Christian Scheer
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View article: Regional sepsis care in Catalonia: comparative insights from a secondary analysis of the European Sepsis Care Survey
Regional sepsis care in Catalonia: comparative insights from a secondary analysis of the European Sepsis Care Survey Open
View article: Infrastructure and current practice of blood culture diagnostics in patients with sepsis: teachings and recommendations from the European Sepsis Care Survey
Infrastructure and current practice of blood culture diagnostics in patients with sepsis: teachings and recommendations from the European Sepsis Care Survey Open
View article: Computer-Interpretable Quality Indicators for Intensive Care Medicine: Development and Validation Study
Computer-Interpretable Quality Indicators for Intensive Care Medicine: Development and Validation Study Open
Background Quality indicators (QIs) can help assess intensive care quality, identify potential for improvement, and ultimately enhance patient outcomes. Therefore, the German Interdisciplinary Association of Critical Care and Emergency Med…
View article: Status of Sepsis Care in European Hospitals: Results from an International Cross-Sectional Survey
Status of Sepsis Care in European Hospitals: Results from an International Cross-Sectional Survey Open
Rationale: Early detection, standardized therapy, adequate infrastructure, and strategies for quality improvement should constitute essential components of every hospital's sepsis plan. Objectives: To investigate the extent t…
View article: Blood Culture Practices and Microbiological Capacity for Sepsis Diagnostics in Europe: Analysis of the European Sepsis Care Survey
Blood Culture Practices and Microbiological Capacity for Sepsis Diagnostics in Europe: Analysis of the European Sepsis Care Survey Open
View article: Comparison of post-COVID-19 symptoms in patients infected with the SARS-CoV-2 variants delta and omicron—results of the Cross-Sectoral Platform of the German National Pandemic Cohort Network (NAPKON-SUEP)
Comparison of post-COVID-19 symptoms in patients infected with the SARS-CoV-2 variants delta and omicron—results of the Cross-Sectoral Platform of the German National Pandemic Cohort Network (NAPKON-SUEP) Open
View article: Continuation of chronic antiplatelet therapy is not associated with increased need for transfusions: a cohort study in critically ill septic patients
Continuation of chronic antiplatelet therapy is not associated with increased need for transfusions: a cohort study in critically ill septic patients Open
Background The decision to maintain or halt antiplatelet medication in septic patients admitted to intensive care units presents a clinical dilemma. This is due to the necessity to balance the benefits of preventing thromboembolic incident…
View article: Comparison of post-COVID-19 symptoms in patients infected with the SARS-CoV- 2 variants delta and omicron - results of the Cross-Sectoral Platform of the German National Pandemic Cohort Network (NAPKON-SUEP)
Comparison of post-COVID-19 symptoms in patients infected with the SARS-CoV- 2 variants delta and omicron - results of the Cross-Sectoral Platform of the German National Pandemic Cohort Network (NAPKON-SUEP) Open
Purpose The influence of new SARS-CoV-2 variants on the post-COVID-19 condition (PCC) remains unanswered. Therefore, we examined the prevalence and predictors of PCC-related symptoms in patients infected with the SARS-CoV-2 variants delta …
View article: Quantity of Work Days Lost Due To Side Effects Among Health Care Workers Vaccinated with Bnt162b2 and Chadox1
Quantity of Work Days Lost Due To Side Effects Among Health Care Workers Vaccinated with Bnt162b2 and Chadox1 Open
View article: Persistent symptoms and risk factors predicting prolonged time to symptom-free after SARS‑CoV‑2 infection: an analysis of the baseline examination of the German COVIDOM/NAPKON-POP cohort
Persistent symptoms and risk factors predicting prolonged time to symptom-free after SARS‑CoV‑2 infection: an analysis of the baseline examination of the German COVIDOM/NAPKON-POP cohort Open
View article: The Greifswald Post COVID Rehabilitation Study and Research (PoCoRe)–Study Design, Characteristics and Evaluation Tools
The Greifswald Post COVID Rehabilitation Study and Research (PoCoRe)–Study Design, Characteristics and Evaluation Tools Open
(1) Background: COVID-19 is often associated with significant long-term symptoms and disability, i.e., the long/post-COVID syndrome (PCS). Even after presumably mild COVID-19 infections, an increasing number of patients seek medical help f…
View article: Sepsis Care, Diagnostics and Quality Management: A Multidisciplinary Cross-Sectional Survey in 73 Countries
Sepsis Care, Diagnostics and Quality Management: A Multidisciplinary Cross-Sectional Survey in 73 Countries Open
View article: 1886. External Validation of the 4C Mortality Score and the qSOFA for Different Variants of Concerns of SARS-CoV-2 Using Data of the NAPKON Cross-Sectoral Cohort Platform (SUEP)
1886. External Validation of the 4C Mortality Score and the qSOFA for Different Variants of Concerns of SARS-CoV-2 Using Data of the NAPKON Cross-Sectoral Cohort Platform (SUEP) Open
Background Numerous predictive clinical scores with varying discriminatory performance have been developed in the context of the current coronavirus disease 2019 (COVID-19) pandemic. To support clinical application, we test the transferabi…
View article: The German National Pandemic Cohort Network (NAPKON): rationale, study design and baseline characteristics
The German National Pandemic Cohort Network (NAPKON): rationale, study design and baseline characteristics Open
View article: Course of disease and risk factors for hospitalization in outpatients with a SARS-CoV-2 infection
Course of disease and risk factors for hospitalization in outpatients with a SARS-CoV-2 infection Open
We analyzed symptoms and comorbidities as predictors of hospitalization in 710 outpatients in North-East Germany with PCR-confirmed SARS-CoV-2 infection. During the first 3 days of infection, commonly reported symptoms were fatigue (71.8%)…
View article: A multifaceted educational intervention improved anti-infectious measures but had no effect on mortality in patients with severe sepsis
A multifaceted educational intervention improved anti-infectious measures but had no effect on mortality in patients with severe sepsis Open
View article: Adverse effects of delayed antimicrobial treatment and surgical source control in adults with sepsis: results of a planned secondary analysis of a cluster-randomized controlled trial
Adverse effects of delayed antimicrobial treatment and surgical source control in adults with sepsis: results of a planned secondary analysis of a cluster-randomized controlled trial Open
View article: The German National Pandemic Cohort Network (NAPKON): rationale, study design and baseline characteristics.
