Saviana Gandolfo
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View article: ABS0849 GREATER SALIVARY GLAND INFLAMMATION IN PEDIATRIC SJÖGREN'S DISEASE COMPARED TO ADULTS: HISTOLOGICAL EVIDENCE
ABS0849 GREATER SALIVARY GLAND INFLAMMATION IN PEDIATRIC SJÖGREN'S DISEASE COMPARED TO ADULTS: HISTOLOGICAL EVIDENCE Open
View article: POS0489 UNDERSTANDING FATIGUE THROUGH PATIENTS' EYES: DEVELOPMENT OF A NOVEL QUESTIONNAIRE CAPTURING THE COMPLEXITY OF REAL-LIFE FATIGUE IN SJÖGREN'S DISEASE
POS0489 UNDERSTANDING FATIGUE THROUGH PATIENTS' EYES: DEVELOPMENT OF A NOVEL QUESTIONNAIRE CAPTURING THE COMPLEXITY OF REAL-LIFE FATIGUE IN SJÖGREN'S DISEASE Open
View article: The effect of anti-TNF drugs on the intestinal microbiota in patients with spondyloarthritis, rheumatoid arthritis, and inflammatory bowel diseases
The effect of anti-TNF drugs on the intestinal microbiota in patients with spondyloarthritis, rheumatoid arthritis, and inflammatory bowel diseases Open
Spondyloarthritis (SpA), rheumatoid arthritis (RA), and inflammatory bowel diseases (IBD) are chronic inflammatory autoimmune diseases that are associated with alterations in the composition of the intestinal microbiota ( i.e ., dysbiosis)…
View article: Seronegative rheumatoid arthritis: one year in review 2023
Seronegative rheumatoid arthritis: one year in review 2023 Open
In the past 20 years, earlier diagnosis and more intensive management have considerably improved the prognosis of rheumatoid arthritis (RA), with milder disease course achieved in particular in seropositive patients. In contrast, seronegat…
View article: JAK/STAT pathway targeting in primary Sjögren syndrome
JAK/STAT pathway targeting in primary Sjögren syndrome Open
Primary Sjögren's syndrome (pSS) is an autoimmune systemic disease mainly affecting exocrine glands and resulting in disabling symptoms, as dry eye and dry mouth. Mechanisms underlying pSS pathogenesis are intricate, involving multiplanar …
View article: Characterization and outcomes of 414 patients with primary SS who developed haematological malignancies
Characterization and outcomes of 414 patients with primary SS who developed haematological malignancies Open
Objective To characterize 414 patients with primary SS who developed haematological malignancies and to analyse how the main SS- and lymphoma-related features can modify the presentation patterns and outcomes. Methods By January 2021, the …
View article: Addressing the clinical unmet needs in primary Sjögren’s Syndrome through the sharing, harmonization and federated analysis of 21 European cohorts
Addressing the clinical unmet needs in primary Sjögren’s Syndrome through the sharing, harmonization and federated analysis of 21 European cohorts Open
View article: Maladaptive Autophagy in the Pathogenesis of Autoimmune Epithelitis in Sjögren's Syndrome
Maladaptive Autophagy in the Pathogenesis of Autoimmune Epithelitis in Sjögren's Syndrome Open
Objective Salivary gland epithelial cells (SGECs) are key cellular drivers in the pathogenesis of primary Sjögren's syndrome (SS); however, the mechanisms sustaining SGEC activation in primary SS remain unclear. We undertook this study to …
View article: Shared Pathogenetic Features Between Common Variable Immunodeficiency and Sjögren’s Syndrome: Clues for a Personalized Medicine
Shared Pathogenetic Features Between Common Variable Immunodeficiency and Sjögren’s Syndrome: Clues for a Personalized Medicine Open
Common variable immunodeficiency disorders (CVID) are a group of rare diseases of the immune system and the most common symptomatic primary antibody deficiency in adults. The “variable” aspect of CVID refers to the approximately half of th…
View article: A biomarker for lymphoma development in Sjogren's syndrome: Salivary gland focus score
