Seef Abdalla
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View article: A Rapid Lc-Ms/Ms Method for the Simultaneous Quantification of Ivacaftor, Lumacaftor, Elexacaftor, Tezacaftor, Hexyl-Methyl Ivacaftor and Ivacaftor Carboxylate in Human Plasma
A Rapid Lc-Ms/Ms Method for the Simultaneous Quantification of Ivacaftor, Lumacaftor, Elexacaftor, Tezacaftor, Hexyl-Methyl Ivacaftor and Ivacaftor Carboxylate in Human Plasma Open
View article: Simultaneous pharmacokinetic modeling of unbound and total darunavir with ritonavir in adolescents: a substudy of the SMILE trial
Simultaneous pharmacokinetic modeling of unbound and total darunavir with ritonavir in adolescents: a substudy of the SMILE trial Open
Darunavir (DRV) is an HIV protease inhibitor commonly used as part of antiretroviral treatment regimens globally for children and adolescents. It requires a pharmacological booster, such as ritonavir (RTV) or cobicistat. To better understa…
View article: Population Pharmacokinetics of Intravenous and Oral Acyclovir and Oral Valacyclovir in Pediatric Population To Optimize Dosing Regimens
Population Pharmacokinetics of Intravenous and Oral Acyclovir and Oral Valacyclovir in Pediatric Population To Optimize Dosing Regimens Open
Acyclovir is an antiviral currently used for the prevention and treatment of herpes simplex virus (HSV) and varicella-zoster virus (VZV) infections. This study aimed to characterize the pharmacokinetics (PK) of acyclovir and its oral prodr…