Satoko Shimada
YOU?
Author Swipe
View article: Correction to: Prognostic impact of ER‑staining patterns and heterogeneity of ER positive HER2 negative breast cancer
Correction to: Prognostic impact of ER‑staining patterns and heterogeneity of ER positive HER2 negative breast cancer Open
View article: Prognostic Impact of ER-Staining Patterns and Heterogeneity of ER positive HER2 negative Breast Cancer
Prognostic Impact of ER-Staining Patterns and Heterogeneity of ER positive HER2 negative Breast Cancer Open
Background Estrogen receptor (ER) expression is critical in breast cancer treatment. While low ER (1%-9%) resembles triple-negative cancer with chemotherapy efficacy, the significance of “intermediate expression” (≥ 10%) and the therapeuti…
View article: Increased sputum peripheral helper T cells are associated with the severity of rheumatoid arthritis but not with the severity of airway disease
Increased sputum peripheral helper T cells are associated with the severity of rheumatoid arthritis but not with the severity of airway disease Open
Objective Peripheral helper T (Tph) cells, together with plasma cells, are the major pathogenic lymphocytes in the synovium in rheumatoid arthritis (RA). However, whether these cells are involved in RA-associated lung and/or airway disease…
View article: Rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone combined with high-dose methotrexate plus intrathecal chemotherapy for newly diagnosed intravascular large B-cell lymphoma (PRIMEUR-IVL): long-term results of a multicentre, single-arm, phase 2 trial
Rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone combined with high-dose methotrexate plus intrathecal chemotherapy for newly diagnosed intravascular large B-cell lymphoma (PRIMEUR-IVL): long-term results of a multicentre, single-arm, phase 2 trial Open
View article: Delayed Diagnosis of Primary Pulmonary Sarcoma Arising from a Pulmonary Cyst in an Adult: A Case Report
Delayed Diagnosis of Primary Pulmonary Sarcoma Arising from a Pulmonary Cyst in an Adult: A Case Report Open
Primary pulmonary sarcoma is a rare disease and is much less common than lung cancer among tumors arising from pulmonary cysts. We report the case of a female patient who showed multifocal cysts in the left S9-10. Follow-up computed tomogr…
View article: Predictive Performance of Radiomic Features Extracted from Breast MR Imaging in Postoperative Upgrading of Ductal Carcinoma <i>in Situ</i> to Invasive Carcinoma
Predictive Performance of Radiomic Features Extracted from Breast MR Imaging in Postoperative Upgrading of Ductal Carcinoma <i>in Situ</i> to Invasive Carcinoma Open
A radiomics approach using breast MRI may be a promising method for predicting the postoperative upgrade of DCIS. The present study showed that the radiomic features extracted from pre-contrast T1WI and post-contrast subtraction images in …
View article: Two cases of solitary fibrous tumor/hemangiopericytoma with different clinical features according to the World Health Organization classification: case report and review of the literature
Two cases of solitary fibrous tumor/hemangiopericytoma with different clinical features according to the World Health Organization classification: case report and review of the literature Open
Solitary fibrous tumors (SFTs) and hemangiopericytomas (HPCs) have been classified as one entity by the World Health Organization in 2016 due to gene fusion between NAB2 and STAT6. In the Central Nervous System (CNS), a hypocellular, colla…
View article: Unusual presentation of recurrent follicular lymphoma as diffuse granular shadow
Unusual presentation of recurrent follicular lymphoma as diffuse granular shadow Open
A 75‐year‐old man was diagnosed with advanced follicular lymphoma because of enlarged cervical lymph nodes. He received chemotherapy and was in complete remission for four years. However, after four years, he developed diffuse lymphadenopa…
View article: Lymphocyte-depleted classic Hodgkin lymphoma with primary extranodal disease: Two cases that highlight the combination of immunodeficiency and immune escape in the pathogenesis
Lymphocyte-depleted classic Hodgkin lymphoma with primary extranodal disease: Two cases that highlight the combination of immunodeficiency and immune escape in the pathogenesis Open
Neoplastic programmed cell death ligand 1 (PD-L1) expression, activated by PD-L1 gene alterations, is strongly associated with classic Hodgkin lymphoma (CHL). This association enabled a diagnostic consensus for lymphocyte-depleted CHL (LD-…
View article: Diagnostic utility of programmed cell death ligand 1 (clone SP142) immunohistochemistry for malignant lymphoma and lymphoproliferative disorders: A brief review
