Sebastian Zimny
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View article: The acidic microenvironment in the perisinusoidal space critically determines bile salt-induced activation of hepatic stellate cells
The acidic microenvironment in the perisinusoidal space critically determines bile salt-induced activation of hepatic stellate cells Open
View article: Medical care of patients with Wilson disease in Germany: a multidisciplinary survey among university centers
Medical care of patients with Wilson disease in Germany: a multidisciplinary survey among university centers Open
View article: Hydrophobic Bile Salts Induce Pro-Fibrogenic Proliferation of Hepatic Stellate Cells through PI3K p110 Alpha Signaling
Hydrophobic Bile Salts Induce Pro-Fibrogenic Proliferation of Hepatic Stellate Cells through PI3K p110 Alpha Signaling Open
Bile salts accumulating during cholestatic liver disease are believed to promote liver fibrosis. We have recently shown that chenodeoxycholate (CDC) induces expansion of hepatic stellate cells (HSCs) in vivo, thereby promoting liver fibros…
View article: Multidisciplinary lifestyle intervention is associated with improvements in liver damage and in surrogate scores of NAFLD and liver fibrosis in morbidly obese patients
Multidisciplinary lifestyle intervention is associated with improvements in liver damage and in surrogate scores of NAFLD and liver fibrosis in morbidly obese patients Open
View article: Supplementary Material for: The Psychosocial Burden on Liver Transplant Recipients during the COVID-19 Pandemic
Supplementary Material for: The Psychosocial Burden on Liver Transplant Recipients during the COVID-19 Pandemic Open
Introduction: Due to the coronavirus disease 19 (COVID-19) pandemic, multiple measures have been implemented including social distancing and curfews. Both the disease and measures might cause stress, particularly in persons a…
View article: The Psychosocial Burden on Liver Transplant Recipients during the COVID-19 Pandemic
The Psychosocial Burden on Liver Transplant Recipients during the COVID-19 Pandemic Open
Introduction: Due to the coronavirus disease 19 (COVID-19) pandemic, multiple measures have been implemented including social distancing and curfews. Both the disease and measures might cause stress, particularly in persons a…
View article: Chemerin-156 is the Active Isoform in Human Hepatic Stellate Cells
Chemerin-156 is the Active Isoform in Human Hepatic Stellate Cells Open
The chemokine chemerin exists as C-terminally processed isoforms whose biological functions are mostly unknown. A highly active human chemerin variant (huChem-157) was protective in experimental hepatocellular carcinoma (HCC) models. Hepat…
View article: Hydrophobic bile acids promote proliferation and activation of hepatic stellate cells by PI3K-dependent mechanisms
Hydrophobic bile acids promote proliferation and activation of hepatic stellate cells by PI3K-dependent mechanisms Open