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View article: Ultra-low-dose computed tomography and chest X-ray in follow-up of high-grade soft tissue sarcoma—a prospective comparative study
Ultra-low-dose computed tomography and chest X-ray in follow-up of high-grade soft tissue sarcoma—a prospective comparative study Open
Ultra-low-dose computed tomography (ULD-CT) may combine the high sensitivity of conventional computed tomography (CT) in detecting sarcoma pulmonary metastasis, with a radiation dose in the same magnitude as chest X-ray (CXR). Fifty patien…
View article: Supplementary Figures S1-S3 from Small Molecule BMH-Compounds That Inhibit RNA Polymerase I and Cause Nucleolar Stress
Supplementary Figures S1-S3 from Small Molecule BMH-Compounds That Inhibit RNA Polymerase I and Cause Nucleolar Stress Open
Supplementary Figures S1-S3. Supplementary Figure 1. BMH-9, BMH-22 and BMH-23 cause a reduction in RPA194 half life. Supplementary Figure 2. BMH-9, BMH-22 and BMH-23 do not activate the DNA damage response. Supplementary Figure 3. p53 acti…
View article: Data from Small Molecule BMH-Compounds That Inhibit RNA Polymerase I and Cause Nucleolar Stress
Data from Small Molecule BMH-Compounds That Inhibit RNA Polymerase I and Cause Nucleolar Stress Open
Activation of the p53 pathway has been considered a therapeutic strategy to target cancers. We have previously identified several p53-activating small molecules in a cell-based screen. Two of the compounds activated p53 by causing DNA dama…
View article: Data from Small Molecule BMH-Compounds That Inhibit RNA Polymerase I and Cause Nucleolar Stress
Data from Small Molecule BMH-Compounds That Inhibit RNA Polymerase I and Cause Nucleolar Stress Open
Activation of the p53 pathway has been considered a therapeutic strategy to target cancers. We have previously identified several p53-activating small molecules in a cell-based screen. Two of the compounds activated p53 by causing DNA dama…
View article: Supplementary Figures S1-S3 from Small Molecule BMH-Compounds That Inhibit RNA Polymerase I and Cause Nucleolar Stress
Supplementary Figures S1-S3 from Small Molecule BMH-Compounds That Inhibit RNA Polymerase I and Cause Nucleolar Stress Open
Supplementary Figures S1-S3. Supplementary Figure 1. BMH-9, BMH-22 and BMH-23 cause a reduction in RPA194 half life. Supplementary Figure 2. BMH-9, BMH-22 and BMH-23 do not activate the DNA damage response. Supplementary Figure 3. p53 acti…
View article: Data from DNA Damage Recognition via Activated ATM and p53 Pathway in Nonproliferating Human Prostate Tissue
Data from DNA Damage Recognition via Activated ATM and p53 Pathway in Nonproliferating Human Prostate Tissue Open
DNA damage response (DDR) pathways have been extensively studied in cancer cell lines and mouse models, but little is known about how DNA damage is recognized by different cell types in nonmalignant, slowly replicating human tissues. Here,…
View article: Supplementary Methods, Figures 1-12 from DNA Damage Recognition via Activated ATM and p53 Pathway in Nonproliferating Human Prostate Tissue
Supplementary Methods, Figures 1-12 from DNA Damage Recognition via Activated ATM and p53 Pathway in Nonproliferating Human Prostate Tissue Open
Supplementary Methods, Figures 1-12 from DNA Damage Recognition via Activated ATM and p53 Pathway in Nonproliferating Human Prostate Tissue
View article: Supplementary Methods, Figures 1-12 from DNA Damage Recognition via Activated ATM and p53 Pathway in Nonproliferating Human Prostate Tissue
Supplementary Methods, Figures 1-12 from DNA Damage Recognition via Activated ATM and p53 Pathway in Nonproliferating Human Prostate Tissue Open
Supplementary Methods, Figures 1-12 from DNA Damage Recognition via Activated ATM and p53 Pathway in Nonproliferating Human Prostate Tissue
View article: Data from DNA Damage Recognition via Activated ATM and p53 Pathway in Nonproliferating Human Prostate Tissue
Data from DNA Damage Recognition via Activated ATM and p53 Pathway in Nonproliferating Human Prostate Tissue Open
DNA damage response (DDR) pathways have been extensively studied in cancer cell lines and mouse models, but little is known about how DNA damage is recognized by different cell types in nonmalignant, slowly replicating human tissues. Here,…
View article: Local relapse of soft tissue sarcoma of the extremities or trunk wall operated on with wide margins without radiation therapy
Local relapse of soft tissue sarcoma of the extremities or trunk wall operated on with wide margins without radiation therapy Open
Background The quality of surgical margins is the most important factor affecting local control in soft tissue sarcoma (STS). Despite this, there is no universally accepted consensus on the definition of an adequate surgical margin or on w…
View article: Cancer Risk After Heart Transplantation Highly Elevated in Comparison to General Population
Cancer Risk After Heart Transplantation Highly Elevated in Comparison to General Population Open