Shai Friedland
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View article: NR0B1 alters the 9-<i>cis</i>-retinoic acid response in Ewing Sarcoma cells
NR0B1 alters the 9-<i>cis</i>-retinoic acid response in Ewing Sarcoma cells Open
Pediatric cancers are often characterized by relatively low DNA mutation rates and are frequently driven instead by alterations in gene expression programs. In Ewing Sarcoma (EwS), these changes result from the activity of an oncogenic fus…
View article: Lumen-apposing stents versus plastic stents in the management of pancreatic pseudocysts: a large, comparative, international, multicenter study
Lumen-apposing stents versus plastic stents in the management of pancreatic pseudocysts: a large, comparative, international, multicenter study Open
BACKGROUND: Larger caliber lumen-apposing stents (LAMSs) have been increasingly used in the management of pancreatic fluid collections, specifically when solid debris is present; however, their advantages over smaller caliber plastic stent…
View article: Correction: Lumen-apposing stents versus plastic stents in the management of pancreatic pseudocysts: a large, comparative, international, multicenter study
Correction: Lumen-apposing stents versus plastic stents in the management of pancreatic pseudocysts: a large, comparative, international, multicenter study Open
Correction to: Lumen-apposing stents versus plastic stents in the management of pancreatic pseudocysts: a large, comparative, international, multicenter study
View article: Evaluation of computer aided detection during colonoscopy among Veterans: Randomized clinical trial
Evaluation of computer aided detection during colonoscopy among Veterans: Randomized clinical trial Open
BACKGROUND There has been significant interest in use of computer aided detection (CADe) devices in colonoscopy to improve polyp detection and reduce miss rate. AIM To investigate the use of CADe amongst veterans. METHODS Between September…
View article: Strategies to manage the difficult colonoscopy
Strategies to manage the difficult colonoscopy Open
During endoscopy, an endoscopist is inevitably faced with the occasional “difficult colonoscopy,” in which the endoscopist finds it challenging to advance the endoscope to the cecum. Beyond optimization of technique, with minimized looping…
View article: De Novo Diagnosis of Lymphocytic Colitis After SARS-CoV-2 Vaccination
De Novo Diagnosis of Lymphocytic Colitis After SARS-CoV-2 Vaccination Open
SARS-CoV-2 mRNA vaccines are safe and effective for most patients. Gastrointestinal complications reported after vaccination have included gastroparesis and inflammatory bowel disease flares. In this study, we present a unique case of lymp…
View article: Endoscopic submucosal dissection for colorectal dysplasia in inflammatory bowel disease: a US multicenter study
Endoscopic submucosal dissection for colorectal dysplasia in inflammatory bowel disease: a US multicenter study Open
Background and study aims In patients with inflammatory bowel disease (IBD), endoscopically visible lesions with distinct borders can be considered for endoscopic resection. The role of endoscopic submucosal dissection (ESD) for these lesi…
View article: Development and Clinical Validation of a Blood Test for Early Detection of Colorectal Adenomas and Cancer for Screening and Postpolypectomy Surveillance
Development and Clinical Validation of a Blood Test for Early Detection of Colorectal Adenomas and Cancer for Screening and Postpolypectomy Surveillance Open
A multimodal blood test that included CECs and somatic mutations with adjustment for age and sex demonstrated high sensitivity for the diagnosis of advanced colorectal neoplasia. The resulting score captures prognostic information for CRC …
View article: Over-the-Scope Clip in the Treatment of Gastrointestinal Leaks and Perforations
Over-the-Scope Clip in the Treatment of Gastrointestinal Leaks and Perforations Open
While perforations, postoperative fistulas, and leaks have traditionally led to surgical or interventional radiology consultation for management, the introduction of the over-the-scope clip has allowed increased therapeutic possibilities f…
View article: Is Submucosal Injection Helpful in Cold Snare Polypectomy for Small Colorectal Polyps?
Is Submucosal Injection Helpful in Cold Snare Polypectomy for Small Colorectal Polyps? Open
The effect of submucosal injection in CSP was not significant for small colorectal polyps.
View article: Predictive factors for adenoma detection rates: a video study of endoscopist practices
Predictive factors for adenoma detection rates: a video study of endoscopist practices Open
Background and study aims In 2015, the American Society for Gastrointestinal Endoscopy (ASGE) and American College of Gastroenterology (ACG) Task Force on Quality in Endoscopy deemed adenoma detection rate (ADR) the most important quality …
View article: Ideal Method for Small Bowel Preparation before Video Capsule Endoscopy
Ideal Method for Small Bowel Preparation before Video Capsule Endoscopy Open
See the article "The Efficacy of 4 Liters of Clear Liquids for Small Bowel Preparation Prior to Video Capsule Endoscopy" in Volume 53 on page 713.
View article: Risk of ambulatory colonoscopy in patients with cirrhosis: a propensity-score matched cohort study
Risk of ambulatory colonoscopy in patients with cirrhosis: a propensity-score matched cohort study Open
Background and study aims Patients with cirrhosis demonstrate alterations in physiology, hemodynamics, and immunity which may increase procedural risk. There exist sparse data regarding the safety of performing ambulatory colonoscopy in pa…
View article: Endoscopic submucosal dissection (ESD) for Barrett’s esophagus (BE)-related early neoplasia after standard endoscopic management is feasible and safe
Endoscopic submucosal dissection (ESD) for Barrett’s esophagus (BE)-related early neoplasia after standard endoscopic management is feasible and safe Open
Background and study aims There is little data on the feasibility and safety of endoscopic submucosal dissection (ESD) as a salvage treatment for Barrett’s esophagus (BE)-related neoplasia after standard endoscopic treatments. Patients and…
View article: Endoscopic Diagnosis of Nonpedunculated Dysplasia during Surveillance of Ulcerative Colitis: A Survey-Based Multinational Study
Endoscopic Diagnosis of Nonpedunculated Dysplasia during Surveillance of Ulcerative Colitis: A Survey-Based Multinational Study Open
Diagnostic performance based on the endoscopist's intention to perform a biopsy for nonpedunculated potentially dysplastic lesions in UC patients was suboptimal according to this survey-based study.
View article: Novel Circulating Tumor Cell Assay for Detection of Colorectal Adenomas and Cancer
Novel Circulating Tumor Cell Assay for Detection of Colorectal Adenomas and Cancer Open
OBJECTIVES: There is a significant unmet need for a blood test with adequate sensitivity to detect colorectal cancer (CRC) and adenomas. We describe a novel circulating tumor cell (CTC) platform to capture colorectal epithelial cells assoc…
View article: Endoscopic submucosal dissection in the West
Endoscopic submucosal dissection in the West Open
Endoscopic resection has emerged as the first line therapy for pre-malignant conditions throughout the gastrointestinal (GI) tract. Resection techniques have evolved from forceps avulsion and snare polypectomy to endoscopic mucosal resecti…
View article: Lumen apposing metal stents are superior to plastic stents in pancreatic walled-off necrosis: a large international multicenter study
Lumen apposing metal stents are superior to plastic stents in pancreatic walled-off necrosis: a large international multicenter study Open
Background and study aims The use of lumen apposing metal stents (LAMS) during EUS-guided transmural drainage (EUS-TD) of pancreatic walled-off necrosis (WON) has gained popularity. Data supporting their use in WON over plastic stents (PS)…
View article: Precision care for Barrett’s esophagus
Precision care for Barrett’s esophagus Open
Modern recognition and management of Barrett's esophagus, a precursor to esophageal adenocarcinoma depends on diagnostic accuracy, risk assessment, technical expertise and consideration of many options to best tailor therapy for every pati…