Sebastian Kufner
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View article: Clinical outcomes of drug-coated balloon vs. second-generation drug-eluting stent for coronary in-stent restenosis
Clinical outcomes of drug-coated balloon vs. second-generation drug-eluting stent for coronary in-stent restenosis Open
Background Current guideline recommendations for the treatment of coronary in-stent restenosis (ISR) are primarily based on evidence from smaller, randomized trials comparing drug-coated balloons (DCBs) and second-generation drug-eluting s…
View article: Association of Body Mass Index on 10-Year Outcomes in Patients Treated with Percutaneous Coronary Intervention and Drug-Eluting Stents (the DECADE Cooperation)
Association of Body Mass Index on 10-Year Outcomes in Patients Treated with Percutaneous Coronary Intervention and Drug-Eluting Stents (the DECADE Cooperation) Open
Aim To assess the association between body mass index (BMI) and 10-year clinical outcomes in patients undergoing percutaneous coronary intervention (PCI) with drug-eluting stent (DES) implantation. Methods This is a pooled analysis of 5 ra…
View article: Correction: Sex-specific outcomes in myocardial infarction: a dual-cohort analysis using clinical and real-world data
Correction: Sex-specific outcomes in myocardial infarction: a dual-cohort analysis using clinical and real-world data Open
View article: Deep learning model DeepNeo predicts neointimal tissue characterization using optical coherence tomography
Deep learning model DeepNeo predicts neointimal tissue characterization using optical coherence tomography Open
Background Accurate interpretation of optical coherence tomography (OCT) pullbacks is critical for assessing vascular healing after percutaneous coronary intervention (PCI). Manual analysis is time-consuming and subjective, highlighting th…
View article: Sex-specific outcomes in myocardial infarction: a dual-cohort analysis using clinical and real-world data
Sex-specific outcomes in myocardial infarction: a dual-cohort analysis using clinical and real-world data Open
Background Sex-related differences in symptoms, treatment, and outcomes in patients presenting with myocardial infarction have been reported but vary largely between studies. We sought to characterize sex differences in presentation and ou…
View article: Smoking Status at Baseline and 10-Year Outcomes After Drug-Eluting Stent Implantation
Smoking Status at Baseline and 10-Year Outcomes After Drug-Eluting Stent Implantation Open
In patients undergoing PCI with DES, smoking at baseline is associated with an increased risk of death, MI, and ST, but a lower risk of repeat revascularization through to 10 years.
View article: Age-related ten-year outcomes after percutaneous coronary intervention of in-stent restenosis
Age-related ten-year outcomes after percutaneous coronary intervention of in-stent restenosis Open
In the long-term, rates of cardiac death after percutaneous coronary intervention of DES-ISR were higher and TLR rates were lower in patients older than 75 years. There was no difference in the rates of MI.
View article: Comparative safety and efficacy of new-generation single-layer polytetrafluorethylene- versus polyurethane-covered stents in patients with coronary artery perforation for the RECOVER (REsults after percutaneous interventions with COVERed stents) Investigators
Comparative safety and efficacy of new-generation single-layer polytetrafluorethylene- versus polyurethane-covered stents in patients with coronary artery perforation for the RECOVER (REsults after percutaneous interventions with COVERed stents) Investigators Open
New-generation single-layer polytetrafluorethylene (PTFE-) or polyurethane (PU-) covered stent (CS) for the treatment of coronary artery perforation (CAP) during PCI offer high procedural efficacy. To evaluate the comparative long-term saf…
View article: Body Mass Index and 10-year Clinical Outcomes After Percutaneous Coronary Intervention - Interaction With Age, Sex, Diabetic Status and Clinical Presentation
Body Mass Index and 10-year Clinical Outcomes After Percutaneous Coronary Intervention - Interaction With Age, Sex, Diabetic Status and Clinical Presentation Open
Background and Aims: The association between body mass index (BMI) and long-term outcome after percutaneous coronary intervention (PCI) remains poorly inves-tigated. We undertook this study to assess the association between BMI and 10-year…
View article: Long-Term Safety and Efficacy Of Rotational Atherectomy for Lesion Preparation of Calcified Coronary Lesionsthe Isar-Rock Registry
Long-Term Safety and Efficacy Of Rotational Atherectomy for Lesion Preparation of Calcified Coronary Lesionsthe Isar-Rock Registry Open
View article: Age-Related Ten-Year Outcomes after Percutaneous Coronary Intervention of In-Stent Restenosis
Age-Related Ten-Year Outcomes after Percutaneous Coronary Intervention of In-Stent Restenosis Open
View article: Intracoronary stenting and additional results achieved by shockWAVE coronary lithotripsy: design and rationale of ISAR-WAVE trial
Intracoronary stenting and additional results achieved by shockWAVE coronary lithotripsy: design and rationale of ISAR-WAVE trial Open
ClilicalTrial.gov, NCT06369142.
