Scott A. Tomlins
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Author Swipe
View article: Figure S6 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models
Figure S6 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models Open
Gene level correlation of copy number by MiMouse and MGA
View article: Figure S10 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models
Figure S10 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models Open
Aneuploidy events in human HGSC and CRC
View article: Table S2 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models
Table S2 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models Open
Engineered mutation detection by MiMouse in colorectal cancer (CRC) samples
View article: Figure 2 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models
Figure 2 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models Open
Aneuploidy and admixture detection considerations for mouse CGP by MiMouse. A, To simulate the effects of reduced coverage by CGP vs. near genome-wide technologies, we developed a metric, Rc, in which c
View article: Figure S12 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models
Figure S12 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models Open
Focused NGS panels overestimate FGA vs. CGP and WES in human HGSC
View article: Figure S5 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models
Figure S5 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models Open
Aneuploidy detection performance of MiMouse with and without the directionality filter and by variable Rc thresholds and c
View article: Figure S7 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models
Figure S7 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models Open
Indels limit informative SNPs from Ion Torrent based MiMouse profiling
View article: Figure S14 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models
Figure S14 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models Open
CRC tumors from AK and AKP mice show somatic loss of the second Apc allele
View article: Table S5 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models
Table S5 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models Open
Clinically relevant mutations and copy number alterations for HGSC and CRC cohorts
View article: Figure S2 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models
Figure S2 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models Open
Aneuploidy detection considerations for reduced coverage approaches like MiMouse
View article: Figure S4 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models
Figure S4 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models Open
Coverage characteristics of the MiMouse panel
View article: Figure S3 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models
Figure S3 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models Open
Aneuploidy detection performance across TCGA tumor types using different Rc thresholds by breadth of chromosome arm coverage ( c )
View article: Table S4 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models
Table S4 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models Open
Somatic mutations identified in MiMouse profiled colorectal cancer (CRC) and fallopian tube (ovarian) high grade serous cancer (HGSC) and endometrioid carcinoma (EC) tumor samples
View article: Table S7 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models
Table S7 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models Open
Human prioriztized amino acid positions (oncokb) and mouse analog
View article: Table S1 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models
Table S1 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models Open
MiMouse panel composition & summary table of markers
View article: Figure S8 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models
Figure S8 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models Open
Highly correlated detection of focal, sub‐gene deep (homozygous) deletions by MiMouse
View article: Figure S11 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models
Figure S11 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models Open
FGA differs in human and mouse models of HGSC and CRC
View article: Figure S13 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models
Figure S13 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models Open
Comparison of aneuploidy between our HGSC models and other models
View article: Figure S1 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models
Figure S1 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models Open
Approach for evaluating the functional significance of mutations detected by mouse CGP
View article: Figure 1 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models
Figure 1 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models Open
Overview of the development and application of MiMouse for mouse CGP and genomic credentialing. Human (peach)- and mouse (lavender)-specific resources were considered through simulations to develop MiMouse, a 135-gene (0.5 Mb) CGP assay de…
View article: Figure 4 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models
Figure 4 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models Open
MiMouse for CGP and genomic credentialing across the neoplastic spectrum of two large cohorts of inducible fallopian tube (ovary) and colorectal (colorectal carcinoma) tumors. A, Promoters and transgenes used in the cohorts. Ovary a…
View article: Figure 5 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models
Figure 5 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models Open
Genomic credentialing of increased FGA in fallopian tube HGSC and mouse genome arrangement–specific mechanisms of Smad4 loss in colorectal carcinoma by MiMouse. A, Comparison of gene-level FGA was performed between human (TCG…
View article: Figure S17 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models
Figure S17 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models Open
Comparison of dependency scores and RNA expression for syntenic region 13q12.2
View article: Figure 6 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models
Figure 6 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models Open
A, Cross-species analysis incorporating synteny prioritizes regions for driver gene localization in colorectal carcinoma. To identify colorectal carcinoma specific, we compared arm-level gains (aneuploidy) in human TCGA colorectal c…
View article: Figure S15 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models
Figure S15 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models Open
Aneuploidy comparison between HGSC and CRC models
View article: Figure S9 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models
Figure S9 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models Open
MiMouse for CGP and genomic credentialling across the neoplastic spectrum of two large cohorts of inducible fallopian tube (Ovary) and colorectal (CRC) tumors
View article: Table S6 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models
Table S6 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models Open
Gene level copy number calls (log2 copy number ratio [CNR]) by MiMouse for colorectal cancer (CRC) and high grade serous cancer (HGSC) tumor samples
View article: Figure 3 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models
Figure 3 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models Open
Validation of aneuploidy and admixture detection for mouse CGP by MiMouse. A, For validation of aneuploidy detection by MiMouse, 48 HGSC FFPE tumor samples were tested by MiMouse and Infinium MGA. PPA and negative percent agreement …
View article: Figure S16 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models
Figure S16 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models Open
Contribution of aneuploidy vs. focal events to FGA in human and mouse CRC and HGSC
View article: Table S3 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models
Table S3 from Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models Open
Table of sequencing statistics, sample information, and strain information for colorectal (CRC) and high grade serous cancer (HGSC) samples