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View article: Serum Paraoxonase-1 (PON-1) in Dogs: Frequency of Decreased Values in Clinical Practice and Prognostic Significance
Serum Paraoxonase-1 (PON-1) in Dogs: Frequency of Decreased Values in Clinical Practice and Prognostic Significance Open
Serum activity of paraoxonase-1 (PON-1) decreases in canine inflammation. This study aimed to evaluate how frequently PON-1 activity is reduced across different disease categories and to assess its potential prognostic significance. PON-1 …
View article: Antitumor Efficacy and Immunomodulation of H-Ferritin Nanocaged Doxorubicin for Triple Negative Breast Cancer
Antitumor Efficacy and Immunomodulation of H-Ferritin Nanocaged Doxorubicin for Triple Negative Breast Cancer Open
View article: Corrigendum to “Chronic cholesterol administration to the brain supports complete and long-lasting cognitive and motor amelioration in Huntington’s disease” [Pharmacol. Res. 194 (2023) 106823]
Corrigendum to “Chronic cholesterol administration to the brain supports complete and long-lasting cognitive and motor amelioration in Huntington’s disease” [Pharmacol. Res. 194 (2023) 106823] Open
View article: Serum TNF-Alpha and IL-10 Predict Reduced Sensitivity to Fear- and Anxiety-Related Traits in Healthy Older Dogs: Preliminary Evidence for Immune–Personality Signatures in Later Life
Serum TNF-Alpha and IL-10 Predict Reduced Sensitivity to Fear- and Anxiety-Related Traits in Healthy Older Dogs: Preliminary Evidence for Immune–Personality Signatures in Later Life Open
As dogs live longer, they face an increased risk of functional age-related changes, including physiological and behavioral alterations. However, data on these age-related processes in domestic dogs remain limited. In this study, we assesse…
View article: Clinical and Clinico-Pathological Observations of the Erythrocyte Sedimentation Rate in Dogs Affected by Leishmaniosis and Monitored During Antileishmanial Treatment
Clinical and Clinico-Pathological Observations of the Erythrocyte Sedimentation Rate in Dogs Affected by Leishmaniosis and Monitored During Antileishmanial Treatment Open
The erythrocyte sedimentation rate (ESR) is used in canine medicine in several disorders, especially to evaluate the levels of inflammation. ESR is a valid inflammatory marker in canine leishmaniosis (CanL), being markedly increased in sic…
View article: Pre and post fibrate supplementation lipoprotein electrophoresis in hyperlipemic dogs with biliary tree disease
Pre and post fibrate supplementation lipoprotein electrophoresis in hyperlipemic dogs with biliary tree disease Open
View article: The Erythrocyte Sedimentation Rate (ESR) in Veterinary Medicine: A Focused Review in Dogs and Cats
The Erythrocyte Sedimentation Rate (ESR) in Veterinary Medicine: A Focused Review in Dogs and Cats Open
The erythrocyte sedimentation rate (ESR) measures the rate at which erythrocytes aggregate and sediment in a fixed time in an anticoagulated blood tube and is expressed as a speed (mm/h). The ESR is still widely used in human medicine main…
View article: Lactate Dehydrogenase Isoenzymes in Serum and Effusion of Cats with Felineinfectious Peritonitis Compared with Cats with Other Effusive Diseases
Lactate Dehydrogenase Isoenzymes in Serum and Effusion of Cats with Felineinfectious Peritonitis Compared with Cats with Other Effusive Diseases Open
View article: Comparative Evaluation of Lipid Profile, C-Reactive Protein and Paraoxonase-1 Activity in Dogs with Inflammatory Protein-Losing Enteropathy and Healthy Dogs
Comparative Evaluation of Lipid Profile, C-Reactive Protein and Paraoxonase-1 Activity in Dogs with Inflammatory Protein-Losing Enteropathy and Healthy Dogs Open
Chronic inflammation alters lipoprotein metabolism and causes changes in the serum concentrations of lipids, C-reactive protein (CRP), and paraoxonase-1 activity (PON-1), an enzyme that may act as a local detoxifier, antioxidant, and immun…
View article: Comparative Evaluation of Lipid Profile, C-reactive Protein and Paraoxonase-1 Activity in Dogs with Inflammatory Protein-Losing Enteropathy and Healthy Dogs
Comparative Evaluation of Lipid Profile, C-reactive Protein and Paraoxonase-1 Activity in Dogs with Inflammatory Protein-Losing Enteropathy and Healthy Dogs Open
Chronic inflammation alters lipoprotein metabolism and causes changes in serum concentrations of lipids, C-reactive protein (CRP), and paraoxonase-1 activity (PON-1), an enzyme, which in the gastrointestinal tract may act as a local detoxi…
