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View article: Author response: C-C chemokine receptor 4 deficiency exacerbates early atherosclerosis in mice
Author response: C-C chemokine receptor 4 deficiency exacerbates early atherosclerosis in mice Open
View article: Disruption of small intestinal mucosal homeostasis in mice with amiodarone induced steatohepatitis
Disruption of small intestinal mucosal homeostasis in mice with amiodarone induced steatohepatitis Open
View article: C-C chemokine receptor 4 deficiency exacerbates early atherosclerosis in mice
C-C chemokine receptor 4 deficiency exacerbates early atherosclerosis in mice Open
Chronic inflammation via dysregulation of T cell immune responses is critically involved in the pathogenesis of atherosclerotic cardiovascular disease. Improving the balance between proinflammatory T cells and anti-inflammatory regulatory …
View article: Unilateral upper lung field pulmonary fibrosis after primary lung cancer surgery as a late complication to be recognized
Unilateral upper lung field pulmonary fibrosis after primary lung cancer surgery as a late complication to be recognized Open
Objective Unilateral upper lung field pulmonary fibrosis (UPF) is a possible complication on the operated side after lung cancer surgery. However, its incidence and associated perioperative factors remain unclear. This study investigated t…
View article: Author response: C-C chemokine receptor 4 deficiency exacerbates early atherosclerosis in mice
Author response: C-C chemokine receptor 4 deficiency exacerbates early atherosclerosis in mice Open
View article: C-C chemokine receptor 4 deficiency exacerbates early atherosclerosis in mice
C-C chemokine receptor 4 deficiency exacerbates early atherosclerosis in mice Open
Chronic inflammation via dysregulation of T cell immune responses is critically involved in the pathogenesis of atherosclerotic cardiovascular disease. Improving the balance between proinflammatory T cells and anti-inflammatory regulatory …
View article: 312 nm UVB Phototherapy Limits Atherosclerosis by Regulating Immunoinflammatory Responses in Mice.
312 nm UVB Phototherapy Limits Atherosclerosis by Regulating Immunoinflammatory Responses in Mice. Open
We demonstrated that 312 nm UVB irradiation limits atherosclerosis by favorably modulating the T cell balance and lipid mediator profile. Our findings indicate that 312 nm UVB phototherapy could be an attractive immunomodulatory approach f…
View article: Author response: C-C chemokine receptor 4 deficiency exacerbates early atherosclerosis in mice
Author response: C-C chemokine receptor 4 deficiency exacerbates early atherosclerosis in mice Open
View article: C-C chemokine receptor 4 deficiency exacerbates early atherosclerosis in mice
C-C chemokine receptor 4 deficiency exacerbates early atherosclerosis in mice Open
Chronic inflammation via dysregulation of T cell immune responses is critically involved in the pathogenesis of atherosclerotic cardiovascular disease. Improving the balance between proinflammatory T cells and anti-inflammatory regulatory …
View article: C-C chemokine receptor 4 deficiency exacerbates early atherosclerosis in mice
C-C chemokine receptor 4 deficiency exacerbates early atherosclerosis in mice Open
Chronic inflammation via dysregulation of T cell immune responses is critically involved in the pathogenesis of atherosclerotic cardiovascular disease. Improving the balance between proinflammatory T cells and anti-inflammatory regulatory …
View article: C-C chemokine receptor 4 deficiency exacerbates early atherosclerosis in mice
C-C chemokine receptor 4 deficiency exacerbates early atherosclerosis in mice Open
Chronic inflammation via dysregulation of T cell immune responses is critically involved in the pathogenesis of atherosclerotic cardiovascular disease. Improving the balance between proinflammatory T cells and anti-inflammatory regulatory …
View article: C-C chemokine receptor 4 deficiency exacerbates early atherosclerosis in mice
C-C chemokine receptor 4 deficiency exacerbates early atherosclerosis in mice Open