The German National Pandemic Cohort Network (NAPKON): rationale, study design and baseline characteristics. Open
The German government initiated the Network University Medicine (NUM) in early 2020 to improve national research activities on the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pandemic. To this end, 36 German Academic Medic…
View article: Do not forget the blood cultures!
Do not forget the blood cultures! Open
View article: Assessment of a Postharvest Treatment with Pyrimethanil via Thermo-Nebulization in Controlling Storage Rots of Apples
Assessment of a Postharvest Treatment with Pyrimethanil via Thermo-Nebulization in Controlling Storage Rots of Apples Open
Apples are very susceptible to infections from various fungal pathogens during the growing season due to prolonged exposure to environmental influences in the field. Therefore, a strict and targeted fungicide strategy is essential to prote…
View article: Fever and hypothermia represent two populations of sepsis patients and are associated with outside temperature
Fever and hypothermia represent two populations of sepsis patients and are associated with outside temperature Open
Background Fever and hypothermia have been observed in septic patients. Their influence on prognosis is subject to ongoing debates. Methods We did a secondary analysis of a large clinical dataset from a quality improvement trial. A binary …
View article: Machine learning identifies ICU outcome predictors in a multicenter COVID-19 cohort
Machine learning identifies ICU outcome predictors in a multicenter COVID-19 cohort Open
View article: Anti–platelet factor 4 antibodies causing VITT do not cross-react with SARS-CoV-2 spike protein
Anti–platelet factor 4 antibodies causing VITT do not cross-react with SARS-CoV-2 spike protein Open
Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a severe adverse effect of ChAdOx1 nCoV-19 COVID-19 vaccine (Vaxzevria) and Janssen Ad26.COV2.S COVID-19 vaccine, and it is associated with unusual thrombosis. VITT is caused by …
View article: Machine Learning Identifies ICU Outcome Predictors in a Multicenter COVID-19 Cohort.
Machine Learning Identifies ICU Outcome Predictors in a Multicenter COVID-19 Cohort. Open
Background. Intensive Care Resources are heavily utilized during the COVID-19 pandemic. However, risk stratification and prediction of SARS-CoV-2 patient clinical outcomes upon ICU admission remain inadequate. This study aimed to develop a…
View article: Frequency of positive anti-PF4/polyanion antibody tests after COVID-19 vaccination with ChAdOx1 nCoV-19 and BNT162b2
Frequency of positive anti-PF4/polyanion antibody tests after COVID-19 vaccination with ChAdOx1 nCoV-19 and BNT162b2 Open
Vaccination using the adenoviral vector COVID-19 vaccine ChAdOx1 nCoV-19 (AstraZeneca) has been associated with rare vaccine-induced immune thrombotic thrombocytopenia (VITT). Affected patients test strongly positive in platelet factor 4 (…
View article: Anti-SARS-CoV-2 Spike Protein and Anti-Platelet Factor 4 Antibody Responses Induced by COVID-19 Disease and ChAdOx1 nCov-19 vaccination
Anti-SARS-CoV-2 Spike Protein and Anti-Platelet Factor 4 Antibody Responses Induced by COVID-19 Disease and ChAdOx1 nCov-19 vaccination Open
Background: Some recipients of ChAdOx1 nCoV-19 COVID-19 Vaccine AstraZeneca develop antibody-mediated vaccine-induced thrombotic thrombocytopenia (VITT), associated with cerebral venous and other unusual thrombosis resembling autoimmune he…
View article: Randomisierte kontrollierte multizentrische Studie zur Albuminersatztherapie im septischen Schock (ARISS)
Randomisierte kontrollierte multizentrische Studie zur Albuminersatztherapie im septischen Schock (ARISS) Open
View article: Randomized controlled multicentre study of albumin replacement therapy in septic shock (ARISS): protocol for a randomized controlled trial
Randomized controlled multicentre study of albumin replacement therapy in septic shock (ARISS): protocol for a randomized controlled trial Open
View article: Extensive efficacy tests of non-antibiotic fire blight control agents
Extensive efficacy tests of non-antibiotic fire blight control agents Open
Application of control agents to prevent new infections is an integral part of disease management for fire blight on pome trees caused by Erwinia amylovora (Burrill) Winslow et al.. Due to resistance development and human health concerns w…
View article: Additional file 1 of Randomized controlled multicentre study of albumin replacement therapy in septic shock (ARISS): protocol for a randomized controlled trial
Additional file 1 of Randomized controlled multicentre study of albumin replacement therapy in septic shock (ARISS): protocol for a randomized controlled trial Open
Additional file 1.