Sébastien Déglise
YOU?
Author Swipe
View article: Comprehensive characterization of early-stage Non-Small Cell Lung cancers with multi-modal data integration
Comprehensive characterization of early-stage Non-Small Cell Lung cancers with multi-modal data integration Open
Non-small cell lung cancer (NSCLC) is one of the leading causes of cancer-related death despite the availability of therapies targeting the tumor microenvironment (TME) and/or the tumor. Immunotherapy and novel targeted therapy have improv…
View article: Correction: Tortuosity in non-atherosclerotic vascular diseases is associated with age, arterial aneurysms, and hypertension
Correction: Tortuosity in non-atherosclerotic vascular diseases is associated with age, arterial aneurysms, and hypertension Open
View article: Multi-modal image analysis for large-scale cancer tissue studies within IMMUcan
Multi-modal image analysis for large-scale cancer tissue studies within IMMUcan Open
In cancer research, multiplexed imaging allows detailed characterization of the tumor microenvironment (TME) and its link to patient prognosis. The integrated immunoprofiling of large adaptive cancer patient cohorts (IMMUcan) consortium co…
View article: Hydrogen sulfide aggravates neutrophil infiltration, vascular remodeling and elastase-induced abdominal aortic aneurysm in male mice
Hydrogen sulfide aggravates neutrophil infiltration, vascular remodeling and elastase-induced abdominal aortic aneurysm in male mice Open
View article: Stimulating angiogenesis and post-ischemic tissue repair: Optimizing photobiomodulation parameters in vivo
Stimulating angiogenesis and post-ischemic tissue repair: Optimizing photobiomodulation parameters in vivo Open
View article: Human Saphenous Vein Ex Vivo Culture as a Translational Model of Intimal Hyperplasia
Human Saphenous Vein Ex Vivo Culture as a Translational Model of Intimal Hyperplasia Open
BACKGROUND Intimal hyperplasia (IH) significantly limits the long-term patency of saphenous vein grafts following bypass surgery, with no human models available to fully understand its complex pathogenesis. Although animal models, primaril…
View article: 2024 ESC Guidelines for the management of peripheral arterial and aortic diseases (Translation of the summary of the document prepared by the Czech Society of Angiology, 2025)
2024 ESC Guidelines for the management of peripheral arterial and aortic diseases (Translation of the summary of the document prepared by the Czech Society of Angiology, 2025) Open
View article: 2024 ESC Guidelines for the management of peripheral arterial and aortic diseases (Translation of the shortened document prepared by the Czech Society of Cardiology)
2024 ESC Guidelines for the management of peripheral arterial and aortic diseases (Translation of the shortened document prepared by the Czech Society of Cardiology) Open
View article: Association of Kidney Graft Long-term Outcome With Recipient Cystathionine Gamma-lyase Polymorphisms and Hydrogen Sulfide Levels: A Cohort Study
Association of Kidney Graft Long-term Outcome With Recipient Cystathionine Gamma-lyase Polymorphisms and Hydrogen Sulfide Levels: A Cohort Study Open
Background. Hydrogen sulfide (H 2 S) produced endogenously by the CTH gene-encoded cystathionine gamma-lyase protects from renal ischemia–reperfusion injury in preclinical models. Here, we hypothesized that CTH gene polymorphisms (single n…
View article: Case Report: Unlocking arteria Lusoria challenges: sternotomy's role in a single-stage aneurysm repair and artery realignment
Case Report: Unlocking arteria Lusoria challenges: sternotomy's role in a single-stage aneurysm repair and artery realignment Open
Arteria lusoria (AL), an anomaly of the right subclavian artery, occurs in 2% of individuals and can cause symptoms such as dysphagia due to its retroesophageal course. Often associated with Kommerell's diverticulum (KD), a dilation at the…
View article: A Prospective, Multicentre Registry on Thirty Day and One Year Outcomes of the E-liac Stent Graft System in Patients with Unilateral or Bilateral Aorto-iliac or Iliac Aneurysms: The PLIANTII Study
A Prospective, Multicentre Registry on Thirty Day and One Year Outcomes of the E-liac Stent Graft System in Patients with Unilateral or Bilateral Aorto-iliac or Iliac Aneurysms: The PLIANTII Study Open
The one year data from the PLIANTII study show that treatment with the E-liac stent graft system is safe and results in good technical and clinical success rates.
View article: Multi-modal image analysis for large scale cancer tissue studies within IMMUcan
Multi-modal image analysis for large scale cancer tissue studies within IMMUcan Open
Motivation Multiplexed imaging is increasingly used to study tissue architecture in health and disease. To investigate the cancer tumor microenvironment, typically either tissue micro-arrays or small patient cohorts are used to collect and…
View article: [2024 ESC Guidelines for the management of peripheral arterial and aortic diseases].