View article: The use of serum paraoxonase‐1 to assess inflammation in horses with colitis
The use of serum paraoxonase‐1 to assess inflammation in horses with colitis Open
Background Paraoxonase‐1 (PON‐1) has been suggested as a marker of inflammation and oxidative stress in horses and could potentially be used for prognostication in horses with colitis. Objectives Assessment of PON‐1 in horses with colitis …
View article: Diagnosis of Septic Body Cavity Effusion in Dogs and Cats: Cytology vs. Bacterial Culture
Diagnosis of Septic Body Cavity Effusion in Dogs and Cats: Cytology vs. Bacterial Culture Open
The elective test for the determination of the effusions etiopathogenesis is represented by physico-chemical analysis and cytology. Nevertheless, the bacterial culture and antibiotic sensitivity tests are crucial for setting therapy and fo…
View article: Clinicopathological and Molecular Analysis of Aqueous Humor for the Diagnosis of Feline Infectious Peritonitis
Clinicopathological and Molecular Analysis of Aqueous Humor for the Diagnosis of Feline Infectious Peritonitis Open
Background: This study was designed to assess the diagnostic utility for FIP of cytology, protein measurement and RT-PCR for feline coronaviruses (FCoV) on aqueous humor (AH), since little information is currently available. Methods: AH sa…
View article: Increased Erythrocyte Sedimentation Rate in Dogs: Frequency in Routine Clinical Practice and Association with Hematological Changes
Increased Erythrocyte Sedimentation Rate in Dogs: Frequency in Routine Clinical Practice and Association with Hematological Changes Open
(1) Background: the erythrocyte sedimentation rate (ESR) has been reported to increase in some infectious or inflammatory diseases in dogs, but no information on the frequency of increases in a routine clinical setting exists. The aim of t…
View article: Measurement of Feline Alpha-1 Acid Glycoprotein in Serum and Effusion Using an ELISA Method: Analytical Validation and Diagnostic Role for Feline Infectious Peritonitis
Measurement of Feline Alpha-1 Acid Glycoprotein in Serum and Effusion Using an ELISA Method: Analytical Validation and Diagnostic Role for Feline Infectious Peritonitis Open
Background: Alpha-1 acid glycoprotein (AGP) may support a clinical diagnosis of feline infectious peritonitis (FIP). In this study, we assessed the analytical and diagnostic performances of a novel ELISA method to measure feline AGP. Metho…
View article: Clinical and Clinico-Pathological Observations of the Erythrocyte Sedimentation Rate in Dogs Affected by Leishmaniosis and Other Inflammatory Diseases
Clinical and Clinico-Pathological Observations of the Erythrocyte Sedimentation Rate in Dogs Affected by Leishmaniosis and Other Inflammatory Diseases Open
The erythrocyte sedimentation rate (ESR) has been used in canine medicine in several disorders, above all, to evaluate levels of inflammation. This study evaluated the ESR in canine leishmaniosis (CanL) and other inflammatory conditions. T…
View article: Blood gases, acid‐base, and metabolic alterations in calves with bronchopneumonia diagnosed via clinical signs and thoracic ultrasonography: A cross‐sectional study
Blood gases, acid‐base, and metabolic alterations in calves with bronchopneumonia diagnosed via clinical signs and thoracic ultrasonography: A cross‐sectional study Open
Background Bronchopneumonia (BP) in calves potentially causes systemic changes. Objectives To describe metabolic, arterial blood gas, and acid‐base disorders in calves with BP diagnosed by thoracic ultrasound (TUS), Wisconsin score (WISC),…
View article: Automated hematological cell count using sysmex XN-1000V in Testudo hermanni: Agreement with manual count
Automated hematological cell count using sysmex XN-1000V in Testudo hermanni: Agreement with manual count Open
View article: Preclinical pharmacology of patient-derived extracellular vesicles for the intraoperative imaging of tumors
Preclinical pharmacology of patient-derived extracellular vesicles for the intraoperative imaging of tumors Open
Extracellular vesicles (EVs) derived from the plasma of oncological patients exhibit significant tumor-targeting properties, unlike those from healthy individuals. We have previously shown the feasibility of formulating the near-infrared (…
View article: Prospective Application of the Erythrocyte Sedimentation Rate (ESR) as a Possible Inflammatory Marker in Feline Patients
Prospective Application of the Erythrocyte Sedimentation Rate (ESR) as a Possible Inflammatory Marker in Feline Patients Open
