Explanipedia

Whole Slide Imaging in Genitourinary Pathology:A Cloud-Based Digitisation Workflow for Resource-Limited Settings Open

Aisha Memon, Talat Zehra, Anil V. Parwani, Saad Nadeem · 2025

Digitisation, Genitourinary pathology, Image interpretation, Telepathology.

DIAGNOSTIC ACCURACY OF FOCUSED ABDOMINAL SONOGRAPHY IN GRADING HEPATIC TRAUMA KEEPING CECT ABDOMEN AS GOLD STANDARD Open

Mamoon Rasheed, Saad Nadeem, Saira Ahmed, Aasma Shaheen, Mohamad Iqbal , et al. · 2025

Background: Hepatic trauma remains one of the most frequent and severe abdominal injuries associated with considerable morbidity and mortality in trauma care. Rapid, reliable, and non-invasive diagnostic approaches are essential to improve…

Neuropharmacology of Neuropathic Pain: A Systematic Review Open

Muhammad Umar Mian, Mishal Afzal, Aqsa A Butt, Muniba Ijaz, Kashaf Khalil , et al. · 2024

Neuropathic pain, a debilitating condition, remains challenging to manage effectively. An insight into neuropharmacological mechanisms is critical for optimizing treatment strategies. This systematic review aims to evaluate the role of neu…

Rethinking Histology Slide Digitization Workflows for Low-Resource Settings Open

Talat Zehra, Joseph P. Marino, Wendy Wang, Grigoriy Frantsuzov, Saad Nadeem · 2024

Histology slide digitization is becoming essential for telepathology (remote consultation), knowledge sharing (education), and using the state-of-the-art artificial intelligence algorithms (augmented/automated end-to-end clinical workflows…

Rethinking Histology Slide Digitization Workflows for Low-Resource Settings Open

Talat Zehra, Joseph P. Marino, Wendy Wang, Grigoriy Frantsuzov, Saad Nadeem · 2024

Exploring published and novel pre-treatment CT and PET radiomics to stratify risk of progression among early-stage non-small cell lung cancer patients treated with stereotactic radiation Open

Maria Thor, Kelly Fitzgerald, Aditya Apte, Jung Hun Oh, Aditi Iyer , et al. · 2023

Vis-SPLIT: Interactive Hierarchical Modeling for mRNA Expression Classification Open

Braden Roper, James C. Mathews, Saad Nadeem, Ji Hwan Park · 2023

We propose an interactive visual analytics tool, Vis-SPLIT, for partitioning a population of individuals into groups with similar gene signatures. Vis-SPLIT allows users to interactively explore a dataset and exploit visual separations to …

RT-GAN: Recurrent Temporal GAN for Adding Lightweight Temporal Consistency to Frame-Based Domain Translation Approaches Open

Shawn Mathew, Saad Nadeem, Alvin C. Goh, Arie Kaufman · 2023

Fourteen million colonoscopies are performed annually just in the U.S. However, the videos from these colonoscopies are not saved due to storage constraints (each video from a high-definition colonoscope camera can be in tens of gigabytes)…

Ki67 proliferation index in medullary thyroid carcinoma: a comparative study of multiple counting methods and validation of image analysis and deep learning platforms Open

Saad Nadeem, Matthew G. Hanna, Kartik Viswanathan, Joseph P. Marino, Mahsa Ahadi , et al. · 2023

Aims The International Medullary Thyroid Carcinoma Grading System, introduced in 2022, mandates evaluation of the Ki67 proliferation index to assign a histological grade for medullary thyroid carcinoma. However, manual counting remains a t…

Vis-SPLIT: Interactive Hierarchical Modeling for mRNA Expression Classification Open

Braden Roper, James C. Mathews, Saad Nadeem, Ji Hwan Park · 2023

We propose an interactive visual analytics tool, Vis-SPLIT, for partitioning a population of individuals into groups with similar gene signatures. Vis-SPLIT allows users to interactively explore a dataset and exploit visual separations to …

Integration of peripheral blood‐ and tissue‐based biomarkers of response to immune checkpoint blockade in urothelial carcinoma Open

R. Vanguri, James W. Smithy, Yanyun Li, Mingqiang Zhuang, Colleen Maher , et al. · 2023

As predictive biomarkers of response to immune checkpoint inhibitors (ICIs) remain a major unmet clinical need in patients with urothelial carcinoma (UC), we sought to identify tissue‐based immune biomarkers of clinical benefit to ICIs usi…

An AI-Ready Multiplex Staining Dataset for Reproducible and Accurate Characterization of Tumor Immune Microenvironment Open

Parmida Ghahremani, Joseph P. Marino, Juan C. Hernandez‐Prera, Janis V. de la Iglesia, Robbert J.C. Slebos , et al. · 2023

We introduce a new AI-ready computational pathology dataset containing restained and co-registered digitized images from eight head-and-neck squamous cell carcinoma patients. Specifically, the same tumor sections were stained with the expe…

Supplementary Data from Tumor MHC Class I Expression Associates with Intralesional IL2 Response in Melanoma Open