Chronic inflammation via dysregulation of T cell immune responses is critically involved in the pathogenesis of atherosclerotic cardiovascular disease. Improving the balance between proinflammatory T cells and anti-inflammatory regulatory …
View article: Novel UV‐B Phototherapy With a Light‐Emitting Diode Device Prevents Atherosclerosis by Augmenting Regulatory T‐Cell Responses in Mice
Novel UV‐B Phototherapy With a Light‐Emitting Diode Device Prevents Atherosclerosis by Augmenting Regulatory T‐Cell Responses in Mice Open
Background Ultraviolet B (UV‐B) irradiation is an effective treatment for human cutaneous disorders and was shown to reduce experimental atherosclerosis by attenuating immunoinflammatory responses. The aim of this study was to clarify the …
View article: Depletion of Foxp3+ regulatory T cells augments CD4+ T cell immune responses in atherosclerosis-prone hypercholesterolemic mice
Depletion of Foxp3+ regulatory T cells augments CD4+ T cell immune responses in atherosclerosis-prone hypercholesterolemic mice Open
View article: Mitochondrial DNA mutations are involved in the acquisition of cisplatin resistance in human lung cancer A549 cells
Mitochondrial DNA mutations are involved in the acquisition of cisplatin resistance in human lung cancer A549 cells Open
The efficacy of cisplatin (CDDP) has been demonstrated in the treatment of various cancers as monotherapy and combination therapy with immunotherapy. However, acquired CDDP resistance is a major obstacle to successful treatment. In the pre…
View article: CTLA-4 Protects against Angiotensin II-Induced Abdominal Aortic Aneurysm Formation in Mice
CTLA-4 Protects against Angiotensin II-Induced Abdominal Aortic Aneurysm Formation in Mice Open
Vascular inflammation via T-cell-mediated immune responses has been shown to be critically involved in the pathogenesis of abdominal aortic aneurysm (AAA). T-cell coinhibitory molecule cytotoxic T-lymphocyte–associated antigen-4 (CTLA-4) i…
View article: Inhibitory Effects of Sodium Alginate on Hepatic Steatosis in Mice Induced by a Methionine- and Choline-Deficient Diet
Inhibitory Effects of Sodium Alginate on Hepatic Steatosis in Mice Induced by a Methionine- and Choline-Deficient Diet Open
Nonalcoholic steatohepatitis (NASH) progresses from nonalcoholic fatty liver disease (NAFLD); however, efficacious drugs for NASH treatment are lacking. Sodium alginate (SA), a soluble dietary fiber extracted from brown algae, could protec…
View article: A novel in vitro co-culture model to examine contact formation between astrocytic processes and cerebral vessels
A novel in vitro co-culture model to examine contact formation between astrocytic processes and cerebral vessels Open
View article: Involvement of aquaporin‐4 in laminin‐enhanced process formation of mouse astrocytes in 2D culture: Roles of dystroglycan and α‐syntrophin in aquaporin‐4 expression
Involvement of aquaporin‐4 in laminin‐enhanced process formation of mouse astrocytes in 2D culture: Roles of dystroglycan and α‐syntrophin in aquaporin‐4 expression Open
In the central nervous system, astrocytes extend endfoot processes to ensheath synapses and microvessels. However, the mechanisms underlying this astrocytic process extension remain unclear. A limitation of the use of 2D cultured astrocyte…
View article: Mechanism of recipient cell-dependent differences in exosome uptake
Mechanism of recipient cell-dependent differences in exosome uptake Open
View article: Anti-inflammatory Effect of JBP485 on Dextran Sulfate Sodium-induced Colitis in Mice
Anti-inflammatory Effect of JBP485 on Dextran Sulfate Sodium-induced Colitis in Mice Open
JBP485 (cyclo-trans-4-L-hydroxyprolyl-L-serine), a dipeptide first isolated from Laennec that is a proprietary product made from the hydrolysate of human placenta, has been reported to have several biological properties, such as anti-hepat…
View article: Preventative Effects of Sodium Alginate on Indomethacin-induced Small-intestinal Injury in Mice
Preventative Effects of Sodium Alginate on Indomethacin-induced Small-intestinal Injury in Mice Open
Recent advances in diagnostic technologies have revealed that nonsteroidal anti-inflammatory drugs (NSAIDs) can cause serious mucosal injury in the upper and lower gastrointestinal tract (including the small intestine). A drug to treat NSA…