The application of the erythrocyte sedimentation rate (ESR) in feline medicine is currently unavailable, while in canine medicine it has been rediscovered due to the introduction of an automated ESR device. Our aims were to (1) define the …
View article: Lipoprotein profiles in Miniature Schnauzer dogs with idiopathic hypertriglyceridemia and hypercortisolism
Lipoprotein profiles in Miniature Schnauzer dogs with idiopathic hypertriglyceridemia and hypercortisolism Open
Miniature Schnauzer dogs (MSs) are predisposed to both idiopathic hypertriglyceridemia (iHTG) and hypercortisolism (HCort). To our knowledge, the lipoprotein profiles of MSs with iHTG have not been compared to those with HCort. We analyzed…
View article: Chitinase-1 Activity in Serum of Cats with FIP
Chitinase-1 Activity in Serum of Cats with FIP Open
Background: Chitotriosidase (chitinase 1 or CHIT1) is secreted by activated macrophages. Macrophages are involved in the pathogenesis of feline infectious peritonitis (FIP). No reports on CHIT1 activity in cats with FIP are available. Obje…
View article: Fecal Carriage of Extended-Spectrum β-Lactamase-/AmpC-Producing Escherichia coli in Pet and Stray Cats
Fecal Carriage of Extended-Spectrum β-Lactamase-/AmpC-Producing Escherichia coli in Pet and Stray Cats Open
Dogs have been reported as potential carriers of antimicrobial-resistant bacteria, but the role of cats has been poorly studied. The aim of this study was to investigate the presence and the risk factors associated with the fecal carriage …
View article: Detection and genetic characterization of domestic cat hepadnavirus in cats with cavitary effusions
Detection and genetic characterization of domestic cat hepadnavirus in cats with cavitary effusions Open
After the identification of the novel domestic cat hepadnavirus (DCH) in 2018, its potential pathogenetic role in feline hepatic diseases has been suggested. Following the detection of DCH in a cat's serum and peritoneal effusion, the aim …
View article: Chronic cholesterol administration to the brain supports complete and long-lasting cognitive and motor amelioration in Huntington’s disease
Chronic cholesterol administration to the brain supports complete and long-lasting cognitive and motor amelioration in Huntington’s disease Open
View article: Assessment of circulating immune complexes in canine leishmaniosis and dirofilariosis
Assessment of circulating immune complexes in canine leishmaniosis and dirofilariosis Open
View article: Comparison of diagnostic performances of different serological tests for SARS‐CoV‐2 antibody detection in cats and dogs
Comparison of diagnostic performances of different serological tests for SARS‐CoV‐2 antibody detection in cats and dogs Open
Serosurveillance among animals, including pets, plays an important role in the current coronavirus disease 2019 (COVID-19) pandemic, because severe acute respiratory coronavirus 2 (SARS-CoV-2) infections in animal populations could result …
View article: Utility of the Ratio between Lactate Dehydrogenase (LDH) Activity and Total Nucleated Cell Counts in Effusions (LDH/TNCC Ratio) for the Diagnosis of Feline Infectious Peritonitis (FIP)
Utility of the Ratio between Lactate Dehydrogenase (LDH) Activity and Total Nucleated Cell Counts in Effusions (LDH/TNCC Ratio) for the Diagnosis of Feline Infectious Peritonitis (FIP) Open
Background: We tested the hypothesis that the ratio between lactate dehydrogenase activity (LDH) and total nucleated cell counts (TNCC) in effusions may be useful to diagnose feline infectious peritonitis (FIP). Methods: LDH/TNCC ratio was…
View article: Chronic cholesterol administration to the brain supports complete and long-lasting cognitive and motor amelioration in Huntington’s disease
Chronic cholesterol administration to the brain supports complete and long-lasting cognitive and motor amelioration in Huntington’s disease Open
Evidence that Huntington’s disease (HD) is characterized by impaired cholesterol biosynthesis in the brain has led to strategies to increase its level in the brain of the rapidly progressing R6/2 mouse model, with a positive therapeutic ou…
View article: Molecular Detection of Feline Coronavirus in Captive Non-Domestic Felids from Zoological Facilities
Molecular Detection of Feline Coronavirus in Captive Non-Domestic Felids from Zoological Facilities Open
Cases of feline infectious peritonitis (FIP), a disease with a high mortality rate caused by the feline coronavirus (FCoV), have been reported in non-domestic felids, highlighting the need for surveys of FCoV in these endangered species. W…