Satoru Yonekura
YOU?
Author Swipe
View article: Exploring Patient and Public Involvement and Engagement in Allergy Research: Cross‐Disease and Cross‐Stakeholder Perspectives in Japan
Exploring Patient and Public Involvement and Engagement in Allergy Research: Cross‐Disease and Cross‐Stakeholder Perspectives in Japan Open
View article: Neutrophils predominate as IL1B-expressing cells in Schnitzler syndrome: Insights from the SCan study to evaluate the efficacy and safety of canakinumab in Japanese patients
Neutrophils predominate as IL1B-expressing cells in Schnitzler syndrome: Insights from the SCan study to evaluate the efficacy and safety of canakinumab in Japanese patients Open
This study demonstrated that the primary source of IL1B-expressing cells in SchS is neutrophils. Moreover, canakinumab improves clinical symptoms by regulating neutrophil dynamics in peripheral blood.
View article: <scp>AI</scp> ‐Based Objective Severity Assessment of Atopic Dermatitis Using Patient Photos in a Real‐World Setting: A Digital Biomarker Approach
<span>AI</span> ‐Based Objective Severity Assessment of Atopic Dermatitis Using Patient Photos in a Real‐World Setting: A Digital Biomarker Approach Open
View article: A case of dupilumab‐resistant facial erythema successfully managed with topical delgocitinib
A case of dupilumab‐resistant facial erythema successfully managed with topical delgocitinib Open
View article: Clinical factors predicting nemolizumab response in atopic dermatitis
Clinical factors predicting nemolizumab response in atopic dermatitis Open
View article: Immediate and sustained efficacy of nemolizumab in chronic pruritus of unknown origin
Immediate and sustained efficacy of nemolizumab in chronic pruritus of unknown origin Open
View article: Acetaminophen as a possible safer alternative for reducing prostaglandin E2‐major urinary metabolites concentrations and alleviating joint pain in pachydermoperiostosis
Acetaminophen as a possible safer alternative for reducing prostaglandin E2‐major urinary metabolites concentrations and alleviating joint pain in pachydermoperiostosis Open
View article: Safety and Efficacy of Prophylactic Topical Steroid Administration for Enfortumab Vedotin–related Cutaneous Toxicity
Safety and Efficacy of Prophylactic Topical Steroid Administration for Enfortumab Vedotin–related Cutaneous Toxicity Open
A drug called enfortumab vedotin (EV) used to treat advanced cancer of the urinary tract can cause severe skin reactions. We compared application of a steroid cream or Vaseline to the skin in five patients who were starting EV therapy. Thr…
View article: TARC/CCL17 reflects the severity of pemphigus (pemphigus vulgaris and pemphigus foliaceus) at the initial presentation
TARC/CCL17 reflects the severity of pemphigus (pemphigus vulgaris and pemphigus foliaceus) at the initial presentation Open
Background Pemphigus vulgaris (PV) and pemphigus foliaceus (PF) are autoimmune blistering diseases targeting desmoglein 3 (Dsg3) or desmoglein 1 (Dsg1). The current scoring system, pemphigus disease area index (PDAI), has limitations inclu…
View article: Activation of the pentose phosphate pathway in macrophages is crucial for granuloma formation in sarcoidosis
Activation of the pentose phosphate pathway in macrophages is crucial for granuloma formation in sarcoidosis Open
Sarcoidosis is a disease of unknown etiology in which granulomas form throughout the body and is typically treated with glucocorticoids, but there are no approved steroid-sparing alternatives. Here, we investigated the mechanism of granulo…
View article: A microbiota-modulated checkpoint directs immunosuppressive intestinal T cells into cancers
A microbiota-modulated checkpoint directs immunosuppressive intestinal T cells into cancers Open
Antibiotics (ABX) compromise the efficacy of programmed cell death protein 1 (PD-1) blockade in cancer patients, but the mechanisms underlying their immunosuppressive effects remain unknown. By inducing the down-regulation of mucosal addre…
View article: Recurrent cutaneous squamous cell carcinoma in the occipital scalp with clinical perineural invasion developing jugular foramen syndrome
Recurrent cutaneous squamous cell carcinoma in the occipital scalp with clinical perineural invasion developing jugular foramen syndrome Open
