Sasan Karimi
YOU?
Author Swipe
View article: Evaluation of Meniere’s disease, allergy, and their association in a group of patients with vertigo using electrocochleography and skin prick test
Evaluation of Meniere’s disease, allergy, and their association in a group of patients with vertigo using electrocochleography and skin prick test Open
Background Meniere’s disease is an idiopathic disorder of the inner ear characterized by episodic vertigo, tinnitus, fluctuating hearing loss, and aural fullness. Allergic disorders have been implicated among the heterogeneous causative fa…
View article: Comprehensive Review of the Utility of Dynamic Contrast-Enhanced MRI for the Diagnosis and Treatment Assessment of Spinal Benign and Malignant Osseous Disease
Comprehensive Review of the Utility of Dynamic Contrast-Enhanced MRI for the Diagnosis and Treatment Assessment of Spinal Benign and Malignant Osseous Disease Open
Conventional MRI is currently the preferred imaging technique for detection and evaluation of malignant spinal lesions. However, this technique is limited in its ability to assess tumor viability. Unlike conventional MRI, dynamic contrast-…
View article: A Comprehensive Theological and Scientific Study of Gestational Surrogacy
A Comprehensive Theological and Scientific Study of Gestational Surrogacy Open
With advancements in science and in response to the desire of childless individuals, surrogacy has emerged as a contemporary method of treating infertility. Intriguingly, due to its novelty, this topic has sparked considerable legal and ju…
View article: T1-Weighted, Dynamic Contrast-Enhanced MR Perfusion Imaging Can Differentiate between Treatment Success and Failure in Spine Metastases Undergoing Radiation Therapy
T1-Weighted, Dynamic Contrast-Enhanced MR Perfusion Imaging Can Differentiate between Treatment Success and Failure in Spine Metastases Undergoing Radiation Therapy Open
The specificity of plasma volume was higher than that of conventional size measurements, suggesting that dynamic contrast-enhanced MR imaging is a powerful tool to discriminate between treatment success and failure.
View article: Delay of Aortic Arterial Input Function Time Improves Detection of Malignant Vertebral Body Lesions on Dynamic Contrast-Enhanced MRI Perfusion
Delay of Aortic Arterial Input Function Time Improves Detection of Malignant Vertebral Body Lesions on Dynamic Contrast-Enhanced MRI Perfusion Open
Dynamic contrast-enhanced MRI (DCE) is an emerging modality in the study of vertebral body malignancies. DCE-MRI analysis relies on a pharmacokinetic model, which assumes that contrast uptake is simultaneous in the feeding of arteries and …
View article: Supplementary Data 1 - 7 from Phase II Study of Bevacizumab, Temozolomide, and Hypofractionated Stereotactic Radiotherapy for Newly Diagnosed Glioblastoma
Supplementary Data 1 - 7 from Phase II Study of Bevacizumab, Temozolomide, and Hypofractionated Stereotactic Radiotherapy for Newly Diagnosed Glioblastoma Open
Supplementary Data 1 ELIGIBILITY CRITERIA. Supplementary Data 2 HYPOFRACTIONATED STEREOTACTIC RADIOTHERAPY PLANNING. Supplementary Data 3 MRI ACQUISITION PARAMETERS AND PROCESSING. Supplementary Data 4 Nanostring-based Tissue Correlates Me…
View article: Data from Molecular and Clinical Effects of Notch Inhibition in Glioma Patients: A Phase 0/I Trial
Data from Molecular and Clinical Effects of Notch Inhibition in Glioma Patients: A Phase 0/I Trial Open
Purpose: High-grade gliomas are associated with a dismal prognosis. Notch inhibition via the gamma-secretase inhibitor RO4929097 has emerged as a potential therapeutic option based on modulation of the cancer-initiating cell (CIS) p…
View article: Data from Molecular and Clinical Effects of Notch Inhibition in Glioma Patients: A Phase 0/I Trial
Data from Molecular and Clinical Effects of Notch Inhibition in Glioma Patients: A Phase 0/I Trial Open
Purpose: High-grade gliomas are associated with a dismal prognosis. Notch inhibition via the gamma-secretase inhibitor RO4929097 has emerged as a potential therapeutic option based on modulation of the cancer-initiating cell (CIS) p…
View article: Supplemental Fig.1-4;Supplemental Tables 1-3; Suipplemental Methods from Molecular and Clinical Effects of Notch Inhibition in Glioma Patients: A Phase 0/I Trial
Supplemental Fig.1-4;Supplemental Tables 1-3; Suipplemental Methods from Molecular and Clinical Effects of Notch Inhibition in Glioma Patients: A Phase 0/I Trial Open
Supp. Fig.1. CONSORT Flow Diagram Supp. Fig.2. MRI Perfusion Parameters Supp. Fig. 3. Immunohistochemistry Supp. Fig. 4. Gene Expression Profile Supp. Table 1. Adverse Events Supp. Table 2. Pharmacokinetic Data Supp. Table 3. Molar Drug Le…
