Schelto Kruijff
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View article: Multispectral optoacoustic tomography of salivary glands in patients with clinically suspected Sjögren’s disease: A pilot study
Multispectral optoacoustic tomography of salivary glands in patients with clinically suspected Sjögren’s disease: A pilot study Open
View article: Cut from the same cloth? investigating the personality of interventional and surgical cardiovascular specialists
Cut from the same cloth? investigating the personality of interventional and surgical cardiovascular specialists Open
Purpose Considering that the treatment of patients with complex vascular disease requires multidisciplinary collaboration in teams and personality traits can impact team dynamics, we investigated the personality structures of vascular surg…
View article: Development and Validation of a Prognostic Model for Persistent Hypoparathyroidism After Total or Completion Thyroidectomy
Development and Validation of a Prognostic Model for Persistent Hypoparathyroidism After Total or Completion Thyroidectomy Open
Background The aim of this study was to develop and validate a clinical prediction model to predict the occurrence of persistent hypoparathyroidism after total or completion thyroidectomy. Methods This multicentre retrospective cohort stud…
View article: Role of Klhl14 in senescence and epithelial-to-mesenchymal transition via TGF-[beta] modulation
Role of Klhl14 in senescence and epithelial-to-mesenchymal transition via TGF-[beta] modulation Open
KLHL14, a component of an E3-ubiquitin ligase complex, has emerged as a context-dependent oncogene or tumor suppressor, particularly important for thyroid development. Yet its role in thyroid biology remains largely unexplored. In this stu…
View article: Patient-derived medullary thyroid cancer organoids: a potential model for mechanistic studies on diagnostics and therapy
Patient-derived medullary thyroid cancer organoids: a potential model for mechanistic studies on diagnostics and therapy Open
Objective Medullary thyroid carcinoma (MTC) is a rare neuroendocrine thyroid tumor, with only 30 new patients annually in the Netherlands. PET imaging provides information on distant metastases, after which tyrosine kinase inhibitors (TKIs…
View article: A nationwide study evaluating indications and outcomes for adrenalectomy in children in the Netherlands
A nationwide study evaluating indications and outcomes for adrenalectomy in children in the Netherlands Open
Adrenalectomies in children are rare in the Netherlands, especially for non-neuroblastoma tumors, and most surgeons perform less than 1 procedure per year. Open adrenalectomy is usually performed for suspected malignant tumors, whereas min…
View article: ASO Author Reflections: Toward Better Outcomes in Poorly Differentiated Thyroid Cancer: Evaluating Adjuvant Radiotherapy, Treatment-related Morbidity, and Future Therapeutic Directions
ASO Author Reflections: Toward Better Outcomes in Poorly Differentiated Thyroid Cancer: Evaluating Adjuvant Radiotherapy, Treatment-related Morbidity, and Future Therapeutic Directions Open
View article: Comparison of quantitative laser speckle contrast and indocyanine green imaging for intestinal perfusion measurements in robot assisted surgery
Comparison of quantitative laser speckle contrast and indocyanine green imaging for intestinal perfusion measurements in robot assisted surgery Open
Adequate perfusion is essential to prevent anastomotic leakage in intestinal and rectal surgeries. This study compares Laser Speckle Contrast Imaging (LSCI) and Indocyanine Green Fluorescence Angiography (ICG-FA) for assessing blood flow i…
View article: Intra-operative laser angiography measurement of skin perfusion using indocyanine green dye in surgical treatment of laryngeal cancer: A feasibility study
Intra-operative laser angiography measurement of skin perfusion using indocyanine green dye in surgical treatment of laryngeal cancer: A feasibility study Open
Laser angiography using ICG can reliably perform skin perfusion measurements, yet it is not clinically applicable to the clinical situation studied, since no consistent patterns or reference perfusion levels can be identified.