[2024 ESC Guidelines for the management of peripheral arterial and aortic diseases]. Open
peer reviewed
View article: Optimizing Photobiomodulation Radiometric and Spectral Parameters In Vitro to Enhance Angiogenesis and Mitochondrial Function
Optimizing Photobiomodulation Radiometric and Spectral Parameters In Vitro to Enhance Angiogenesis and Mitochondrial Function Open
Photobiomodulation (PBM) therapy, a therapeutic approach utilizing low-level light, has garnered significant attention for its potential to modulate various biological processes. This study aimed at optimizing and investigating the effects…
View article: Nicotinamide mononucleotide restores impaired metabolism, endothelial cell proliferation and angiogenesis in old sedentary male mice
Nicotinamide mononucleotide restores impaired metabolism, endothelial cell proliferation and angiogenesis in old sedentary male mice Open
View article: Dietary or pharmacological inhibition of insulin-like growth factor-1 protects from renal ischemia-reperfusion injury in mice
Dietary or pharmacological inhibition of insulin-like growth factor-1 protects from renal ischemia-reperfusion injury in mice Open
View article: Retraction Notice to “Predictive Factors of Surgical Complications in the First Year Following Kidney Transplantation” [Annals of Vascular Surgery 83 (2022) 142-151]
Retraction Notice to “Predictive Factors of Surgical Complications in the First Year Following Kidney Transplantation” [Annals of Vascular Surgery 83 (2022) 142-151] Open
View article: 2024 ESC Guidelines for the management of peripheral arterial and aortic diseases
2024 ESC Guidelines for the management of peripheral arterial and aortic diseases Open
peer reviewed
View article: Tortuosity in non-atherosclerotic vascular diseases is associated with age, arterial aneurysms, and hypertension
Tortuosity in non-atherosclerotic vascular diseases is associated with age, arterial aneurysms, and hypertension Open
Background Increased arterial tortuosity has been associated with various cardiovascular complications. However, the extent and role of arterial tortuosity in non-atherosclerotic vascular diseases remain to be fully elucidated. This study …
View article: Mobile vs Fixed Fluoroscopy System for EVAR Image Quality and Radiation Doses for Patients and Professionnals: Mobile C-Arm vs Hybrid Room for EVAR
Mobile vs Fixed Fluoroscopy System for EVAR Image Quality and Radiation Doses for Patients and Professionnals: Mobile C-Arm vs Hybrid Room for EVAR Open
Background Allowing less invasive treatments, endovascular aortic repair (EVAR) has become the gold standard worldwide for the treatment of abdominal aortic aneurysms, leading to questions regarding staff and patients’ exposure to radiatio…
View article: Endovascular Treatment of Complex Aortic Aneurysms Using Inner Branch Device (IBEVAR): A Single Center Experience
Endovascular Treatment of Complex Aortic Aneurysms Using Inner Branch Device (IBEVAR): A Single Center Experience Open
Background Due to advances in devices and techniques, the endovascular approach using fenestrated or branched endografts has emerged as a valid and safe alternative for patients with complex aortic aneurysms, especially if considered at hi…
View article: Modified Gritti–Stokes amputation: tips and tricks
Modified Gritti–Stokes amputation: tips and tricks Open
Major amputations of the lower extremity may be required after trauma and a variety of underlying diseases such as peripheral vascular disease, diabetes, and malignancies. The goal of any major amputation is an optimal functional result wi…
View article: Short-term hypercaloric carbohydrate loading increases surgical stress resilience by inducing FGF21
Short-term hypercaloric carbohydrate loading increases surgical stress resilience by inducing FGF21 Open
Dietary restriction promotes resistance to surgical stress in multiple organisms. Counterintuitively, current medical protocols recommend short-term carbohydrate-rich drinks (carbohydrate loading) prior to surgery, part of a multimodal per…
View article: Impaired glycolysis in aged endothelial cells is associated with reduced neovascularisation upon tissue ischemia
Impaired glycolysis in aged endothelial cells is associated with reduced neovascularisation upon tissue ischemia Open
The vascular system experiences an age-associated decline in tissue perfusion and response to ischemic diseases. The factors driving this age-associated neovascularization decline remain unclear. While old endothelial cells (ECs) adopt a p…
View article: Midterm Outcomes With the Nellix Endograft Alone or With Chimneys
Midterm Outcomes With the Nellix Endograft Alone or With Chimneys Open
View article: 199P Scalable multiplexed image analysis across cancer types as part of the IMMUcan consortium
199P Scalable multiplexed image analysis across cancer types as part of the IMMUcan consortium Open
View article: 1P Integrated data analysis within IMMUcan identifies prognostic features of early NSCLC
1P Integrated data analysis within IMMUcan identifies prognostic features of early NSCLC Open
The advent of personalized medicine and ever-increasing numbers of available cancer drugs necessitate better prognostic and predictive biomarkers. In turn, this requires a deeper profiling and understanding of tumors and the tumor microenv…
View article: Sodium Hydrosulfide Treatment During Porcine Kidney Ex Vivo Perfusion and Transplantation
Sodium Hydrosulfide Treatment During Porcine Kidney Ex Vivo Perfusion and Transplantation Open
Background. In rodents, hydrogen sulfide (H 2 S) reduces ischemia-reperfusion injury and improves renal graft function after transplantation. Here, we hypothesized that the benefits of H 2 S are conserved in pigs, a more clinically relevan…
View article: Unlocking Arteria Lusoria Challenges: Sternotomy's Role in a Single-Stage Aneurysm Repair and Artery Realignment.
Unlocking Arteria Lusoria Challenges: Sternotomy's Role in a Single-Stage Aneurysm Repair and Artery Realignment. Open
This study presents a case report demonstrating an anomalous origin of the right subclavian artery from the aortic arch, accompanied by proximal dilation and a retro-esophageal course, characteristic of arteria lusoria and Kommerell's…
View article: Lymph node dendritic cells harbor inducible replication-competent HIV despite years of suppressive ART
Lymph node dendritic cells harbor inducible replication-competent HIV despite years of suppressive ART Open
Although gut and lymph node (LN) memory CD4 T cells represent major HIV and simian immunodeficiency virus (SIV) tissue reservoirs, the study of the role of dendritic cells (DCs) in HIV persistence has long been limited to the blood due to …