A biomarker for lymphoma development in Sjogren's syndrome: Salivary gland focus score Open
View article: Peripheral Nervous System Involvement in Sjögren’s Syndrome: Analysis of a Cohort From the Italian Research Group on Sjögren’s Syndrome
Peripheral Nervous System Involvement in Sjögren’s Syndrome: Analysis of a Cohort From the Italian Research Group on Sjögren’s Syndrome Open
Purpose The prevalence of peripheral nervous system (PNS) involvement in primary Sjögren’s syndrome (pSS) has been reported to range from 2% to over 50%. Bias in study designs, including low number of patients and unclearly defined rheumat…
View article: Ultrasound and Bioptic Investigation of Patients with Primary Sjögren’s Syndrome
Ultrasound and Bioptic Investigation of Patients with Primary Sjögren’s Syndrome Open
Primary Sjögren’s syndrome (pSS) is a chronic and heterogeneous disorder characterized by a wide spectrum of glandular and extra-glandular features. The hallmark of pSS is considered to be the immune-mediated involvement of the exocrine gl…
View article: Childhood-onset of primary Sjögren’s syndrome: phenotypic characterization at diagnosis of 158 children
Childhood-onset of primary Sjögren’s syndrome: phenotypic characterization at diagnosis of 158 children Open
Objectives To characterize the phenotypic presentation at diagnosis of childhood-onset primary SS. Methods The Big Data Sjögren Project Consortium is an international, multicentre registry using worldwide data-sharing cooperative merging o…
View article: TREX1 variants in Sjogren's syndrome related lymphomagenesis
TREX1 variants in Sjogren's syndrome related lymphomagenesis Open
Genetic variants of the three-prime repair exonuclease 1 (TREX1) -an exonuclease involved in DNA repair and degradation- have been previously found to increase susceptibility to Aicardi Goutieres syndrome, familial chilblain lupus and syst…
View article: SARS-CoV-2 infection in patients with primary Sjögren syndrome: characterization and outcomes of 51 patients
SARS-CoV-2 infection in patients with primary Sjögren syndrome: characterization and outcomes of 51 patients Open
Objective To analyse the prognosis and outcomes of SARS-CoV-2 infection in patients with primary SS. Methods We searched for patients with primary SS presenting with SARS-CoV-2 infection (defined following and according to the European Cen…
View article: Primary Sjögren’s Syndrome of Early and Late Onset: Distinct Clinical Phenotypes and Lymphoma Development
Primary Sjögren’s Syndrome of Early and Late Onset: Distinct Clinical Phenotypes and Lymphoma Development Open
Patients with early and late disease onset constitute a significant proportion of pSS population with distinct clinical phenotypes. They possess a higher prevalence of lymphoma, with different predisposing factors and lymphoma distribution…
View article: Sjögren’s Syndrome: The Clinical Spectrum of Male Patients
Sjögren’s Syndrome: The Clinical Spectrum of Male Patients Open
Background: To compare the clinical, serological and histologic features between male and female patients with Sjögren’s syndrome (SS) and explore the potential effect of gender on lymphoma development. Methods: From a multicenter populati…
View article: Cryoglobulinemic vasculitis in primary Sjögren's Syndrome: Clinical presentation, association with lymphoma and comparison with Hepatitis C-related disease
Cryoglobulinemic vasculitis in primary Sjögren's Syndrome: Clinical presentation, association with lymphoma and comparison with Hepatitis C-related disease Open
View article: FRI0149 THE CLINICAL FEATURES OF SJÖGREN'S SYNDROME PATIENTS WITH EARLY AND LATE DISEASE ONSET
FRI0149 THE CLINICAL FEATURES OF SJÖGREN'S SYNDROME PATIENTS WITH EARLY AND LATE DISEASE ONSET Open