Perineural invasion (PNI) represents a poor prognostic factor in cases of cutaneous squamous cell carcinoma (cSCC). Microscopic or incidental PNI, detected during pathologic examination, ranges from 2.5% to 14%.1 Clinical PNI is PNI presen…
View article: Multiple Bowen's Disease on the Finger Associated with Human Papillomavirus Type 34
Multiple Bowen's Disease on the Finger Associated with Human Papillomavirus Type 34 Open
Human papillomavirus (HPV) infection has been suggested as a potential risk factor for Bowen's disease. Here, we report a case of a 40-year-old man with Bowen's disease on the finger showing a discontinuous skip lesion, in which HPV-34 was…
View article: Data from Cancer Induces a Stress Ileopathy Depending on β-Adrenergic Receptors and Promoting Dysbiosis that Contributes to Carcinogenesis
Data from Cancer Induces a Stress Ileopathy Depending on β-Adrenergic Receptors and Promoting Dysbiosis that Contributes to Carcinogenesis Open
Gut dysbiosis has been associated with intestinal and extraintestinal malignancies, but whether and how carcinogenesis drives compositional shifts of the microbiome to its own benefit remains an open conundrum. Here, we show that malignant…
View article: Data from Cancer Induces a Stress Ileopathy Depending on β-Adrenergic Receptors and Promoting Dysbiosis that Contributes to Carcinogenesis
Data from Cancer Induces a Stress Ileopathy Depending on β-Adrenergic Receptors and Promoting Dysbiosis that Contributes to Carcinogenesis Open
Gut dysbiosis has been associated with intestinal and extraintestinal malignancies, but whether and how carcinogenesis drives compositional shifts of the microbiome to its own benefit remains an open conundrum. Here, we show that malignant…
View article: Supplementary Figure from Cancer Induces a Stress Ileopathy Depending on β-Adrenergic Receptors and Promoting Dysbiosis that Contributes to Carcinogenesis
Supplementary Figure from Cancer Induces a Stress Ileopathy Depending on β-Adrenergic Receptors and Promoting Dysbiosis that Contributes to Carcinogenesis Open
Supplementary Figure from Cancer Induces a Stress Ileopathy Depending on β-Adrenergic Receptors and Promoting Dysbiosis that Contributes to Carcinogenesis
View article: Supplementary Figure from Cancer Induces a Stress Ileopathy Depending on β-Adrenergic Receptors and Promoting Dysbiosis that Contributes to Carcinogenesis
Supplementary Figure from Cancer Induces a Stress Ileopathy Depending on β-Adrenergic Receptors and Promoting Dysbiosis that Contributes to Carcinogenesis Open
Supplementary Figure from Cancer Induces a Stress Ileopathy Depending on β-Adrenergic Receptors and Promoting Dysbiosis that Contributes to Carcinogenesis
View article: Supplementary Figure from Cancer Induces a Stress Ileopathy Depending on β-Adrenergic Receptors and Promoting Dysbiosis that Contributes to Carcinogenesis
Supplementary Figure from Cancer Induces a Stress Ileopathy Depending on β-Adrenergic Receptors and Promoting Dysbiosis that Contributes to Carcinogenesis Open
Supplementary Figure from Cancer Induces a Stress Ileopathy Depending on β-Adrenergic Receptors and Promoting Dysbiosis that Contributes to Carcinogenesis
View article: Supplementary Figure from Cancer Induces a Stress Ileopathy Depending on β-Adrenergic Receptors and Promoting Dysbiosis that Contributes to Carcinogenesis
Supplementary Figure from Cancer Induces a Stress Ileopathy Depending on β-Adrenergic Receptors and Promoting Dysbiosis that Contributes to Carcinogenesis Open
Supplementary Figure from Cancer Induces a Stress Ileopathy Depending on β-Adrenergic Receptors and Promoting Dysbiosis that Contributes to Carcinogenesis
View article: Corrigendum re “Impact of Body Mass Index on Survival Outcomes for Patients with Metastatic Renal Cell Carcinoma in the Immuno-oncology Era: A Systematic Review and Meta-analysis” [Eur Urol Open Sci 2022;39:62–71]
Corrigendum re “Impact of Body Mass Index on Survival Outcomes for Patients with Metastatic Renal Cell Carcinoma in the Immuno-oncology Era: A Systematic Review and Meta-analysis” [Eur Urol Open Sci 2022;39:62–71] Open
[This corrects the article DOI: 10.1016/j.euros.2022.03.002.].