View article: Data from Phase II Study of Bevacizumab, Temozolomide, and Hypofractionated Stereotactic Radiotherapy for Newly Diagnosed Glioblastoma
Data from Phase II Study of Bevacizumab, Temozolomide, and Hypofractionated Stereotactic Radiotherapy for Newly Diagnosed Glioblastoma Open
Purpose: Bevacizumab is associated with decreased vascular permeability that allows for more aggressive radiotherapy schedules. We conducted a phase II trial in newly diagnosed glioblastoma utilizing a novel hypofractionated stereot…
View article: Supplementary Data 1 - 7 from Phase II Study of Bevacizumab, Temozolomide, and Hypofractionated Stereotactic Radiotherapy for Newly Diagnosed Glioblastoma
Supplementary Data 1 - 7 from Phase II Study of Bevacizumab, Temozolomide, and Hypofractionated Stereotactic Radiotherapy for Newly Diagnosed Glioblastoma Open
Supplementary Data 1 ELIGIBILITY CRITERIA. Supplementary Data 2 HYPOFRACTIONATED STEREOTACTIC RADIOTHERAPY PLANNING. Supplementary Data 3 MRI ACQUISITION PARAMETERS AND PROCESSING. Supplementary Data 4 Nanostring-based Tissue Correlates Me…
View article: Data from Phase II Study of Bevacizumab, Temozolomide, and Hypofractionated Stereotactic Radiotherapy for Newly Diagnosed Glioblastoma
Data from Phase II Study of Bevacizumab, Temozolomide, and Hypofractionated Stereotactic Radiotherapy for Newly Diagnosed Glioblastoma Open
Purpose: Bevacizumab is associated with decreased vascular permeability that allows for more aggressive radiotherapy schedules. We conducted a phase II trial in newly diagnosed glioblastoma utilizing a novel hypofractionated stereot…
View article: Supplemental Fig.1-4;Supplemental Tables 1-3; Suipplemental Methods from Molecular and Clinical Effects of Notch Inhibition in Glioma Patients: A Phase 0/I Trial
Supplemental Fig.1-4;Supplemental Tables 1-3; Suipplemental Methods from Molecular and Clinical Effects of Notch Inhibition in Glioma Patients: A Phase 0/I Trial Open
Supp. Fig.1. CONSORT Flow Diagram Supp. Fig.2. MRI Perfusion Parameters Supp. Fig. 3. Immunohistochemistry Supp. Fig. 4. Gene Expression Profile Supp. Table 1. Adverse Events Supp. Table 2. Pharmacokinetic Data Supp. Table 3. Molar Drug Le…
View article: Semisupervised Training of a Brain MRI Tumor Detection Model Using Mined Annotations
Semisupervised Training of a Brain MRI Tumor Detection Model Using Mined Annotations Open
Background Artificial intelligence (AI) applications for cancer imaging conceptually begin with automated tumor detection, which can provide the foundation for downstream AI tasks. However, supervised training requires many image annotatio…
View article: Radiographic and clinical outcomes using intraoperative magnetic resonance imaging for transsphenoidal resection of pituitary adenomas
Radiographic and clinical outcomes using intraoperative magnetic resonance imaging for transsphenoidal resection of pituitary adenomas Open
OBJECTIVE The utility and safety of intraoperative MRI (iMRI) for resection of pituitary adenomas is not clearly established in the context of advances in endoscopic approaches. The goal in this study was to evaluate the safety and efficac…
View article: T1-weighted Dynamic Contrast-enhanced MRI to Differentiate Nonneoplastic and Malignant Vertebral Body Lesions in the Spine
T1-weighted Dynamic Contrast-enhanced MRI to Differentiate Nonneoplastic and Malignant Vertebral Body Lesions in the Spine Open
Background Dynamic contrast agent-enhanced (DCE) perfusion MRI may help differentiate between nonneoplastic and malignant lesions in the spine. Purpose To investigate the correlation between fractional plasma volume (Vp),…
View article: Magnetic resonance spectroscopic imaging in gliomas: clinical diagnosis and radiotherapy planning
Magnetic resonance spectroscopic imaging in gliomas: clinical diagnosis and radiotherapy planning Open
The reprogramming of cellular metabolism is a hallmark of cancer diagnosis and prognosis. Proton magnetic resonance spectroscopic imaging (MRSI) is a non-invasive diagnostic technique for investigating brain metabolism to establish cancer …
View article: Perioperative management of endoscopic transsphenoidal pituitary surgery
Perioperative management of endoscopic transsphenoidal pituitary surgery Open
The contemporary embrace of endoscopic technology in the approach to the anterior skull base has altered the perioperative landscape for patients requiring pituitary surgery. Utility of a multi‐disciplinary unit in management decisions fac…
View article: Reliability of CT myelography versus MRI in the assessment of spinal epidural disease
Reliability of CT myelography versus MRI in the assessment of spinal epidural disease Open
