Sean M. Kearney
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View article: Influence of heterotrophs on phage infection of marine picocyanobacteria
Influence of heterotrophs on phage infection of marine picocyanobacteria Open
Picocyanobacteria Prochlorococcus and Synechococcus coexist with both their lytic phages and heterotrophic bacteria in the oceans. These lytic phages are a significant cause of mortality, and heterotrophic bacteria have been shown to incre…
View article: Ultra-Low-Field Portable MRI and Extracorporeal Membrane Oxygenation: Preclinical Safety Testing
Ultra-Low-Field Portable MRI and Extracorporeal Membrane Oxygenation: Preclinical Safety Testing Open
CONTEXT: Conventional MRI is incompatible with extracorporeal membrane oxygenation (ECMO) cannulas and pumps. Ultra-low-field portable MRI (ULF-pMRI) with 0.064 Tesla may provide a solution, but its safety and compatibility is unknown. HYP…
View article: Chitin degradation by<i>Synechococcus</i>WH7803
Chitin degradation by<i>Synechococcus</i>WH7803 Open
Chitin is an abundant, carbon-rich polymer in the marine environment. Chitinase activity has been detected in spent media of Synechococcus WH7803 cultures – yet it was unclear which specific enzymes were involved. Here we delivered a CRISP…
View article: Supplemental Figure 3 from Dietary Microbes Modulate Transgenerational Cancer Risk
Supplemental Figure 3 from Dietary Microbes Modulate Transgenerational Cancer Risk Open
L. reuteri dietary enrichment protects the F1 progeny of NWD-fed mothers from transgenerational cancer. Pulmonary adenocarcinoma, hepatocellular carcinoma and mesenteric lymph node lymphoma in the children of mothers consuming NWD are show…
View article: Supplemental Figure 3 from Dietary Microbes Modulate Transgenerational Cancer Risk
Supplemental Figure 3 from Dietary Microbes Modulate Transgenerational Cancer Risk Open
L. reuteri dietary enrichment protects the F1 progeny of NWD-fed mothers from transgenerational cancer. Pulmonary adenocarcinoma, hepatocellular carcinoma and mesenteric lymph node lymphoma in the children of mothers consuming NWD are show…
View article: Author Correction: Microbial community dynamics and coexistence in a sulfide-driven phototrophic bloom
Author Correction: Microbial community dynamics and coexistence in a sulfide-driven phototrophic bloom Open
ISSN:2524-6372
View article: Supplemental Figure 1 from Dietary Microbes Modulate Transgenerational Cancer Risk
Supplemental Figure 1 from Dietary Microbes Modulate Transgenerational Cancer Risk Open
(A) Selected immunohistochemical features of transgenerational neoplasms including TTF1 immunoreactivity of pulmonary carcinoma, Von Willebrand factor expression of hepatic hemagiosarcoma and high numbers of proliferating ki-67-positive ce…
View article: Supplemental Table 1 from Dietary Microbes Modulate Transgenerational Cancer Risk
Supplemental Table 1 from Dietary Microbes Modulate Transgenerational Cancer Risk Open
Nutritional profile of special diets fed to mice.
View article: Supplemental Figure 2 from Dietary Microbes Modulate Transgenerational Cancer Risk
Supplemental Figure 2 from Dietary Microbes Modulate Transgenerational Cancer Risk Open
Control and NWD-treated mice cluster separately by microbiota. NWD-treated mice carry fewer Bacteroidetes in general than their control diet-fed counterparts. Overall, there is a shift towards higher abundance of OTUs from the Firmicutes p…
View article: Supplemental Table 1 from Dietary Microbes Modulate Transgenerational Cancer Risk
Supplemental Table 1 from Dietary Microbes Modulate Transgenerational Cancer Risk Open
Nutritional profile of special diets fed to mice.
