Sean Lybrand
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View article: Medication persistence trajectories among individuals prescribed lipid‐lowering therapy in primary care settings: A retrospective cohort study
Medication persistence trajectories among individuals prescribed lipid‐lowering therapy in primary care settings: A retrospective cohort study Open
Aims This study aimed to identify distinct trajectories of lipid‐modifying medication (LMM) persistence over time and to explore characteristics associated with each pattern. Methods Using primary care data from IQVIA, we conducted a retro…
View article: Discontinuation of lipid-modifying agents and failure to achieve target LDL cholesterol levels across cardiovascular risk groups
Discontinuation of lipid-modifying agents and failure to achieve target LDL cholesterol levels across cardiovascular risk groups Open
Long-term adherence to LMAs remains a challenge, particularly in low-risk. Target achievement was poor, highlighting gaps in therapeutic optimization, patient engagement, and monitoring.
View article: Bring Out Your Dead: A Review of the Cost Minimisation Approach in Health Technology Assessment Submissions to the Australian Pharmaceutical Benefits Advisory Committee
Bring Out Your Dead: A Review of the Cost Minimisation Approach in Health Technology Assessment Submissions to the Australian Pharmaceutical Benefits Advisory Committee Open
View article: Expanding access to fracture liaison services in Australia for people with minimal trauma fractures: a system dynamics modelling study
Expanding access to fracture liaison services in Australia for people with minimal trauma fractures: a system dynamics modelling study Open
Objectives To project how many minimal trauma fractures could be averted in Australia by expanding the number and changing the operational characteristics of fracture liaison services (FLS). Study design System dynamics modelling. Setting,…
View article: Calling for Urgent Actions to Improve Lipid Management in Australia–Low Medication Adherence and Poor Therapeutic Goal Attainment Lead to Poor Outcomes and Wasted Resources
Calling for Urgent Actions to Improve Lipid Management in Australia–Low Medication Adherence and Poor Therapeutic Goal Attainment Lead to Poor Outcomes and Wasted Resources Open
View article: Table of Contents
Table of Contents Open
View article: Lost Therapeutic Benefit of Delayed Low-Density Lipoprotein Cholesterol Control in Statin-Treated Patients and Cost-Effectiveness Analysis of Lipid-Lowering Intensification
Lost Therapeutic Benefit of Delayed Low-Density Lipoprotein Cholesterol Control in Statin-Treated Patients and Cost-Effectiveness Analysis of Lipid-Lowering Intensification Open
View article: EE217 Lost Therapeutic Benefit of Delayed LDL-C Control and Cost-Effectiveness Analysis of Lipid-Lowering Intensification
EE217 Lost Therapeutic Benefit of Delayed LDL-C Control and Cost-Effectiveness Analysis of Lipid-Lowering Intensification Open
View article: Gazing through time and beyond the health sector: Insights from a system dynamics model of cardiovascular disease in Australia
Gazing through time and beyond the health sector: Insights from a system dynamics model of cardiovascular disease in Australia Open
Objective To construct a whole-of-system model to inform strategies that reduce the burden of cardiovascular disease (CVD) in Australia. Methods A system dynamics model was developed with a multidisciplinary modelling consortium. The model…
View article: Sharing administrative health data with private industry: A report on two citizens' juries
Sharing administrative health data with private industry: A report on two citizens' juries Open
Background There is good evidence of both community support for sharing public sector administrative health data in the public interest and concern about data security, misuse and loss of control over health information, particularly if pr…
View article: Alignment of preferences in the treatment of multiple myeloma – a discrete choice experiment of patient, carer, physician, and nurse preferences
Alignment of preferences in the treatment of multiple myeloma – a discrete choice experiment of patient, carer, physician, and nurse preferences Open
View article: Analysis of PBAC submissions and outcomes for medicines (2010–2018)
Analysis of PBAC submissions and outcomes for medicines (2010–2018) Open
Objectives The Pharmaceutical Benefits Scheme (PBS) provides timely, reliable, and affordable access to necessary medicines for Australians. We reviewed the Pharmaceutical Benefits Advisory Committee (PBAC) submissions and their related ou…
View article: Table of Contents and Advertisements
Table of Contents and Advertisements Open
View article: Analysis of sponsor hearings on health technology assessment decision making
Analysis of sponsor hearings on health technology assessment decision making Open
Objective The aim of this study was to get a better understanding of the frequency of Pharmaceutical Benefits Advisory Committee (PBAC) hearings, the factors that influence a sponsor’s decision to proceed with a hearing and to assess the i…