Salwa Masud
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View article: <i>In vivo</i> mRNA delivery to the lung vascular endothelium by dicationic Charge-Altering Releasable Transporters
<i>In vivo</i> mRNA delivery to the lung vascular endothelium by dicationic Charge-Altering Releasable Transporters Open
Endothelial cells (EC) comprise the pulmonary vascular bed and play a significant role in health and disease. Consequently, the EC niche represents an attractive therapeutic target for treating a wide range of pulmonary vascular diseases. …
View article: Excessive Postnatal Smooth Muscle Differentiation in a Lung Specific Model of <i>TBX4</i> -related Pulmonary Hypertension
Excessive Postnatal Smooth Muscle Differentiation in a Lung Specific Model of <i>TBX4</i> -related Pulmonary Hypertension Open
Heterozygous TBX4 variants are the second most common genetic cause of pediatric pulmonary hypertension (PH), yet the mechanisms underlying the pathophysiology of TBX4-related lung disease remain poorly understood. We developed a lung mese…
View article: U.S. payer budget impact of using an AI-augmented cancer risk discrimination digital histopathology platform to identify high-risk of recurrence in women with early-stage invasive breast cancer
U.S. payer budget impact of using an AI-augmented cancer risk discrimination digital histopathology platform to identify high-risk of recurrence in women with early-stage invasive breast cancer Open
Sensitivity analyses demonstrated robust overall savings to changes in all variables in the model. The use of PDxBr to assess breast cancer recurrence risk has the potential to fill gaps in care and reduce costs when gene expression signat…
View article: US payer budget impact of a microarray assay with machine learning to evaluate kidney transplant rejection in for-cause biopsies
US payer budget impact of a microarray assay with machine learning to evaluate kidney transplant rejection in for-cause biopsies Open
Compared with histologic evaluation of for-cause kidney transplant biopsies alone, the use of MMDx-Kidney in conjunction with histologic evaluation improves the diagnoses of graft dysfunction and may have the potential to generate overall …
View article: Preserving Wideband Tympanometry Information With Artifact Mitigation
Preserving Wideband Tympanometry Information With Artifact Mitigation Open
Objective: Absorbance measured using wideband tympanometry (WBT) has been shown to be sensitive to changes in middle and inner ear mechanics, with potential to diagnose various mechanical ear pathologies. However, artifacts in absorbance d…
View article: Mechanics of Total Drum Replacement Tympanoplasty Studied With Wideband Acoustic Immittance
Mechanics of Total Drum Replacement Tympanoplasty Studied With Wideband Acoustic Immittance Open
Objective Poor hearing outcomes often persist following total drum replacement tympanoplasty. To understand the mechanics of the reconstructed eardrum, we measured wideband acoustic immittance and compared the mechanical characteristics of…
View article: Infrasound transmission in the human ear: Implications for acoustic and vestibular responses of the normal and dehiscent inner ear
Infrasound transmission in the human ear: Implications for acoustic and vestibular responses of the normal and dehiscent inner ear Open
The transmission of infrasound within the human ear is not well understood. To investigate infrasound propagation through the middle and inner ear, velocities of the stapes and round window membrane were measured to very low frequencies (d…
View article: The effect of middle ear cavity and superior canal dehiscence on wideband acoustic immittance in fresh human cadaveric specimens
The effect of middle ear cavity and superior canal dehiscence on wideband acoustic immittance in fresh human cadaveric specimens Open
Superior canal dehiscence (SCD) is a hole in the bony wall of the superior semicircular canal, which can cause various auditory and/or vestibular symptoms and can result in wrong and/or delayed diagnosis. Wideband acoustic immittance (WAI)…
View article: Coordinated regulation of acid resistance in Escherichia coli
Coordinated regulation of acid resistance in Escherichia coli Open
Our data suggest that the regulatory network underlying AR is complex and deeply interconnected with the regulation of GABA and glutamate metabolism, nitrogen metabolism. These connections underlie and experimentally validated model of AR1…
View article: Additional file 3: of Coordinated regulation of acid resistance in Escherichia coli
Additional file 3: of Coordinated regulation of acid resistance in Escherichia coli Open
Peaks called and bound and gene expression data for Nac. (XLSX 466 kb)
View article: Additional file 4: of Coordinated regulation of acid resistance in Escherichia coli
Additional file 4: of Coordinated regulation of acid resistance in Escherichia coli Open
Peaks called for NtrC. (XLSX 11.1 kb)
View article: Additional file 2: of Coordinated regulation of acid resistance in Escherichia coli
Additional file 2: of Coordinated regulation of acid resistance in Escherichia coli Open
Peaks called and bound and gene expression data for CsiR. (XLSX 410 kb)
View article: Additional file 5: of Coordinated regulation of acid resistance in Escherichia coli
Additional file 5: of Coordinated regulation of acid resistance in Escherichia coli Open
Peaks called and gene expression data for ompR. (XLSX 28.0 kb)