View article: THU0294 THE DIFFERENCES IN THE CLINICAL SPECTRUM OF CRYOGLOBULINEMIC VASCULITIS BETWEEN SJÖGREN'S SYNDROME AND HCV HEPATITIS
THU0294 THE DIFFERENCES IN THE CLINICAL SPECTRUM OF CRYOGLOBULINEMIC VASCULITIS BETWEEN SJÖGREN'S SYNDROME AND HCV HEPATITIS Open
View article: Childhood-onset of primary Sjogren syndrome Phenotypic characterization at diagnosis of 158 children
Childhood-onset of primary Sjogren syndrome Phenotypic characterization at diagnosis of 158 children Open
OBJECTIVES. To characterize the phenotypic presentation at diagnosis of childhood-onset primary Sjogren syndrome (SjS). METHODS. The Big Data Sjogren Project Consortium is an international, multicentre registry using worldwide data-sharing…
View article: Overcoming the Barriers That Obscure the Interlinking and Analysis of Clinical Data Through Harmonization and Incremental Learning
Overcoming the Barriers That Obscure the Interlinking and Analysis of Clinical Data Through Harmonization and Incremental Learning Open
Goal: To present a framework for data sharing, curation, harmonization and federated data analytics to solve open issues in healthcare, such as, the development of robust disease prediction models. Methods: Data curation is a…
View article: Predicting lymphoma development in patients with Sjögren’s syndrome
Predicting lymphoma development in patients with Sjögren’s syndrome Open
Publication in the conference proceedings of EUSIPCO, Lisbon, Portugal, 2014
View article: Articular and Peripheral Nervous System Involvement Are Linked to the Long-Term Outcome in Primary Sjögren's Syndrome: The Relevance of Single Organ Manifestations Rather Than a Composite Score as Predictors
Articular and Peripheral Nervous System Involvement Are Linked to the Long-Term Outcome in Primary Sjögren's Syndrome: The Relevance of Single Organ Manifestations Rather Than a Composite Score as Predictors Open
Objective: The disease course in primary Sjögren's Syndrome (pSS) differs in different subsets of patients. The aim of this study was to clarify whether the pattern of organ involvement may improve the prediction of the very long-te…
View article: THU0217 SERUM THYMIC STROMAL LYMPHOPOIETIN (TSLP) AS A BIOMARKER OF B-CELL LYMPHOPROLIFERATION IN SJÖGREN'S SYNDROME
THU0217 SERUM THYMIC STROMAL LYMPHOPOIETIN (TSLP) AS A BIOMARKER OF B-CELL LYMPHOPROLIFERATION IN SJÖGREN'S SYNDROME Open
View article: AB0166 ENHANCING THE QUALITY OF CLINICAL DATA THROUGH DATA CURATION IN PRIMARY SJöGREN'S SYNDROME
AB0166 ENHANCING THE QUALITY OF CLINICAL DATA THROUGH DATA CURATION IN PRIMARY SJöGREN'S SYNDROME Open
View article: THU0262 FATIGUE IN PRIMARY SJÖGREN'S SYNDROME AS A DISEASE MANIFESTATION REFLECTING THE DEGREE OF MUCOSA-ASSOCIATED LYMPHOID TISSUE (MALT) INVOLVEMENT
THU0262 FATIGUE IN PRIMARY SJÖGREN'S SYNDROME AS A DISEASE MANIFESTATION REFLECTING THE DEGREE OF MUCOSA-ASSOCIATED LYMPHOID TISSUE (MALT) INVOLVEMENT Open
View article: SAT0207 DEVELOPMENT OF QUESTIONNAIRES TO ASSESS HEALTHCARE UTILIZATION AND ACCESS IN PATIENTSWITH PRIMARY SJöGREN'S SYNDROME AT THE DIAGNOSIS AND DURING THE DISEASE COURSE
SAT0207 DEVELOPMENT OF QUESTIONNAIRES TO ASSESS HEALTHCARE UTILIZATION AND ACCESS IN PATIENTSWITH PRIMARY SJöGREN'S SYNDROME AT THE DIAGNOSIS AND DURING THE DISEASE COURSE Open
View article: SAT0190 LYMPHOMA IN PRIMARY SJÖGREN'S SYNDROME: A RETROSPECTIVE CLINICAL STUDY WITH PATIENTS FROM THE UPA (UDINE, PISA, ATHENS) GROUP
SAT0190 LYMPHOMA IN PRIMARY SJÖGREN'S SYNDROME: A RETROSPECTIVE CLINICAL STUDY WITH PATIENTS FROM THE UPA (UDINE, PISA, ATHENS) GROUP Open
View article: FRI0288 Thymic stromal lymphopoietin (TSLP) biological effects on human peripheral blood b lymphocytes in primary sjÖgren's syndrome
FRI0288 Thymic stromal lymphopoietin (TSLP) biological effects on human peripheral blood b lymphocytes in primary sjÖgren's syndrome Open