View article: A Potential Role For Apparent Diffusion Coefficient in the Diagnosis of Trilateral Retinoblastoma
A Potential Role For Apparent Diffusion Coefficient in the Diagnosis of Trilateral Retinoblastoma Open
We attempted to investigate the potential role for apparent diffusion coefficient (ADC) to diagnose trilateral retinoblastoma (TRb) by retrospectively reviewing brain magnetic resonance images of retinoblastoma patients. Observations: The …
View article: Genetic variants and cognitive functions in patients with brain tumors
Genetic variants and cognitive functions in patients with brain tumors Open
Background Patients with brain tumors treated with radiotherapy (RT) and chemotherapy (CT) often experience cognitive dysfunction. We reported that single nucleotide polymorphisms (SNPs) in the APOE, COMT, and BDNF genes may influence cogn…
View article: Change in the cross-sectional area of the thecal sac following balloon kyphoplasty for pathological vertebral compression fractures prior to spine stereotactic radiosurgery
Change in the cross-sectional area of the thecal sac following balloon kyphoplasty for pathological vertebral compression fractures prior to spine stereotactic radiosurgery Open
OBJECTIVE Percutaneous vertebral augmentation procedures such as vertebroplasty and kyphoplasty are often performed in cancer patients to relieve mechanical axial-load pain due to pathological collapse deformities. The collapsed vertebrae …
View article: <i>Reply:</i>
<i>Reply:</i> Open
I appreciate the comments in the letter to the Editor and the interest in our publication. The parameters used in our project best fit our dynamic contrast-enhanced (DCE) model with the FDA-approved software. I find the comments interestin…
View article: Differentiating Atypical Hemangiomas and Metastatic Vertebral Lesions: The Role of T1-Weighted Dynamic Contrast-Enhanced MRI
Differentiating Atypical Hemangiomas and Metastatic Vertebral Lesions: The Role of T1-Weighted Dynamic Contrast-Enhanced MRI Open
Our data demonstrate that plasma volume and permeability constant perfusion parameters and qualitative inspection of contrast-enhancement curves can be used to differentiate atypical hemangiomas from vertebral metastatic lesions. This work…
View article: Endoscopic Endonasal Resection of a Lacrimal Duct Oncocytoma
Endoscopic Endonasal Resection of a Lacrimal Duct Oncocytoma Open
Oncocytomas are rare, benign epithelial cell tumors with a propensity for local invasion and malignant transformation. While the incidence of nasolacrimal duct obstruction caused by a lacrimal sac tumor is low, this diagnosis radically alt…
View article: Radiographic patterns of recurrence and pathologic correlation in malignant gliomas treated with bevacizumab
Radiographic patterns of recurrence and pathologic correlation in malignant gliomas treated with bevacizumab Open
tumor (n = 25), mixed tumor/necrosis (n = 5) and all necrosis (n = 2). On diffusion-weighted imaging, 5/32 had restricted diffusion (three mixed and two necrosis). Irrespective of radiographic recurrence pattern, tumor was found in 94% of …
View article: The role of magnetic resonance spectroscopy imaging in patients with diffuse infiltrating pontine gliomas
The role of magnetic resonance spectroscopy imaging in patients with diffuse infiltrating pontine gliomas Open
Poster: ECR 2018 / C-1963 / The role of magnetic resonance spectroscopy imaging in patients with diffuse infiltrating pontine gliomas by: M. E. Laino 1, S. Farouk Sait2, S. Haque3, S. Karimi3, T. Tartaglione4, C. Colosimo5, G. Co…
View article: Intracranial metastasis in fibrolamellar hepatocellular carcinoma
Intracranial metastasis in fibrolamellar hepatocellular carcinoma Open
Fibrolamellar hepatocellular carcinoma (FLHCC) is a rare liver malignancy in adolescents and young adults. Surgery is the mainstay of therapy for primary and metastatic disease. Most patients relapse, with development of both local and dis…
View article: Diffusion Tensor Imaging Shows Corpus Callosum Differences between High‐Grade Gliomas and Metastases
Diffusion Tensor Imaging Shows Corpus Callosum Differences between High‐Grade Gliomas and Metastases Open
BACKGROUND AND PURPOSE The corpus callosum (CC) has an important role in regulating interhemispheric transfer and is thought to be instrumental in contralateral brain reorganization in patients with brain tumors, as suggested by a previous…
View article: Corticosteroid therapy and severity of vasogenic edema in posterior reversible encephalopathy syndrome
Corticosteroid therapy and severity of vasogenic edema in posterior reversible encephalopathy syndrome Open