess in vivo chemosensitivity. Breast MRI is considered the gold-standard imaging tec…
View article: A national survey investigating the impact of the COVID-19 pandemic on core and higher breast radiology training in the UK
A national survey investigating the impact of the COVID-19 pandemic on core and higher breast radiology training in the UK Open
View article: Evaluating the effectiveness of abbreviated breast MRI (abMRI) interpretation training for mammogram readers: a multi-centre study assessing diagnostic performance, using an enriched dataset
Evaluating the effectiveness of abbreviated breast MRI (abMRI) interpretation training for mammogram readers: a multi-centre study assessing diagnostic performance, using an enriched dataset Open
View article: The association of age at menarche and adult height with mammographic density in the International Consortium of Mammographic Density
The association of age at menarche and adult height with mammographic density in the International Consortium of Mammographic Density Open
View article: Evaluating the effectiveness of abbreviated breast MRI (abMRI) interpretation-training for mammogram-readers: a multicentre study assessing diagnostic performance, using an enriched dataset
Evaluating the effectiveness of abbreviated breast MRI (abMRI) interpretation-training for mammogram-readers: a multicentre study assessing diagnostic performance, using an enriched dataset Open
Background: Abbreviated breast MRI (abMRI) is being introduced in breast screening trials and clinical practice, particularly for women with dense breasts. Upscaling abMRI provision requires the workforce of mammogram-readers to learn to e…
View article: Contrast-enhanced digital breast tomosythesis and breast MRI to monitor response to neoadjuvant chemotherapy: patient tolerance and preference
Contrast-enhanced digital breast tomosythesis and breast MRI to monitor response to neoadjuvant chemotherapy: patient tolerance and preference Open
Objective: Contrast-enhanced digital breast tomosynthesis (CE-DBT) is a novel imaging technique, combining contrast-enhanced spectral mammography and tomosynthesis. This may offer an alternative imaging technique to breast MRI for monitori…
View article: International Consortium on Mammographic Density: Methodology and population diversity captured across 22 countries
International Consortium on Mammographic Density: Methodology and population diversity captured across 22 countries Open
Mammographic density (MD) is a quantitative trait, measurable in all women, and is among the strongest markers of breast cancer risk. The population-based epidemiology of MD has revealed genetic, lifestyle and societal/environmental determ…
View article: Fair shares: building and benefiting from healthcare AI with mutually beneficial structures and development partnerships
Fair shares: building and benefiting from healthcare AI with mutually beneficial structures and development partnerships Open
View article: Symposium Mammographicum Conference 2021
Symposium Mammographicum Conference 2021 Open
View article: Digital breast tomosynthesis: sensitivity for cancer in younger symptomatic women
Digital breast tomosynthesis: sensitivity for cancer in younger symptomatic women Open
Objective: Full-field digital mammography (FFDM) has limited sensitivity for cancer in younger women with denser breasts. Digital breast tomosynthesis (DBT) can reduce the risk of cancer being obscured by overlying tissue. The primary stud…
View article: Associations between the ultrasound features of invasive breast cancer and breast cancer specific survival
Associations between the ultrasound features of invasive breast cancer and breast cancer specific survival Open
View article: Determining patient abdomen thickness from a single digital radiograph with a computational model: clinical results from a proof of concept study
Determining patient abdomen thickness from a single digital radiograph with a computational model: clinical results from a proof of concept study Open
Objective: A computational model has been created to estimate the abdominal thickness of a patient following an X-ray examination; its intended application is assisting with patient dose audit of paediatric X-ray examinations. This work ev…
View article: Breast MRI and tumour biology predict axillary lymph node response to neoadjuvant chemotherapy for breast cancer
Breast MRI and tumour biology predict axillary lymph node response to neoadjuvant chemotherapy for breast cancer Open
View article: Are baseline ultrasound and mammographic features associated with rates of pathological completes response in patients receiving neoadjuvant chemotherapy for breast cancer?
Are baseline ultrasound and mammographic features associated with rates of pathological completes response in patients receiving neoadjuvant chemotherapy for breast cancer? Open
Background Increasing numbers of breast cancer patients receive neoadjuvant chemotherapy (NACT). We seek to investigate whether baseline mammographic and ultrasound features are associated with complete pathological response (pCR) after NA…
View article: Adjusting for BMI in analyses of volumetric mammographic density and breast cancer risk
Adjusting for BMI in analyses of volumetric mammographic density and breast cancer risk Open
View article: Development of an automated detection algorithm for patient motion blur in digital mammograms
Development of an automated detection algorithm for patient motion blur in digital mammograms Open
The purpose is to develop and validate an automated method for detecting image unsharpness caused by patient motion blur in digital mammograms. The goal is that such a tool would facilitate immediate re-taking of blurred images, which has …
View article: Identification of pathological complete response after neoadjuvant chemotherapy for breast cancer: comparison of greyscale ultrasound, shear wave elastography, and MRI
Identification of pathological complete response after neoadjuvant chemotherapy for breast cancer: comparison of greyscale ultrasound, shear wave elastography, and MRI Open
View article: Symposium Mammographicum 2018 Meeting Abstracts
Symposium Mammographicum 2018 Meeting Abstracts Open
Background: National surveys of doses in mammography have been carried out for the NHS Breast Screening Programme at 3-yearly intervals since 2002 [1,2].These surveys are part of the quality system.As tomosynthesis is now used for assessme…
View article: Pre-operative stromal stiffness measured by shear wave elastography is independently associated with breast cancer-specific survival
Pre-operative stromal stiffness measured by shear wave elastography is independently associated with breast cancer-specific survival Open
View article: Feasibility study to assess the impact of a lifestyle intervention (‘LivingWELL’) in people having an assessment of their family history of colorectal or breast cancer
Feasibility study to assess the impact of a lifestyle intervention (‘LivingWELL’) in people having an assessment of their family history of colorectal or breast cancer Open
Objectives To assess the feasibility of delivering and evaluating a weight management (WM) programme for overweight patients with a family history (FH) of breast cancer (BC) or colorectal cancer (CRC). Study design A two-arm (intervention …