Sascha W. Weyer
YOU?
Author Swipe
View article: Distinct <i>in vivo</i> roles of secreted <scp>APP</scp> ectodomain variants <scp>APP</scp> sα and <scp>APP</scp> sβ in regulation of spine density, synaptic plasticity, and cognition
Distinct <i>in vivo</i> roles of secreted <span>APP</span> ectodomain variants <span>APP</span> sα and <span>APP</span> sβ in regulation of spine density, synaptic plasticity, and cognition Open
View article: Amyloid Precursor Protein Protects Neuronal Network Function after Hypoxia via Control of Voltage-Gated Calcium Channels
Amyloid Precursor Protein Protects Neuronal Network Function after Hypoxia via Control of Voltage-Gated Calcium Channels Open
Amyloid precursor protein (APP) is involved in the pathophysiology of Alzheimer's disease, but its normal function in the brain remains elusive. Here, we describe a neuroprotective role of the protein in acute hypoxia. Functional recovery …
View article: 59. APPsα Gene Therapy for Alzheimer's Disease
59. APPsα Gene Therapy for Alzheimer's Disease Open
Alzheimer's disease (AD) is characterized by synaptic failure, dendritic and axonal atrophy, neuronal death and progressive loss of cognitive functions asociéted with β-amyloid accumulation and neurofibrillary tangles of phosphorylated Tau…
View article: Impaired theta-gamma coupling in APP-deficient mice
Impaired theta-gamma coupling in APP-deficient mice Open
View article: The APP Intracellular Domain Is Required for Normal Synaptic Morphology, Synaptic Plasticity, and Hippocampus-Dependent Behavior
The APP Intracellular Domain Is Required for Normal Synaptic Morphology, Synaptic Plasticity, and Hippocampus-Dependent Behavior Open
The amyloid precursor protein family (APP/APLPs) has essential roles for neuromuscular synapse development and for the formation and plasticity of synapses within the CNS. Despite this, it has remained unclear whether APP mediates its func…