Diagnostic utility of programmed cell death ligand 1 (clone SP142) immunohistochemistry for malignant lymphoma and lymphoproliferative disorders: A brief review Open
The programmed cell death 1 (PD1)/PD1 ligand (PD-L1) axis plays an important role in tumor cell escape from immune control and has been most extensively investigated for therapeutic purposes. However, PD-L1 immunohistochemistry is still no…
View article: Frequent genetic alterations in immune checkpoint–related genes in intravascular large B-cell lymphoma
Frequent genetic alterations in immune checkpoint–related genes in intravascular large B-cell lymphoma Open
Intravascular large B-cell lymphoma (IVLBCL) is a unique type of extranodal lymphoma characterized by selective growth of tumor cells in small vessels without lymphadenopathy. Greater understanding of the molecular pathogenesis of IVLBCL i…
View article: PD‐L1 (SP142) expression in neoplastic cells predicts a poor prognosis for patients with intravascular large B‐cell lymphoma treated with rituximab‐based multi‐agent chemotherapy
PD‐L1 (SP142) expression in neoplastic cells predicts a poor prognosis for patients with intravascular large B‐cell lymphoma treated with rituximab‐based multi‐agent chemotherapy Open
Background Intravascular large B‐cell lymphoma (IVLBCL) is a rare form of diffuse large B‐cell lymphoma (DLBCL) arising in extranodal sites. PD‐L1 expression of tumor cells has been reported in IVLBCL cells, but its clinicopathological rel…
View article: LOCALIZED AMYLOIDOSIS OF THE RENAL SINUS: A CASE REPORT
LOCALIZED AMYLOIDOSIS OF THE RENAL SINUS: A CASE REPORT Open
An 80-year-old man was accidentally diagnosed with a left renal pelvic tumor by computed tomography (CT), and visited our hospital. A tumorous lesion with an inhomogeneous contrast effect occupying the left renal pelvis was confirmed by th…
View article: Five screening-detected breast cancer cases in initially disease-free BRCA1 or BRCA2 mutation carriers
Five screening-detected breast cancer cases in initially disease-free BRCA1 or BRCA2 mutation carriers Open
View article: Autopsy case report of intravascular large B-cell lymphoma with neoplastic PD-L1 expression
Autopsy case report of intravascular large B-cell lymphoma with neoplastic PD-L1 expression Open
Intravascular large B-cell lymphoma (IVLBCL) is a rare and clinically distinctive entity characterized by the almost exclusive growth of large cells within the lumen of blood vessels in particular capillaries. Reports of this peculiar dise…
View article: Granular Cell Tumor at the Hepatic Hilum Mimicking Hilar Bile Duct Carcinoma
Granular Cell Tumor at the Hepatic Hilum Mimicking Hilar Bile Duct Carcinoma Open
胆道原発顆粒細胞腫は極めてまれである．今回，我々は肝門部胆管癌と術前に鑑別困難であった肝門部胆管顆粒細胞腫の1例を経験したので報告する．症例は38歳の女性で，健診の腹部超音波検査で左肝内胆管拡張を指摘され当院へ精査目的で紹介された．腹部造影CTで肝左葉の著明な胆管拡張と左肝管に腫瘤像を認めた．ERCPで左肝管に結節型の著明な狭窄を認め，この上流側の著明な胆管拡張を認めた．生検で異型円柱上皮細胞を認め良悪性の判断はしえなかったが，肝門部胆管癌の術前診断で尾状葉合併左肝切除兼肝…
View article: Emetine elicits apoptosis of intractable B-cell lymphoma cells with <i>MYC</i> rearrangement through inhibition of glycolytic metabolism
Emetine elicits apoptosis of intractable B-cell lymphoma cells with <i>MYC</i> rearrangement through inhibition of glycolytic metabolism Open
Despite improved clinical outcomes of diffuse large B-cell lymphoma, a certain proportion of patients still develop a primary refractory disease. To overcome these lymphomas that are intractable to existing treatment strategies, the tumor …
View article: <scp>SPIB</scp> is a novel prognostic factor in diffuse large B‐cell lymphoma that mediates apoptosis via the <scp>PI</scp>3K‐<scp>AKT</scp> pathway
<span>SPIB</span> is a novel prognostic factor in diffuse large B‐cell lymphoma that mediates apoptosis via the <span>PI</span>3K‐<span>AKT</span> pathway Open
Although the clinical outcomes of diffuse large B‐cell lymphoma ( DLBCL ) have improved in the immunochemotherapy era, approximately one‐third of patients develop intractable disease. To improve clinical outcomes for these patients, it is …
View article: Adenocarcinoma arising in urinary bladder endocervicosis
Adenocarcinoma arising in urinary bladder endocervicosis Open
Endocervicosis is a rare benign condition characterized by the presence of endocervical‐type mucinous glands. Urinary bladder endocervicosis forms an elevated lesion in the posterior wall of the urinary bladder and is sometimes misdiagnose…
View article: Discovery of a drug targeting microenvironmental support for lymphoma cells by screening using patient-derived xenograft cells
Discovery of a drug targeting microenvironmental support for lymphoma cells by screening using patient-derived xenograft cells Open
View article: Engaged in Work to Deliver the Radio Waves of Television and Radio Programs
Engaged in Work to Deliver the Radio Waves of Television and Radio Programs Open