Explanipedia

Nonreportable Cell-Free DNA Prenatal Screening Test Leads to Colorectal Cancer Diagnosis in the Mother Open

Maria P. Diaz-Soto, Jessica A. Zerillo, Scott A. Shainker, Jacqueline L. Wolf · 2025

Cell-free DNA, DNA from the developing placenta, is a noninvasive prenatal screening test to detect common fetal chromosomal abnormalities. Rarely, nonreportable results occur when the test cannot accurately determine the fetus chromosomal…

Postpartum Hemorrhage: A Comprehensive Review of Medical and Surgical Treatment Open

Andrew T. Cox, Scott A. Shainker · 2025

Postpartum hemorrhage (PPH) is the leading cause of maternal morbidity and mortality worldwide. The incidence of PPH continues to rise. PPH is often responsive to both medical and surgical treatment. A stepwise multidisciplinary approach t…

Guidelines on Placenta Accreta Spectrum Disorders Open

Giulia Bonanni, María Camila López-Girón, Lisa Allen, Karin A. Fox, R.M. Silver , et al. · 2025

Importance Placenta accreta spectrum (PAS) is a complex, life-threatening condition that demands a multidisciplinary approach involving obstetrics, maternal-fetal medicine, and various surgical and medical specialties. Effective management…

Reference Range Determination for the sFlt-1/PlGF Ratio in a Diverse Cohort of Pregnant Women in the United States Open

Antonio F. Saad, David M. Haas, Eugene Chang, Scott A. Shainker, Miriah Denbo , et al. · 2025

Background The serum soluble fms-like tyrosine kinase-1 (sFlt-1) to placental growth factor (PlGF) ratio is an established tool for predicting preeclampsia in many countries but is not widely adopted in the United States. This study aimed …

Amnioreduction safety in singleton pregnancies; systematic review and meta-analysis Open

Nikan Zargarzadeh, Mohammad Haddadi, May Abiad, Ali Javinani, Eyal Krispin , et al. · 2025

Objectives Prenatal ultrasound identifies polyhydramnios in approximately 0.7 % of pregnancies. Polyhydramnios (defined as amniotic fluid index >24 cm) is associated with maternal symptoms and preterm delivery. However, amnioreduction (AR)…

Prenatal Aspiration of Fetal Ovarian Cysts: When to Intervene? A Case Report and Review of the Literature Open

Giulia Bonanni, Scott A. Shainker, Eyal Krispin, Ryne A. Didier, Terry L. Buchmiller , et al. · 2025

Fetal adnexal cysts present unique challenges during pregnancy, requiring careful management strategies to mitigate risks throughout gestation and delivery. We present the case of a 35-year-old G4P2 patient, referred to our center for a la…

Vasa previa in singleton pregnancies: diagnosis and clinical management based on an international expert consensus Open

Yinka Oyelese, Ali Javinani, Brittany Gudanowski, Eyal Krispin, Andrei Rebarber , et al. · 2024

146 A novel first-trimester ultrasound marker for cesarean scar pregnancy: the tadpole sign Open

Bridget Donovan, Laura A. Smith, Guadalupe Arambula, Anna M. Modest, Olga R. Brook , et al. · 2024

1111 The Effect of Pregnancy Complications on Quality of Life with Placenta Accreta Spectrum Open

Kripa Philip, Uma Deshmukh, Bridget Donovan, Guadalupe Arambula, Helena C. Bartels , et al. · 2024

EP16.20: Consensus protocol for diagnosis and management of singleton pregnancies with vasa previa: interim findings from a Delphi study Open

Yinka Oyelese, Ali Javinani, C. Lees, Robert M. Silver, Anthony Odibo , et al. · 2023

Objectives: The Spectrum of Placenta Accreta Disorders is an increasingly frequent iatrogenic entity whose prevalence is closely linked to Caesarean section rates.This entity is burdened with very significant maternal and fetal morbidity a…

Physiology of the Critically Ill Pregnant Patient with COVID-19 Open

Mark Dunlop, Scott A. Shainker, Margaret M. Hayes · 2023

Emergency department burden of hyperemesis gravidarum in the United States from 2006 to 2014 Open

Grace Geeganage, Johanna Iturrino, Scott A. Shainker, Sarah Ballou, Vikram Rangan , et al. · 2023

From 2006 to 2014, emergency department visits for hyperemesis gravidarum increased by 28%, with associated costs increasing by 110%, whereas the number of admissions from the emergency department for hyperemesis gravidarum decreased by 42…

Modified Delphi study of ultrasound signs associated with placenta accreta spectrum Open

Eric Jauniaux, F. D’Antonio, A. Bhide, Federico Prefumo, Robert M. Silver , et al. · 2023

Objective To determine, by expert consensus through a modified Delphi process, the role of standardized and new ultrasound signs in the prenatal evaluation of patients at high risk of placenta accreta spectrum (PAS). Methods A systematic r…

Patient Perception of Care, Outcomes, and Consequences from Placenta Accreta Spectrum: A Survey-Based Study Open

