Satoko Ugai
YOU?
Author Swipe
View article: Diverging global incidence trends of early-onset cancers: comparisons with incidence trends of later-onset cancers and mortality trends of early-onset cancers
Diverging global incidence trends of early-onset cancers: comparisons with incidence trends of later-onset cancers and mortality trends of early-onset cancers Open
Background The global increase in the incidence of early-onset cancers (defined as cancers diagnosed at 20–49 years old) is a serious public health problem. We investigated 1) whether the incidence trend of early-onset cancers differs from…
View article: Unique role of the prospective cohort incident-tumor biobank method in etiological research
Unique role of the prospective cohort incident-tumor biobank method in etiological research Open
View article: Supplementary Table S2 from Associations between Calcium Intake and T-cell Infiltration in Colorectal Tumors
Supplementary Table S2 from Associations between Calcium Intake and T-cell Infiltration in Colorectal Tumors Open
Supplementary Table S2: Associations between total calcium intake and tumour infiltrating lymphocytes stratified by CASR expression in the tumour
View article: Supplementary Table S3 from Associations between Calcium Intake and T-cell Infiltration in Colorectal Tumors
Supplementary Table S3 from Associations between Calcium Intake and T-cell Infiltration in Colorectal Tumors Open
Supplementary Table S3: Associations between calcium intake and tumour infiltrating lymphocytes using inverse transformed linear regression models
View article: Supplementary Table S1 from Associations between Calcium Intake and T-cell Infiltration in Colorectal Tumors
Supplementary Table S1 from Associations between Calcium Intake and T-cell Infiltration in Colorectal Tumors Open
Supplementary Table S1: Distribution and categorization of T-cell data.
View article: Data from Associations between Calcium Intake and T-cell Infiltration in Colorectal Tumors
Data from Associations between Calcium Intake and T-cell Infiltration in Colorectal Tumors Open
Higher T-cell infiltration in colorectal tumors has been associated with better prognosis. Evidence indicates that calcium signaling is essential for T-cell functioning. However, as it is unknown whether calcium intake influences T-cell in…
View article: Supplemental Figure 3 from Density of T-cell Subsets in Colorectal Cancer in Relation to Disease-Specific Survival
Supplemental Figure 3 from Density of T-cell Subsets in Colorectal Cancer in Relation to Disease-Specific Survival Open
Supplemental Figure 3 visualizes the associations of non-overlapping T cell subset densities in epithelial and stromal tissue areas with CRC-specific survival, where hazard ratios are adjusted for age at diagnosis, sex, cancer site (proxim…
View article: Data from Density of T-cell Subsets in Colorectal Cancer in Relation to Disease-Specific Survival
Data from Density of T-cell Subsets in Colorectal Cancer in Relation to Disease-Specific Survival Open
Background:Prior studies have demonstrated that the overall density of T cells in colorectal tumors is favorably associated with colorectal cancer survival; however, few studies have considered the potentially distinct roles of heterogeneo…
View article: Supplemental Table 3 from Density of T-cell Subsets in Colorectal Cancer in Relation to Disease-Specific Survival
Supplemental Table 3 from Density of T-cell Subsets in Colorectal Cancer in Relation to Disease-Specific Survival Open
Supplemental Table 3: Participant Characteristics
View article: Supplemental Figure 2 from Density of T-cell Subsets in Colorectal Cancer in Relation to Disease-Specific Survival
Supplemental Figure 2 from Density of T-cell Subsets in Colorectal Cancer in Relation to Disease-Specific Survival Open
Supplemental Figure 2 visualizes Spearman correlations between T cell subset densities in a) epithelial tissue areas and b) in stromal tissue areas.
View article: Supplemental Table 4 from Density of T-cell Subsets in Colorectal Cancer in Relation to Disease-Specific Survival
Supplemental Table 4 from Density of T-cell Subsets in Colorectal Cancer in Relation to Disease-Specific Survival Open
Supplemental Table 4: Associations of T cell subset densities in epithelial and stromal tissue areas with CRC-specific survival, further adjusted for stage at diagnosis
View article: Supplemental Figure 1 from Density of T-cell Subsets in Colorectal Cancer in Relation to Disease-Specific Survival
Supplemental Figure 1 from Density of T-cell Subsets in Colorectal Cancer in Relation to Disease-Specific Survival Open
Supplemental Figure 1 visualizes the right-skewed distribution of naïve, memory, and regulatory CD3+CD4+ and CD3+CD8+ T cell density subsets as well as CD3- immune cells in both epithelial and stromal tissue areas.