View article: 123 Anti-BP180, Pruritus, and Thymus and Activation-Regulated Chemokines as Surrogate Markers for Disease Activity in Bullous Pemphigoid
123 Anti-BP180, Pruritus, and Thymus and Activation-Regulated Chemokines as Surrogate Markers for Disease Activity in Bullous Pemphigoid Open
View article: FXYD3 Expression Predicts Poor Prognosis in Renal Cell Carcinoma with Immunosuppressive Tumor Microenvironment
FXYD3 Expression Predicts Poor Prognosis in Renal Cell Carcinoma with Immunosuppressive Tumor Microenvironment Open
FXYD3 is a protein-coding gene, belonging to the FXYD protein family associated with Na+/K+-ATPase enzymes and chloride ion channels. Accumulating evidence suggests the biological role of FXYD3 in multiple cancers. However, the prognostic …
View article: Immunohistochemical Study of Annular Erythema Appearing in a Patient with Sub-Acute Cutaneous Lupus Erythematosus
Immunohistochemical Study of Annular Erythema Appearing in a Patient with Sub-Acute Cutaneous Lupus Erythematosus Open
[Image: see text]
View article: Impact of Body Mass Index on Survival Outcomes of Patients with Metastatic Renal Cell Carcinoma in the Immuno-oncology Era: A Systematic Review and Meta-analysis
Impact of Body Mass Index on Survival Outcomes of Patients with Metastatic Renal Cell Carcinoma in the Immuno-oncology Era: A Systematic Review and Meta-analysis Open
View article: Immune system and intestinal microbiota determine efficacy of androgen deprivation therapy against prostate cancer
Immune system and intestinal microbiota determine efficacy of androgen deprivation therapy against prostate cancer Open
Background Prostate cancer (PC) responds to androgen deprivation therapy (ADT) usually in a transient fashion, progressing from hormone-sensitive PC (HSPC) to castration-resistant PC (CRPC). We investigated a mouse model of PC as well as s…
View article: Epstein-Barr Virus-induced Gene 3 as a Novel Biomarker in Metastatic Melanoma With Infiltrating CD8<sup>+</sup>T Cells: A Study Based on The Cancer Genome Atlas (TCGA)
Epstein-Barr Virus-induced Gene 3 as a Novel Biomarker in Metastatic Melanoma With Infiltrating CD8<sup>+</sup>T Cells: A Study Based on The Cancer Genome Atlas (TCGA) Open
EBI3 could serve as a novel biomarker in metastatic melanoma with a favorable TILs profile.
View article: EVI2B Is a New Prognostic Biomarker in Metastatic Melanoma with IFNgamma Associated Immune Infiltration
EVI2B Is a New Prognostic Biomarker in Metastatic Melanoma with IFNgamma Associated Immune Infiltration Open
Background: To assess the prognostic role and the antitumor immunological relevance of ecotropic viral integration site 2B (EVI2B) in metastatic melanoma. Methods: In this study, we integrated clinical data, mRNA expression data, and the d…
View article: Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade
Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade Open
View article: Multifaceted modes of action of the anticancer probiotic Enterococcus hirae
Multifaceted modes of action of the anticancer probiotic Enterococcus hirae Open
View article: Resolving the Paradox of Colon Cancer Through the Integration of Genetics, Immunology, and the Microbiota
Resolving the Paradox of Colon Cancer Through the Integration of Genetics, Immunology, and the Microbiota Open
While colorectal cancers (CRC) are paradigmatic tumors invaded by effector memory lymphocytes, the mechanisms accounting for the relative resistance of MSI negative CRC to immunogenic cell death mediated by oxaliplatin and immune checkpoin…