View article: Impaired Kidney Function and 10-Year Outcome After Percutaneous Coronary Intervention—Interaction with Age, Sex, Diabetic Status and Clinical Presentation
Impaired Kidney Function and 10-Year Outcome After Percutaneous Coronary Intervention—Interaction with Age, Sex, Diabetic Status and Clinical Presentation Open
Background: Limited evidence exists regarding the association of chronic kidney disease (CKD) with long-term outcomes following percutaneous coronary intervention (PCI). We aimed to assess the association of CKD with 10-year outcome after …
View article: Comparison of strategies for vascular ACCESS closure after Transcatheter Aortic Valve Implantation: the ACCESS-TAVI randomized trial
Comparison of strategies for vascular ACCESS closure after Transcatheter Aortic Valve Implantation: the ACCESS-TAVI randomized trial Open
Background and Aims Data from randomized trials investigating different access closure strategies after transfemoral transcatheter aortic valve implantation (TF-TAVI) remain scarce. In this study, two vascular closure device (VCD) strategi…
View article: Left Ventricular Ejection Fraction Change Following Percutaneous Coronary Intervention: Correlates and Association With Prognosis
Left Ventricular Ejection Fraction Change Following Percutaneous Coronary Intervention: Correlates and Association With Prognosis Open
Background The association between left ventricular ejection fraction (LVEF) change (ΔLVEF) following percutaneous coronary intervention (PCI) and the long‐term mortality rate in patients with coronary artery disease is incompletely invest…
View article: Ten‐year clinical outcomes after drug‐eluting stents implantation according to clinical presentation—Insights from the <scp>DECADE</scp> cooperation
Ten‐year clinical outcomes after drug‐eluting stents implantation according to clinical presentation—Insights from the <span>DECADE</span> cooperation Open
Background Investigations of very long‐term outcomes after percutaneous coronary intervention (PCI) with drug‐eluting stents (DES) according to clinical presentation are scarce. Here, we investigated the 10‐year clinical outcomes of patien…
View article: Tiempos para la revascularización multivaso en pacientes estables con IAMCEST: revisión sistemática y metanálisis en red
Tiempos para la revascularización multivaso en pacientes estables con IAMCEST: revisión sistemática y metanálisis en red Open
View article: DeepNeo: Deep Learning for neointimal tissue characterization using optical coherence tomography
DeepNeo: Deep Learning for neointimal tissue characterization using optical coherence tomography Open
Aims This study aimed to develop a deep-learning algorithm to enable a fully-automated analysis and interpretation of optical coherence tomography (OCT) pull-backs from patients after percutaneous coronary intervention (PCI). Methods and r…
View article: Incidence and pattern of urgent revascularization in acute coronary syndromes treated with ticagrelor or prasugrel
Incidence and pattern of urgent revascularization in acute coronary syndromes treated with ticagrelor or prasugrel Open
Background The ISAR-REACT 5 trial compared the efficacy and safety of ticagrelor and prasugrel in patients with ACS managed invasively. The present study sought to investigate the impact of ticagrelor and prasugrel on the incidence and pat…
View article: A Ten-Year Follow-Up Study of the Association Between Uric Acid and Adverse Cardiovascular Events in Patients With Coronary Artery Disease
A Ten-Year Follow-Up Study of the Association Between Uric Acid and Adverse Cardiovascular Events in Patients With Coronary Artery Disease Open
View article: Coronary no-reflow and adverse events in patients with acute myocardial infarction after percutaneous coronary intervention with current drug-eluting stents and third-generation P2Y12 inhibitors
Coronary no-reflow and adverse events in patients with acute myocardial infarction after percutaneous coronary intervention with current drug-eluting stents and third-generation P2Y12 inhibitors Open
Background The frequency and prognostic value of coronary no-reflow (CNR) was investigated in studies that have used an outdated reperfusion therapy in terms of stent technology and antithrombotic drugs. We assessed the association of CNR …
View article: Modified balloons to prepare severely calcified coronary lesions before stent implantation: a systematic review and meta-analysis of randomized trials
