Sei J. Lee
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View article: Development of a Mortality Prediction Model for Incarcerated Adults to Identify Palliative Care Needs
Development of a Mortality Prediction Model for Incarcerated Adults to Identify Palliative Care Needs Open
Background Estimating mortality risk in incarcerated adults is important for identifying individuals who may benefit from palliative care and compassionate release referrals. Objective To develop and internally validate a 2-year mortality …
View article: Burden of Hypoglycemia and Hyperglycemia in Insulin‐Treated Veterans Affairs Nursing Home Residents
Burden of Hypoglycemia and Hyperglycemia in Insulin‐Treated Veterans Affairs Nursing Home Residents Open
Background To avoid potential harms from hypoglycemia, guidelines for diabetes management in nursing home residents recommend less intensive glycemic control. However, it is unknown how often hypoglycemia and hyperglycemia co‐occur in the …
View article: Burden of Hypoglycemia and Hyperglycemia in Insulin‐Treated Veterans Affairs Nursing Home Residents
Burden of Hypoglycemia and Hyperglycemia in Insulin‐Treated Veterans Affairs Nursing Home Residents Open
Background To avoid potential harms from hypoglycemia, guidelines for diabetes management in nursing home residents recommend less intensive glycemic control. However, it is unknown how often hypoglycemia and hyperglycemia co‐occur in the …
View article: Urinary incontinence in US adults aged ≥55 years with type 2 diabetes and indications for SGLT2is: NHANES 2013–2020
Urinary incontinence in US adults aged ≥55 years with type 2 diabetes and indications for SGLT2is: NHANES 2013–2020 Open
Objective Sodium-glucose cotransporter-2 inhibitors (SGLT2is) are recommended as first-line cardiorenal protective therapy in type 2 diabetes. Because SGLT2is cause glycosuria and increase urine volume, they may exacerbate incontinence sym…
View article: External Validation of the Walter Index for Posthospitalization Mortality Prediction in Older Adults
External Validation of the Walter Index for Posthospitalization Mortality Prediction in Older Adults Open
Importance The Walter Index is a widely used prognostic tool for assessing 12-month mortality risk among hospitalized older adults. Developed in the US in 2001, its accuracy in contemporary non-US contexts is unclear. Objective To evaluate…
View article: URINARY INCONTINENCE IN US ADULTS WITH DIABETES WHO ARE GUIDELINE-RECOMMENDED TO RECEIVE SGLT2IS: NHANES 2013–2020
URINARY INCONTINENCE IN US ADULTS WITH DIABETES WHO ARE GUIDELINE-RECOMMENDED TO RECEIVE SGLT2IS: NHANES 2013–2020 Open
Sodium-glucose cotransporter-2 inhibitors (SGLT2is) are now recommended as first-line cardiorenal protective therapy for many adults with type 2 diabetes but are also associated with increased risk of urogenital infections. While urinary i…
View article: TESTING ERADAR: A NEW EHR-BASED ALGORITHM TO INCREASE DEMENTIA RECOGNITION IN HEALTH CARE SYSTEMS
TESTING ERADAR: A NEW EHR-BASED ALGORITHM TO INCREASE DEMENTIA RECOGNITION IN HEALTH CARE SYSTEMS Open
Electronic health records (EHRs) hold potential for identifying individuals with undiagnosed dementia. Using machine learning, our team developed and externally validated a predictive algorithm called the EHR Risk of Alzheimers and Dementi…
View article: Antihypertensive Deprescribing and Cardiovascular Events Among Long-Term Care Residents
Antihypertensive Deprescribing and Cardiovascular Events Among Long-Term Care Residents Open
Importance The practice of deprescribing antihypertensive medications is common among long-term care residents, yet the effect on cardiovascular outcomes is unclear. Objective To compare the incidence of hospitalization for myocardial infa…
View article: Delirium risk profiles in a population‐based study of United States older adults undergoing common noncardiac surgeries
Delirium risk profiles in a population‐based study of United States older adults undergoing common noncardiac surgeries Open
Background Older adults often require surgical care and are at elevated risk of delirium. We explored delirium risk profiles across the population of U.S. older adults who underwent one of 10 common noncardiac surgeries. Methods We analyze…