View article: Supplemental Figure 2 from Dietary Microbes Modulate Transgenerational Cancer Risk
Supplemental Figure 2 from Dietary Microbes Modulate Transgenerational Cancer Risk Open
Control and NWD-treated mice cluster separately by microbiota. NWD-treated mice carry fewer Bacteroidetes in general than their control diet-fed counterparts. Overall, there is a shift towards higher abundance of OTUs from the Firmicutes p…
View article: Data from Dietary Microbes Modulate Transgenerational Cancer Risk
Data from Dietary Microbes Modulate Transgenerational Cancer Risk Open
Environmental factors are suspected in the increase of obesity and cancer in industrialized countries but are poorly understood. Here, we used animal models to test how future generations may be affected by Westernized diets. We discover l…
View article: Data from Dietary Microbes Modulate Transgenerational Cancer Risk
Data from Dietary Microbes Modulate Transgenerational Cancer Risk Open
Environmental factors are suspected in the increase of obesity and cancer in industrialized countries but are poorly understood. Here, we used animal models to test how future generations may be affected by Westernized diets. We discover l…
View article: Supplemental Figure 1 from Dietary Microbes Modulate Transgenerational Cancer Risk
Supplemental Figure 1 from Dietary Microbes Modulate Transgenerational Cancer Risk Open
(A) Selected immunohistochemical features of transgenerational neoplasms including TTF1 immunoreactivity of pulmonary carcinoma, Von Willebrand factor expression of hepatic hemagiosarcoma and high numbers of proliferating ki-67-positive ce…
View article: ATP—Sensitive Potassium Channel Opener Diazoxide Reduces Myocardial Stunning in a Porcine Regional With Subsequent Global Ischemia Model
ATP—Sensitive Potassium Channel Opener Diazoxide Reduces Myocardial Stunning in a Porcine Regional With Subsequent Global Ischemia Model Open
Background ATP‐sensitive potassium channels are inhibited by ATP and open during metabolic stress, providing endogenous myocardial protection. Pharmacologic opening of ATP potassium channels with diazoxide preserves myocardial function fol…
View article: Identification of commensals and molecular components mediating trypsin degradation in the large intestine
Identification of commensals and molecular components mediating trypsin degradation in the large intestine Open
The gastrointestinal tract is constitutively exposed to proteases including trypsin, a serine protease originating from the pancreas1. Elevated trypsin levels in the large intestine have been implicated in pathological conditions including…
View article: Filter Plating Method for Rendering Picocyanobacteria Cultures Free of Heterotrophic Bacterial Contaminants and Clonal
Filter Plating Method for Rendering Picocyanobacteria Cultures Free of Heterotrophic Bacterial Contaminants and Clonal Open
Isolates of the marine picocyanobacteria, Prochlorococcus and Synechococcus , are often accompanied by diverse heterotrophic “contaminating” bacteria, which can act as confounding variables in otherwise controlled experiments. Traditional …
View article: Dynamic Colonization of Microbes and Their Functions after Fecal Microbiota Transplantation for Inflammatory Bowel Disease
Dynamic Colonization of Microbes and Their Functions after Fecal Microbiota Transplantation for Inflammatory Bowel Disease Open
Fecal microbiota transplantation (FMT)—transferring fecal microbes from a healthy donor to a sick patient—has shown promise for gut diseases such as inflammatory bowel disease. However, unlike pharmaceuticals, fecal transplants are complex…
View article: Additional file 1 of Microbial diversity of co-occurring heterotrophs in cultures of marine picocyanobacteria
Additional file 1 of Microbial diversity of co-occurring heterotrophs in cultures of marine picocyanobacteria Open
Additional file 1: Table S1. Metadata associated with the isolation of each cyanobacterial culture. Table S2. Indicator Species associated with either Prochlorococcus or Synechococcus cultures. Table S3. OTUs shared between this study, Beh…
View article: Identification of unique bile acid-metabolizing bacteria from the microbiome of centenarians
Identification of unique bile acid-metabolizing bacteria from the microbiome of centenarians Open
Centenarians, or individuals who have lived more than a century, represent the ultimate model of successful longevity associated with decreased susceptibility to ageing-associated illness and chronic inflammation. The gut microbiota is con…
View article: Microbial Diversity of Co-occurring Heterotrophs in Cultures of Marine Picocyanobacteria
Microbial Diversity of Co-occurring Heterotrophs in Cultures of Marine Picocyanobacteria Open
Background Prochlorococcus and Synechococcus are responsible for around 10% of global net primary productivity, serving as part of the foundation of marine food webs. Heterotrophic bacteria are often co-isolated with these picocyanobacteri…
View article: Microbial Diversity of Co-occurring Heterotrophs in Cultures of Marine Picocyanobacteria
Microbial Diversity of Co-occurring Heterotrophs in Cultures of Marine Picocyanobacteria Open
BackgroundProchlorococcus and Synechococcus are responsible for around 10% of global net primary productivity, serving as part of the foundation of marine food webs. Heterotrophic bacteria are often co-isolated with these picocyanobacteria…
View article: Microbial Diversity of Co-occurring Heterotrophs in Cultures of Marine Picocyanobacteria
Microbial Diversity of Co-occurring Heterotrophs in Cultures of Marine Picocyanobacteria Open
Prochlorococcus and Synechococcus are responsible for around 10% of global net primary productivity, serving as part of the foundation of marine food webs. Heterotrophic bacteria are often co-isolated with these picocyanobacteria in seawat…
View article: Association of lanthipeptide genes with TnpA<sub>REP</sub>transposases in marine picocyanobacteria
Association of lanthipeptide genes with TnpA<sub>REP</sub>transposases in marine picocyanobacteria Open
Lanthipeptides are a family of ribosomally synthesized, post-translationally modified peptides that are widespread among bacteria, typically functioning as antibacterials. The marine picocyanobacteria Prochlorococcus and Synechococcus prod…