Modified balloons to prepare severely calcified coronary lesions before stent implantation: a systematic review and meta-analysis of randomized trials Open
View article: Incidence and pattern of repeat coronary revascularizations in patients with acute coronary syndromes treated with ticagrelor or prasugrel
Incidence and pattern of repeat coronary revascularizations in patients with acute coronary syndromes treated with ticagrelor or prasugrel Open
Background The ISAR-REACT 5 randomized trial compared the efficacy and safety of ticagrelor and prasugrel in patients with acute coronary syndromes (ACS) managed invasively. Data are missing with regard to the effect of these antiplatelet …
View article: Ten‐year outcomes after percutaneous coronary intervention of in‐stent restenosis in saphenous vein grafts
Ten‐year outcomes after percutaneous coronary intervention of in‐stent restenosis in saphenous vein grafts Open
Background Only few data is available for long‐term outcomes of patients being treated for in‐stent restenosis (ISR) in saphenous vein grafts (SVG). Aims Thus, the aim of this observational, retrospective study was to close this lack of ev…
View article: Correlaci�n fluorosc�pica y tomogr�fica para medir el anillo a�rtico en implante percut�neo de v�lvula a�rtica: regla de c�spide coronaria derecha
Correlaci�n fluorosc�pica y tomogr�fica para medir el anillo a�rtico en implante percut�neo de v�lvula a�rtica: regla de c�spide coronaria derecha Open
RESUMEN Introducción y objetivos: La angiografía por tomografía computarizada (angio-TC) es el estándar para medir el anillo aórtico en pacientes tratados mediante implante percutáneo de válvula aórtica (TAVI), aunque en algunos casos podr…
View article: Derivation and validation of the ISAR score to predict the risk of repeat percutaneous coronary intervention for recurrent drug-eluting stent restenosis
Derivation and validation of the ISAR score to predict the risk of repeat percutaneous coronary intervention for recurrent drug-eluting stent restenosis Open
This study developed and validated a risk prediction model for repeat PCI for recurrent DES-ISR at 1-year follow-up. This model served to generate the ISAR score, a standardised tool that can be used to predict the 1-year risk of repeat PC…
View article: Prevalence and patterns of in-stent neoatherosclerosis in lower extremity artery disease
Prevalence and patterns of in-stent neoatherosclerosis in lower extremity artery disease Open
In-stent NA is frequently identified by OCT imaging after endovascular therapy in lower limb arteries; this increased both in frequency and extent the longer the duration since implantation. Our findings indicate an active atherosclerotic …
View article: Fluoroscopic and tomographic correlation for aortic annulus measurements in transcatheter aortic valve implantation: �follow the right cusp� rule
Fluoroscopic and tomographic correlation for aortic annulus measurements in transcatheter aortic valve implantation: �follow the right cusp� rule Open
Introduction and objectives: Coronary computed tomography angiography (CCTA) has become the gold standard to measure the size of the aortic annulus and better select the size of transcatheter heart valves (THV) in patients undergoing trans…
View article: Coronary artery restenosis treatment with plain balloon, drug-coated balloon, or drug-eluting stent: 10-year outcomes of the ISAR-DESIRE 3 trial
Coronary artery restenosis treatment with plain balloon, drug-coated balloon, or drug-eluting stent: 10-year outcomes of the ISAR-DESIRE 3 trial Open
Aims The best interventional strategy for the treatment of drug-eluting stent (DES) in-stent restenosis (ISR) is still unclear and no data from randomized trials beyond 3-year follow-up are available. We aimed to define 10-year comparative…
View article: Sex Differences in 10-Year Outcomes After Percutaneous Coronary Intervention With Drug-Eluting Stents: Insights From the DECADE Cooperation
Sex Differences in 10-Year Outcomes After Percutaneous Coronary Intervention With Drug-Eluting Stents: Insights From the DECADE Cooperation Open
Background: Although some studies have investigated sex-related outcomes up to 5 years after percutaneous coronary intervention (PCI), analyses at longer follow-up (ie, to 10 years) in large cohorts treated exclusively with drug-eluting st…