Sehrish Zaffar
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View article: Emergence of Azithromycin-resistant Salmonella Typhi in Southeast Asia: A systematic review
Emergence of Azithromycin-resistant Salmonella Typhi in Southeast Asia: A systematic review Open
Objective: To systematically review the literature on the epidemiology, antimicrobial resistance, and control strategies for typhoid fever, focusing on Southeast Asia, where the disease burden and emergence of drug-resistant strains are si…
View article: Variation in the <i>ABC</i> transporter genes and association with clinical outcomes in colorectal cancer: a brief review
Variation in the <i>ABC</i> transporter genes and association with clinical outcomes in colorectal cancer: a brief review Open
Colorectal cancer is one of the most prevalent cancers worldwide. We have thus focused on studies on the association of genetic polymorphisms with treatment response and adverse effects in colorectal cancer patients. This review highlights…
View article: Patients’ Preference in Selecting a Dental Practitioner based on Gender
Patients’ Preference in Selecting a Dental Practitioner based on Gender Open
Objective: To examine the prevalence of gender-based selection of dental practitioners among male and female patients in the Out Patient Department (OPD) of the Institute of Dentistry, CMH Lahore Medical College, and to identify factors in…
View article: Comparison of antibody responses of heterologous and homologous Covid-19 booster vaccination: an observational study
Comparison of antibody responses of heterologous and homologous Covid-19 booster vaccination: an observational study Open
Objective Pakistan has been seriously affected by the COVID-19 pandemic, with numerous waves of infection. Using different vaccine and booster doses was a key component to control and combat this pandemic. This study aims to monitor the he…
View article: Comparison of the Effect of Dipeptidyl Peptidase-4 Inhibitors Sitagliptin and Vildagliptin on Intestinal Motility of Rabbit Ileum and Rat Gastric Fundus Tissue
Comparison of the Effect of Dipeptidyl Peptidase-4 Inhibitors Sitagliptin and Vildagliptin on Intestinal Motility of Rabbit Ileum and Rat Gastric Fundus Tissue Open
Background: Diabetes mellitus is a pervasive metabolic disorder. Its prevalence is very high all over the world. Long-standing disease may result in many complications including diabetic gastroparesis. Research to evaluate the impact of an…
View article: Effects of <em>Ziziphus</em> Honey on Bone Healing of the Extracted Tooth Socket by Evaluating Osteopontin Levels
Effects of <em>Ziziphus</em> Honey on Bone Healing of the Extracted Tooth Socket by Evaluating Osteopontin Levels Open
Extraction tooth, Honey, Osteopontin, Ziziphus, Bone healing.
View article: Assessment of Self-Medication Practices among Undergraduate Students Before and During COVID-19
Assessment of Self-Medication Practices among Undergraduate Students Before and During COVID-19 Open
Objective: To assess self-medication knowledge, prevalence, reasons, and conditions among undergraduate medical students. Material and Methods: A survey was conducted among 329 undergraduate healthcare students in tertiary care hospitals &…
View article: The Bronchodilator Potential of Astragalus sarcocolla: An in vitro Experiment
The Bronchodilator Potential of Astragalus sarcocolla: An in vitro Experiment Open
Objective: To evaluate the bronchodilatory mechanism of Astragalus sarcocolla (ASE) extract on tracheal smooth muscles of rabbits.Study Design: In-vitro experimental study.