View article: Adjuvant External Beam Radiotherapy Reduces Local Recurrence in Poorly Differentiated Thyroid Cancer
Adjuvant External Beam Radiotherapy Reduces Local Recurrence in Poorly Differentiated Thyroid Cancer Open
Background Poorly differentiated thyroid carcinoma (PDTC) accounts for 5% of all thyroid cancers and is responsible for a large proportion of thyroid cancer-related deaths. The optimal treatment approach is not clear. This study aimed to e…
View article: Quantified Fluorescence Imaging for the Perfusion of the Parathyroid Glands of Children (FLUOPATCH): A Multicenter, Proof-of-Concept Study
Quantified Fluorescence Imaging for the Perfusion of the Parathyroid Glands of Children (FLUOPATCH): A Multicenter, Proof-of-Concept Study Open
View article: Reducing surgical instrument usage: systematic review of approaches for tray optimization and its advantages on environmental impact, costs and efficiency
Reducing surgical instrument usage: systematic review of approaches for tray optimization and its advantages on environmental impact, costs and efficiency Open
Background Operating rooms generate substantial waste and budget expenditure due to extensive material usage. Reusable instruments are often packaged in trays, which accumulate instruments over time. This review quantifies the advantages o…
View article: Toxicity and Quality of Life After Locoregional Radiotherapy in Patients With Thyroid Cancer
Toxicity and Quality of Life After Locoregional Radiotherapy in Patients With Thyroid Cancer Open
Background Locoregional external beam radiotherapy (EBRT) is selectively used in thyroid cancer patients to induce locoregional control. However, despite technological advances, EBRT remains associated with toxicities. We evaluated thyroid…
View article: Intra-Operative Laser Angiography Measurement of Skin Perfusion Using Indocyanine Green Dye in Surgical Treatment of Laryngeal Cancer: A Feasibility Study
Intra-Operative Laser Angiography Measurement of Skin Perfusion Using Indocyanine Green Dye in Surgical Treatment of Laryngeal Cancer: A Feasibility Study Open
View article: Real-World Evidence of the Prevalence of Driver Mutations in Anorectal Melanoma
Real-World Evidence of the Prevalence of Driver Mutations in Anorectal Melanoma Open
View article: Does a Restrictive Diagnostic Work‐up for Thyroid Nodules Lead to a Different Papillary Thyroid Cancer Patient Population? A Comparison Between Dutch and U.S. T1‐T3 Patient Population
Does a Restrictive Diagnostic Work‐up for Thyroid Nodules Lead to a Different Papillary Thyroid Cancer Patient Population? A Comparison Between Dutch and U.S. T1‐T3 Patient Population Open
Introduction The 2015 American Thyroid Association guidelines recommend de‐escalating surgical treatment for papillary thyroid cancer (PTC). We hypothesize that the Dutch PTC population might differ due to a restrictive diagnostic policy t…
View article: Establishing reference curves for vital tissue perfusion using quantitative near-infrared fluorescence imaging with indocyanine green
Establishing reference curves for vital tissue perfusion using quantitative near-infrared fluorescence imaging with indocyanine green Open
Purpose Assessment of tissue perfusion using near-infrared fluorescence (NIR) with indocyanine green (ICG) is gaining popularity, however reliable and objective interpretation remains a challenge. Therefore, this study aimed to establish r…
View article: Trends in the Incidence, Organization of Care, and Surgical Treatment of Medullary Thyroid Cancer: A Population-Based Study
Trends in the Incidence, Organization of Care, and Surgical Treatment of Medullary Thyroid Cancer: A Population-Based Study Open
Background: Medullary thyroid cancer (MTC) is a rare cancer with variable disease course. To enable optimal care, centralization and consensus guidelines are essential. This study describes trends in the incidence, organizati…
View article: Quantified Fluorescence Imaging for the Detection and Perfusion of the Parathyroid Glands of Children (FLUOPATCH): Study Protocol for a Proof-of-Concept Study
Quantified Fluorescence Imaging for the Detection and Perfusion of the Parathyroid Glands of Children (FLUOPATCH): Study Protocol for a Proof-of-Concept Study Open
Background The most common complication of pediatric thyroid surgery is postoperative hypoparathyroidism, causing hypocalcemia and a lifelong need for daily medication, reduced quality of life and high morbidity rates. In adults, we have s…