View article: Deprescribing of Antihypertensive Medications and Cognitive Function in Nursing Home Residents
Deprescribing of Antihypertensive Medications and Cognitive Function in Nursing Home Residents Open
Importance Antihypertensive medication deprescribing is common among nursing home residents, yet its association with cognitive decline remains uncertain. Objective To investigate the association of deprescribing antihypertensive medicatio…
View article: Antihypertensive Medication and Fracture Risk in Older Veterans Health Administration Nursing Home Residents
Antihypertensive Medication and Fracture Risk in Older Veterans Health Administration Nursing Home Residents Open
Importance Limited evidence exists on the association between initiation of antihypertensive medication and risk of fractures in older long-term nursing home residents. Objective To assess the association between antihypertensive medicatio…
View article: Reply to: Disease latency and new‐user versus prevalent‐user cohort designs: Implications for pharmacoepidemiology in dementia
Reply to: Disease latency and new‐user versus prevalent‐user cohort designs: Implications for pharmacoepidemiology in dementia Open
This letter comments on the letter by Wu and Swardfager in this issue.
View article: Development and External Validation of Models to Predict Need for Nursing Home Level of Care in Community-Dwelling Older Adults With Dementia
Development and External Validation of Models to Predict Need for Nursing Home Level of Care in Community-Dwelling Older Adults With Dementia Open
Importance Most older adults living with dementia ultimately need nursing home level of care (NHLOC). Objective To develop models to predict need for NHLOC among older adults with probable dementia using self-report and proxy reports to ai…
View article: Around the <scp>EQUATOR</scp> with <scp>Clin‐STAR</scp> : Prediction modeling opportunities and challenges in aging research
Around the <span>EQUATOR</span> with <span>Clin‐STAR</span> : Prediction modeling opportunities and challenges in aging research Open
The 2015 Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis (TRIPOD) Statement was published to improve reporting transparency for prediction modeling studies. The objective of this review is to…
View article: Time to Benefit of Surgery vs Targeted Medical Therapy for Patients With Primary Aldosteronism: A Meta-analysis
Time to Benefit of Surgery vs Targeted Medical Therapy for Patients With Primary Aldosteronism: A Meta-analysis Open
Context Primary aldosteronism (PA) is one of the most common causes of secondary hypertension, but the comparative outcomes of targeted treatment remain unclear. Objective To compare the clinical outcomes in patients treated for primary al…
View article: Frequency of Screening for Colorectal Cancer by Predicted Life Expectancy Among Adults 76-85 Years
Frequency of Screening for Colorectal Cancer by Predicted Life Expectancy Among Adults 76-85 Years Open
This study assesses whether colorectal cancer screening varied by predicted life expectancy in a national sample of Veterans Affairs patients aged 76 to 85 years.
View article: Addressing the unique challenges in studies of long‐term medication use and dementia risk
Addressing the unique challenges in studies of long‐term medication use and dementia risk Open
This editorial comments on the article by Wu et al . in this issue.
View article: Improving Clinical Applicability of Mortality Prediction Models Among Persons With Dementia—Reply
Improving Clinical Applicability of Mortality Prediction Models Among Persons With Dementia—Reply Open
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View article: Systolic blood pressure, antihypertensive treatment, and cardiovascular and mortality risk in <scp>VA</scp> nursing home residents
Systolic blood pressure, antihypertensive treatment, and cardiovascular and mortality risk in <span>VA</span> nursing home residents Open
Background Optimal systolic BP (SBP) control in nursing home residents is uncertain, largely because this population has been excluded from clinical trials. We examined the association of SBP levels with the risk of cardiovascular (CV) eve…