Sebastián Vásquez-Sepúlveda
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View article: Environmental stiffness regulates neuronal maturation via Piezo1-mediated transthyretin activity
Environmental stiffness regulates neuronal maturation via Piezo1-mediated transthyretin activity Open
View article: Biphasic inflammation control by fibroblasts enables spinal cord regeneration in zebrafish
Biphasic inflammation control by fibroblasts enables spinal cord regeneration in zebrafish Open
Fibrosis and persistent inflammation are interconnected processes that inhibit axon regeneration in the mammalian central nervous system (CNS). Here, we show that in zebrafish, the interplay between fibroblasts and immune cells is required…
View article: Biphasic inflammation control by dedifferentiated fibroblasts enables axon regeneration after spinal cord injury in zebrafish
Biphasic inflammation control by dedifferentiated fibroblasts enables axon regeneration after spinal cord injury in zebrafish Open
Fibrosis and persistent inflammation are interconnected processes that inhibit axon regeneration in the mammalian central nervous system (CNS). In zebrafish, by contrast, fibroblast-derived extracellular matrix deposition and inflammation …
View article: AI-assisted imaging screening reveals mechano-molecular tissue organizers and network of signaling hubs
AI-assisted imaging screening reveals mechano-molecular tissue organizers and network of signaling hubs Open
Cadherin-mediated adhesions are crucial mechanical and signaling hubs that connect cells within a tissue and probe the mechanics of the surrounding environment. They constitute a physical link between the actin cytoskeleton of neighboring …
View article: Environmental stiffness regulates neuronal maturation via Piezo1-mediated TTR activity
Environmental stiffness regulates neuronal maturation via Piezo1-mediated TTR activity Open
During brain development, neurons extend axons to connect to their target cells while initiating a maturation process during which neurons start expressing voltage-gated ion channels, form synapses, express synaptic transmitters and recept…
View article: Protocol for extracting live blastoderm cells from embryos of annual killifish
Protocol for extracting live blastoderm cells from embryos of annual killifish Open