Scott Penfold
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View article: Radiological assessment of Cerrobend and tungsten carbide as aperture materials in proton therapy
Radiological assessment of Cerrobend and tungsten carbide as aperture materials in proton therapy Open
Brass remains the optimal aperture material, but tungsten carbide and Cerrobend could be viable alternatives for PBS proton therapy. Nickel's high residual activity could pose challenges for DCS.
View article: Australian Particle Therapy Clinical Quality Registry (ASPIRE) protocol (TROG 21.12): a multicentre prospective study on patients with rare tumours, treated with radiation therapy
Australian Particle Therapy Clinical Quality Registry (ASPIRE) protocol (TROG 21.12): a multicentre prospective study on patients with rare tumours, treated with radiation therapy Open
Introduction In 2020, the Australian Medical Services Advisory Committee (MSAC) recommended new proton beam therapy (PBT) item numbers be added to the Medicare Benefits Schedule. During the MSAC 1638 application process, MSAC recognised th…
View article: Single high‐energy arc proton therapy with Bragg peak boost (SHARP)
Single high‐energy arc proton therapy with Bragg peak boost (SHARP) Open
Introduction Because of the co‐location of critical organs at risk, base of skull tumours require steep dose gradients to achieve the prescribed dosimetric criteria. When available, proton beam therapy (PBT) is often considered a desirable…
View article: Dosimetric comparison of gantry and horizontal fixed‐beam proton therapy treatment plans for base of skull chordoma
Dosimetric comparison of gantry and horizontal fixed‐beam proton therapy treatment plans for base of skull chordoma Open
Introduction Australia's first proton beam therapy (PBT) centre will house a fixed‐beam room and two gantry rooms. As the only PBT facility in Australia for at least the short term, there is a need to efficiently allocate treatment appoint…
View article: PP75 Using Real World Evidence To Support The Reimbursement Of Proton Therapy Across A Broad Range Of Rare Cancers
PP75 Using Real World Evidence To Support The Reimbursement Of Proton Therapy Across A Broad Range Of Rare Cancers Open
Introduction The Australian Bragg Centre for Proton Therapy and Research in Adelaide will be Australia’s first center with the capacity to deliver proton beam therapy (PBT). PBT uses energy from protons to target cancer cells while minimiz…
View article: Dosimetric Comparison of Proton Therapy and CyberKnife in Stereotactic Body Radiation Therapy for Liver Cancers
Dosimetric Comparison of Proton Therapy and CyberKnife in Stereotactic Body Radiation Therapy for Liver Cancers Open
Background : Stereotactic body radiation therapy (SBRT) has been increasingly used for the ablation of liver tumours. CyberKnife and proton beam therapy (PBT) are two advanced treatment technologies suitable to deliver SBRT with high dose …
View article: Issue Information
Issue Information Open
Image-guided thermal ablation for patients
View article: Proton‐to‐photon comparative treatment planning guidelines for the Australian context
Proton‐to‐photon comparative treatment planning guidelines for the Australian context Open
Proton‐to‐photon comparative treatment planning is a current requirement of Australian Government funding for patients to receive proton beam therapy (PBT) overseas, and a future requirement for Medicare funding of PBT in Australia. Becaus…
View article: Volumetric modulated arc therapy (<scp>VMAT</scp>) comparison to <scp>3D</scp>‐conformal technique in lung stereotactic ablative radiotherapy (<scp>SABR</scp>)
Volumetric modulated arc therapy (<span>VMAT</span>) comparison to <span>3D</span>‐conformal technique in lung stereotactic ablative radiotherapy (<span>SABR</span>) Open
Introduction Stereotactic ablative radiotherapy (SABR) can be a curative option for non‐small cell lung cancer (NSCLC) and oligometastatic lung disease. Volumetric modulated arc therapy (VMAT) has offered further advancements in terms of r…
View article: Radiation shielding assessment of high‐energy proton imaging at a proton therapy facility
Radiation shielding assessment of high‐energy proton imaging at a proton therapy facility Open
Background Proton imaging makes use of high‐energy, low‐intensity proton beams that fully traverse the patient and has been suggested to reduce range uncertainty in proton therapy. Upright patient positioning with proton imaging is being c…
View article: The Role of Hypofractionation in Proton Therapy
The Role of Hypofractionation in Proton Therapy Open
Hypofractionated radiotherapy is an attractive approach for minimizing patient burden and treatment cost. Technological advancements in external beam radiotherapy (EBRT) delivery and image guidance have resulted in improved targeting and c…
View article: A Novel TPS Toolkit to Assess Correlation Between Transit Fluence Dosimetry and DVH Metrics for Adaptive Head and Neck Radiotherapy
A Novel TPS Toolkit to Assess Correlation Between Transit Fluence Dosimetry and DVH Metrics for Adaptive Head and Neck Radiotherapy Open
Inter-fractional anatomical variations in head and neck (H&N;) cancer patients can lead to clinically significant dosimetric changes. Adaptive re-planning should thus commence to negate any potential over-dosage to organs-at-risk (OAR), as…
View article: Impact of Breast Size on Dosimetric Indices in Proton Versus X-ray Radiotherapy for Breast Cancer
Impact of Breast Size on Dosimetric Indices in Proton Versus X-ray Radiotherapy for Breast Cancer Open
Deep inspiration breath hold (DIBH) radiotherapy is a technique used to manage early stage left-sided breast cancer. This study compared dosimetric indices of patient-specific X-ray versus proton therapy DIBH plans to explore differences i…
View article: Estimating the second primary cancer risk due to proton therapy compared to hybrid IMRT for left sided breast cancer
Estimating the second primary cancer risk due to proton therapy compared to hybrid IMRT for left sided breast cancer Open
The use of proton therapy for breast treatments leads to reduced risk estimates for secondary carcinogenesis. Therefore, proton therapy shows promise in improving the long term treatment outcome of breast patients.
View article: Individualised selection of left‐sided breast cancer patients for proton therapy based on cost‐effectiveness
Individualised selection of left‐sided breast cancer patients for proton therapy based on cost‐effectiveness Open
Introduction The significantly greater cost of proton therapy compared with X‐ray therapy is frequently justified by the expected reduction in normal tissue toxicity. This is often true for indications such as paediatric and skull base can…
View article: An inhomogeneous most likely path formalism for proton computed tomography
An inhomogeneous most likely path formalism for proton computed tomography Open
We have presented an MLP formalism that accounts for material composition. In most clinical cases a water scattering environment can be assumed, however in certain cases of significant heterogeneity the proposed algorithm may improve proto…
View article: Sunday 31 March, 2019
Sunday 31 March, 2019 Open
From professional to patient
View article: Dosimetric comparison of stopping power calibration with dual‐energy CT and single‐energy CT in proton therapy treatment planning
Dosimetric comparison of stopping power calibration with dual‐energy CT and single‐energy CT in proton therapy treatment planning Open
Purpose: The accuracy of proton dose calculation is dependent on the ability to correctly characterize patient tissues with medical imaging. The most common method is to correlate computed tomography (CT) numbers obtained via single‐energy…