Scott A. Shainker, Ronald M. Cornely, Rebecca Astake, Michele R. Hacker · 2022

Objective Placenta accreta spectrum (PAS) is an obstetric diagnosis that carries significant risks. However, little is known about patient perceptions of care. This study was conducted to describe the patient experience, reported outcomes,…

COVID-19 in the Critically Ill Pregnant Patient Open

Matthew Levitus, Scott A. Shainker, Mai Colvin · 2022

The impact of implementing a specialized placenta accreta program on maternal morbidity Open

Bridget Donovan, Ayodele Ajayi, Jonathan L. Hecht, Liberty G. Reforma, Laura Smith , et al. · 2021

Maternity morbidity outcomes among planned versus unplanned peripartum hysterectomies Open

Liberty G. Reforma, Bridget Donovan, Laura Smith, William Choi, Jonathan L. Hecht , et al. · 2021

Risk factor profiles in in-vitro fertilization pregnancies that develop placenta accreta spectrum Open

Anna M. Modest, Brett D. Einerson, Álbaro José Nieto-Calvache, Vineet Shrivastava, Alireza A. Shamshirsaz , et al. · 2021

The new pathology classification for placenta accreta spectrum is well associated with clinical outcomes Open

Bahram Salmanian, Scott A. Shainker, Rachel D. Seaman, Anna M. Modest, Eumenia Castro , et al. · 2021

Quantitative T1 and T2 mapping by magnetic resonance fingerprinting (MRF) of the placenta before and after maternal hyperoxia Open

Jeffrey N. Stout, Congyu Liao, Borjan Gagoski, Esra Abacı Türk, Henry A. Feldman , et al. · 2021

Correction to: Rapid Cycle Implementation and Retrospective Evaluation of a SARS-CoV-2 Checklist in Labor and Delivery Open

Liana Zucco, Nadav Levy, Yunping Li, Toni Golen, Scott A. Shainker , et al. · 2021

Rapid Cycle Implementation and Retrospective Evaluation of a SARS-CoV-2 Checklist in Labor and Delivery Open

Liana Zucco, Nadav Levy, Yunping Li, Toni Golen, Scott A. Shainker , et al. · 2021

One step closer to reducing PAS morbidity Open

Scott A. Shainker · 2021

Placenta accreta spectrum (PAS), a condition of deeply adherent placental villi into the myometrium (and sometimes beyond) has seen a dramatic increase in clinical prevalence (as well as academic inquiry) in recent years. Although controve…

166 The association between pathologic severity of placenta accreta spectrum and neonatal birthweight Open

Sarah E. Detlefs, Daniela Carusi, Scott A. Shainker, Brett D. Einerson, Deirdre J. Lyell , et al. · 2021

Rapid Cycle Implementation and Retrospective Evaluation of a SARS-CoV-2 Checklist in Labor and Delivery Open

Liana Zucco, Nadav Levy, Yunping Li, Toni Golen, Scott A. Shainker , et al. · 2021

Background: Preparedness efforts for a COVID-19 outbreak required redesign and implementation of a perioperative workflow for the management of obstetric patients. In this report we describe factors which influenced rapid cycle implementat…

Rapid Cycle Implementation and Retrospective Evaluation of a SARS-CoV-2 Checklist in Labor and Delivery (vol 21, 755, 2021) Open

Liana Zucco, Nadav Levy, Y. P. Li, Toni Golen, Scott A. Shainker , et al. · 2021

Adaptation of an Obstetric Anesthesia Service for the Severe Acute Respiratory Syndrome Coronavirus-2 Pandemic: Description of Checklists, Workflows, and Development Tools Open

Yunping Li, Erin J. Ciampa, Liana Zucco, Nadav Levy, Meredith Colella , et al. · 2020

Background: Care of the pregnant patient during the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic presents many challenges, including creating parallel workflows for infected and noninfected patients, minimizing was…

Keeping Pregnant Patients Safe During COVID-19 Pandemic Open

Philip E. Hess, Blair J. Wylie, Toni Golen, Scott A. Shainker, Chloe Zera , et al. · 2020

During a crisis such as the coronavirus disease 2019 (COVID-19) pandemic, a hospital can suspend all elective surgery to expand capacity for intensive care;1 however, the clinical care on the Labor and Delivery Unit (L&D) cannot be delayed…

Rapid Cycle Implementation and Retrospective Evaluation of a SARS-CoV-2 Checklist in Labor and Delivery Open

Liana Zucco, Nadav Levy, Yunping Li, Toni Golen, Scott A. Shainker , et al. · 2020

Background : Preparedness efforts for a COVID-19 outbreak required redesign and implementation of a perioperative workflow for the management of obstetric patients. In this report we describe the rapid cycle implementation of a comprehensi…

A multidisciplinary telemedicine model for management of coronavirus disease 2019 (COVID-19) in obstetrical patients Open

Liberty G. Reforma, Cassandra R. Duffy, Ai‐ris Y. Collier, Blair J. Wylie, Scott A. Shainker , et al. · 2020

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