H. S. Kim
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View article: Development of MMC-based lithium molybdate cryogenic calorimeters for AMoRE-II
Development of MMC-based lithium molybdate cryogenic calorimeters for AMoRE-II Open
The AMoRE collaboration searches for neutrinoless double beta decay of $$^{100}$$ Mo using molybdate scintillating crystals via low temperature thermal calorimetric detection. The early phases of the experiment, AMoRE-pilot and AMoRE-I,…
View article: Discovery of a Novel Multitarget Analgesic Through an In Vivo-Guided Approach
Discovery of a Novel Multitarget Analgesic Through an In Vivo-Guided Approach Open
Background: Pain is a complex condition influenced by peripheral, central, immune, and psychological factors. Multitarget approaches offer a more effective and safer alternative to single-target analgesics by enhancing efficacy, reducing s…
View article: Dual‐Cys bacteriophytochromes: intermediates in cyanobacterial phytochrome evolution?
Dual‐Cys bacteriophytochromes: intermediates in cyanobacterial phytochrome evolution? Open
Previous studies have identified three families of knotted phytochrome photoreceptors in cyanobacteria. We describe a fourth type: ‘hybrid’ phytochromes with putative bilin‐binding cysteine residues in both their N‐terminal ‘knot’ extensio…
View article: Using in vivo intact structure for system-wide quantitative analysis of changes in proteins
Using in vivo intact structure for system-wide quantitative analysis of changes in proteins Open
Mass spectrometry-based methods can provide a global expression profile and structural readout of proteins in complex systems. Preserving the in vivo conformation of proteins in their innate state is challenging during proteomic experiment…
View article: A protein–protein interaction analysis tool for targeted cross-linking mass spectrometry
A protein–protein interaction analysis tool for targeted cross-linking mass spectrometry Open
Protein networking is critical to understanding the biological functions of proteins and the underlying mechanisms of disease. However, identifying physical protein–protein interactions (PPIs) can be challenging. To gain insights into targ…
View article: PPIAT: Targeted Mass Spectrometry-Based Analysis Tool for Protein-Protein Interactions
PPIAT: Targeted Mass Spectrometry-Based Analysis Tool for Protein-Protein Interactions Open
Motivation: Protein networking is critical to understanding the biological functions of proteins and the underlying mechanisms of disease. However, identifying physical protein-protein interactions (PPIs) can be challenging. To gain insigh…
View article: Using In Vivo Intact Structure for System-wide Quantitative Analysis of Changes in Proteins
Using In Vivo Intact Structure for System-wide Quantitative Analysis of Changes in Proteins Open
Mass spectrometry-based methods can provide a global expression profile and structural readout of proteins in complex systems. Preserving the in vivo conformation of proteins in their innate state is challenging during proteomic experiment…
View article: <i>In vivo</i>Protein Footprinting Reveals the Dynamic Conformational Changes of Proteome of Multiple Tissues in Progressing Alzheimer’s Disease
<i>In vivo</i>Protein Footprinting Reveals the Dynamic Conformational Changes of Proteome of Multiple Tissues in Progressing Alzheimer’s Disease Open
Numerous studies have investigated changes in protein expression at the system level using proteomic mass spectrometry, but only recently have studies explored the structure of proteins at the proteome level. We developed covalent protein …
View article: PPIAT: Target Mass Spectrometry-based Protein-Protein Interaction Analytics Tool
PPIAT: Target Mass Spectrometry-based Protein-Protein Interaction Analytics Tool Open
Motivation The formation of protein networking is critical for understanding the biological functions of proteins and the underlying mechanisms of disease. To gain insights into target proteins that interact with a particular disease, we n…
View article: Status of the NEOS experiment
Status of the NEOS experiment Open
The NEOS experiment has successfully measured the reactor antineutrino energy spectrum at 24 m distance from Hanbit reactor unit 5 for 180 days of reactor operation and constrained the active-to-sterile oscillation parameters. An extended …
View article: Sterile neutrino search at the NEOS experiment
Sterile neutrino search at the NEOS experiment Open
In order to test the existence of the sterile neutrino, NEOS experiment was performed from August 2015 to May 2016. The prompt energy spectrum from the inverse beta decay of electron antineutrino from a 2.8 GW$_\mathrm{th}$ reactor was mea…
View article: NEOS Detector for Reactor Antineutrinos
NEOS Detector for Reactor Antineutrinos Open
NEOS intends to understand the short-distance behavior of reactor neutrino oscillation. The detector has been obtaining about 2,000 inverse beta decay (IBD) events on daily base, since its performance was stabilized in September 2015. We p…
View article: Development and Mass Production of a Mixture of LAB- and DIN-based Gadolinium-loaded Liquid Scintillator for the NEOS Short-baseline Neutrino Experiment
Development and Mass Production of a Mixture of LAB- and DIN-based Gadolinium-loaded Liquid Scintillator for the NEOS Short-baseline Neutrino Experiment Open
A new experiment, which is called as NEOS (NEutrino Oscillation at Short baseline), is proposed on the site of Hanbit reactors at Yonggwang, South Korea, to investigate a reactor antineutrino anomaly. A homogeneous NEOS detector having a 1…