View article: Systematic comparison of fluorescence imaging in the near-infrared and shortwave-infrared spectral range using clinical tumor samples containing cetuximab-IRDye800CW
Systematic comparison of fluorescence imaging in the near-infrared and shortwave-infrared spectral range using clinical tumor samples containing cetuximab-IRDye800CW Open
SWIR imaging using the targeted tracer cetuximab-IRDye800CW currently does not provide additional benefit over NIR imaging in ex vivo clinical samples. Background fluorescence in the SWIR region, resulting in a higher background sig…
View article: Fluorescence detection of pituitary neuroendocrine tumour during endoscopic transsphenoidal surgery using bevacizumab-800CW: a non-randomised, non-blinded, single centre feasibility and dose finding trial [DEPARTURE trial]
Fluorescence detection of pituitary neuroendocrine tumour during endoscopic transsphenoidal surgery using bevacizumab-800CW: a non-randomised, non-blinded, single centre feasibility and dose finding trial [DEPARTURE trial] Open
View article: The Definition of Recurrence of Differentiated Thyroid Cancer: A Systematic Review of the Literature
The Definition of Recurrence of Differentiated Thyroid Cancer: A Systematic Review of the Literature Open
Background: Recurrence is a key outcome to evaluate the treatment effect of differentiated thyroid carcinoma (DTC). However, no consistent definition of recurrence is available in current literature or international guideline…
View article: Expression of integrin α <sub>v</sub> β <sub>3</sub> in medullary thyroid carcinoma
Expression of integrin α <sub>v</sub> β <sub>3</sub> in medullary thyroid carcinoma Open
Aim: Tumor markers often remain elevated after intended curative resection of medullary thyroid carcinoma (MTC). The aim of this study was to determine the expression of αvβ3, a promising theranostics target, i…
View article: Real-time quantification of laser speckle contrast imaging during intestinal laparoscopic surgery: successful demonstration in a porcine intestinal ischemia model
Real-time quantification of laser speckle contrast imaging during intestinal laparoscopic surgery: successful demonstration in a porcine intestinal ischemia model Open
View article: Long‐term oncological outcomes of follicular thyroid cancer in adolescents and young adults: A nationwide population‐based study
Long‐term oncological outcomes of follicular thyroid cancer in adolescents and young adults: A nationwide population‐based study Open
Background Follicular thyroid carcinoma (FTC) in adolescents and young adults (AYAs) is rare and data on long‐term oncological outcomes are scarce. This study aimed to describe the long‐term recurrence and survival rates of AYAs with FTC, …
View article: Bevacizumab-IRDye800CW for tumor detection in fluorescence-guided meningioma surgery (LUMINA trial): a single-center phase I study
Bevacizumab-IRDye800CW for tumor detection in fluorescence-guided meningioma surgery (LUMINA trial): a single-center phase I study Open
OBJECTIVE Meningiomas are one of the most frequently occurring brain tumors and can be curatively treated with gross-total resection. A subtotal resection increases the chances of recurrence. The intraoperative identification of invisible …
View article: Why and how optical molecular imaging should further be catalyzed by nuclear medicine and molecular imaging: report from the EANM piloting group
Why and how optical molecular imaging should further be catalyzed by nuclear medicine and molecular imaging: report from the EANM piloting group Open
View article: How nuclear imaging changed parathyroid surgical strategies through time
How nuclear imaging changed parathyroid surgical strategies through time Open
View article: Empowering Tomorrow’s Cancer Specialists: Evaluating the Co-creation and Impact of Malawi’s First Surgical Oncology Summerschool
Empowering Tomorrow’s Cancer Specialists: Evaluating the Co-creation and Impact of Malawi’s First Surgical Oncology Summerschool Open
View article: Pre-Transplant Hyperparathyroidism and Graft or Patient Outcomes After Kidney Transplantation
Pre-Transplant Hyperparathyroidism and Graft or Patient Outcomes After Kidney Transplantation Open
The impact of pre-transplant parathyroid hormone (PTH) levels on early or long-term kidney function after kidney transplantation is subject of debate. We assessed whether severe hyperparathyroidism is associated with delayed graft function…