View article: Comparative IgG Antibody Titers Following Second Dose of Sinopharm and Pfizer Vaccination
Comparative IgG Antibody Titers Following Second Dose of Sinopharm and Pfizer Vaccination Open
Background and Objective: The vaccines Sinopharm and Pfizer account for more than 7.3 billion vaccinations across the globe. Study data shows that the protection offered by these vaccines wanes with time, which is why the third dose of a d…
View article: Vasorelaxant Properties of Moringa oleiferaleaf extract: An in-vitro study on mice blood vessels
Vasorelaxant Properties of Moringa oleiferaleaf extract: An in-vitro study on mice blood vessels Open
Background: Moringa oleifera is a plant rich in bioactive compounds, including flavonoids, polyphenols, and alkaloids, which have been shown to have numerous health benefits. In recent years, several studies have investigated the potential…
View article: Impact of Sleep Deprivation on Academic Performance of Nursing Students at CMH, Lahore
Impact of Sleep Deprivation on Academic Performance of Nursing Students at CMH, Lahore Open
Objective: The objective was to establish a quantifiable link between sleep depression and GPA of nursing students. Study Design: This is a cross sectional, observational analytical study. Place and duration: It was conducted in CMH Lahore…
View article: Effect of Honey on levels of BMP-2 in post-extraction tooth sockets in Humans
Effect of Honey on levels of BMP-2 in post-extraction tooth sockets in Humans Open
Background: In Pakistan, many people undergo tooth extractions every year due to various causes such as dental caries, periodontitis, and trauma. For a healthy alveolar bone after tooth extraction, some kind of intervention is always requi…
View article: Ajwa date (Phoenix dactylifera L.) is hepatoprotective against toxicity by antituberculosis drugs - an experimental study
Ajwa date (Phoenix dactylifera L.) is hepatoprotective against toxicity by antituberculosis drugs - an experimental study Open
Background and Objective: Hepatotoxicity induced by antituberculosis drugs is quite common and often linked with oxidative stress. Ajwa dates are rich in antioxidants and flavonoids; therefore, these may be protective against the oxidative…
View article: Rasagiline Pharmacokinetics in CYP1A2 Variant Healthy Smokers & Non-smokers in Different Doses
Rasagiline Pharmacokinetics in CYP1A2 Variant Healthy Smokers & Non-smokers in Different Doses Open
Objectives: Rasagiline, a drug for Parkinson’s disease is metabolized by CYP1A2 enzyme. The objective of the study was to investigate the influence of cytochrome P450 1A2 variants and smoking status of healthy individuals on the pharmacoki…
View article: Fight against Covid-19: Nigella sativa, a Potential Curative
Fight against Covid-19: Nigella sativa, a Potential Curative Open
COVID-19 has rampaged across continents and has caused a devastating impact on life, economy, mobility, and health. Vaccines are still under clinical trials however there is no immediate solution or drug at hand for effective treatment. Du…
View article: Malus Domestica Peel Extract Counters Carboplatin Induced Fall in Red Blood Cell Count and Bone Marrow Erythroid Cell Percentage in Mice
Malus Domestica Peel Extract Counters Carboplatin Induced Fall in Red Blood Cell Count and Bone Marrow Erythroid Cell Percentage in Mice Open
Introduction: The Chemotherapy-Induced Anemia (CIA) is a complex phenomenon impacted by many treatments and patient related variables. Some variations within CIA are type of chemotherapeutic agent, dose and schedule of administration of ag…
View article: The Spasmolytic Effect of Astragalus Sarcocolla on the Intestinal Smooth Muscles of Rabbit In Vitro: Potassium Channel Opening
The Spasmolytic Effect of Astragalus Sarcocolla on the Intestinal Smooth Muscles of Rabbit In Vitro: Potassium Channel Opening Open
Introduction Astragalus species have been widely used in Chinese herbal medicine to treat gastrointestinal and inflammatory disorders. This study was conducted to evaluate the efficacy of Astragalus sarcocolla (ASE) and to rationalize its …
View article: Development of Resistance Against Mefloquine Prophylaxis in Peace-Keeping Forces in the Central African Republic
Development of Resistance Against Mefloquine Prophylaxis in Peace-Keeping Forces in the Central African Republic Open
Objective To record the frequency of malaria-like symptoms in patients who have been given mefloquine as chemoprophylaxis and to determine the effectiveness of antimalarials against these symptoms. Methodology It was an observational study…
View article: EFFECT OF APPLE PEEL EXTRACT ON THE PRODUCTION OF IgG IMMUNOGLOBULINS IN IMMUNOSUPPRESSED MICE
EFFECT OF APPLE PEEL EXTRACT ON THE PRODUCTION OF IgG IMMUNOGLOBULINS IN IMMUNOSUPPRESSED MICE Open
Objective: To determine the effect of apple peel extract on serum IgG levels in corticosteroid induced immunosuppression in mice. Methodology: Twenty four Swiss albino mice were divided into four groups, with six animals in each group. G…
View article: EFFECT OF JUSTICIA ADHATODA (MALABAR NUT) LEAF EXTRACT ON DRUG-INDUCED COAGULOPATHY IN MICE AND IN-VITRO PLATELET AGGREGATION OF HUMAN BLOOD
EFFECT OF JUSTICIA ADHATODA (MALABAR NUT) LEAF EXTRACT ON DRUG-INDUCED COAGULOPATHY IN MICE AND IN-VITRO PLATELET AGGREGATION OF HUMAN BLOOD Open
Statement of Problem: Oral antiplatelet and anticoagulant drugs are commonly prescribed to patients with cardiovascular diseases. Despite being life-saving, these drugs have one major adverse effect that they can cause spontaneous hemorrha…