View article: Supplemental Table 1 from Density of T-cell Subsets in Colorectal Cancer in Relation to Disease-Specific Survival
Supplemental Table 1 from Density of T-cell Subsets in Colorectal Cancer in Relation to Disease-Specific Survival Open
Supplemental Table 1: Descriptive Statistics and Categorization of T cell Subsets
View article: Supplemental Table 2 from Density of T-cell Subsets in Colorectal Cancer in Relation to Disease-Specific Survival
Supplemental Table 2 from Density of T-cell Subsets in Colorectal Cancer in Relation to Disease-Specific Survival Open
Supplemental Table 2: T cell density categorization cut points in NHS/HPFS and OFCCR
View article: Smoking habit and long-term colorectal cancer incidence by exome-wide mutational and neoantigen loads: evidence based on the prospective cohort incident-tumour biobank method
Smoking habit and long-term colorectal cancer incidence by exome-wide mutational and neoantigen loads: evidence based on the prospective cohort incident-tumour biobank method Open
Objective To test the hypothesis that the association of smoking with long-term colorectal cancer incidence may be stronger for tumours with higher mutational and neoantigen loads. Methods and analysis In the Nurses’ Health Study (1980–201…
View article: Global Incidence Trend of Early-Onset Obesity-Related and Non-Obesity-Related Cancers
Global Incidence Trend of Early-Onset Obesity-Related and Non-Obesity-Related Cancers Open
The global rise in obesity prevalence and the incidence of early-onset cancer (diagnosed between 20 and 49 years of age) is a serious public health concern. We, therefore, evaluated the recent global trends in the incidence of early-onset …
View article: Associations between Calcium Intake and T-cell Infiltration in Colorectal Tumors
Associations between Calcium Intake and T-cell Infiltration in Colorectal Tumors Open
Higher T-cell infiltration in colorectal tumors has been associated with better prognosis. Evidence indicates that calcium signaling is essential for T-cell functioning. However, as it is unknown whether calcium intake influences T-cell in…
View article: Long-term yogurt intake and colorectal cancer incidence subclassified by <i>Bifidobacterium</i> abundance in tumor
Long-term yogurt intake and colorectal cancer incidence subclassified by <i>Bifidobacterium</i> abundance in tumor Open
Evidence suggests a tumor-suppressive effect of the intake of yogurt, which typically contains Bifidobacterium. We hypothesized that long-term yogurt intake might be associated with colorectal cancer incidence differentially by tumo…
View article: 430. Tumor microbiota and tumor-infiltrating T cells in the tumor microenvironment of colorectal cancer
430. Tumor microbiota and tumor-infiltrating T cells in the tumor microenvironment of colorectal cancer Open
Background Recent studies indicate that the gut microbiota influences the immune cell infiltrates in colorectal cancer. For example, a study has shown that the amount of Fusobacterium nucleatum in colorectal carcinoma has been inversely as…
View article: Clinicopathological, molecular, and prognostic features of colorectal carcinomas with <scp><i>KRAS</i></scp> c.<scp>34G</scp>>T (p.<scp>G12C</scp>) mutation
Clinicopathological, molecular, and prognostic features of colorectal carcinomas with <span><i>KRAS</i></span> c.<span>34G</span>>T (p.<span>G12C</span>) mutation Open
Evidence indicates that combinations of anti‐EGFR antibodies and KRAS p.G12C (c.34G>T) inhibitors can be an effective treatment strategy for advanced colorectal cancer. We hypothesized that KRAS c.34G>T (p.G12C)‐mutated colorectal carcinom…
View article: Advancing precision oncology: Insights into the tumor microenvironment and immunotherapy outcomes
Advancing precision oncology: Insights into the tumor microenvironment and immunotherapy outcomes Open
View article: Enrichment of Bacteroides fragilis and enterotoxigenic Bacteroides fragilis in CpG island methylator phenotype-high colorectal carcinoma
Enrichment of Bacteroides fragilis and enterotoxigenic Bacteroides fragilis in CpG island methylator phenotype-high colorectal carcinoma Open
View article: Long-term marine ω-3 polyunsaturated fatty acids intake in relation to incidence of colorectal cancer subclassified by macrophage infiltrates
Long-term marine ω-3 polyunsaturated fatty acids intake in relation to incidence of colorectal cancer subclassified by macrophage infiltrates Open
Evidence indicates that marine omega-3 polyunsaturated fatty acid (MOPUFA) intake exerts an immunomodulatory effect to suppress the development of colorectal cancer (CRC). We hypothesized that the association of MOPUFA intake with the inci…
View article: 310. Yogurt Intake and Colorectal Cancer Incidence Subclassified by <i>Bifidobacterium S</i>tatus in Tumor
310. Yogurt Intake and Colorectal Cancer Incidence Subclassified by <i>Bifidobacterium S</i>tatus in Tumor Open
Background Although epidemiological evidence is limited, experimental data indicated a tumor-suppressive effect of yogurt containing Bifidobacterium. We hypothesized that the association between yogurt intake and colorectal cancer incidenc…
View article: 1739. Mumps Vaccine Hesitancy: Current Evidence and An Evidence-Based Campaign in Japan
1739. Mumps Vaccine Hesitancy: Current Evidence and An Evidence-Based Campaign in Japan Open
Background Mumps is still endemic in Japan because mumps vaccination is voluntary. In this study, we investigated associations of parental socioeconomic status, family structure, and knowledge/belief about mumps and mumps vaccine with pare…
View article: Inverse relationship between <i>Fusobacterium nucleatum</i> amount and tumor <scp>CD274</scp> (<scp>PD‐L1</scp>) expression in colorectal carcinoma
Inverse relationship between <i>Fusobacterium nucleatum</i> amount and tumor <span>CD274</span> (<span>PD‐L1</span>) expression in colorectal carcinoma Open
Objectives The CD274 (programmed cell death 1 ligand 1, PD‐L1)/PDCD1 (programmed cell death 1, PD‐1) immune checkpoint axis is known to regulate the antitumor immune response. Evidence also supports an immunosuppressive effect of Fusobacte…