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View article: Novel prognostic significance of the pectoralis muscle index in newly diagnosed multiple myeloma: A retrospective cohort study
Novel prognostic significance of the pectoralis muscle index in newly diagnosed multiple myeloma: A retrospective cohort study Open
Background Sarcopenia is common in multiple myeloma (MM) and may impact survival outcomes. The pectoralis muscle index (PMI), derived from chest CT, has shown prognostic relevance in various types of malignancies but has not been studied i…
View article: Sarcopenia attenuates the efficacy of PEGylated granulocyte colony-stimulating factor in preventing febrile neutropenia
Sarcopenia attenuates the efficacy of PEGylated granulocyte colony-stimulating factor in preventing febrile neutropenia Open
View article: Sarcopenia in Terminally Ill Patients with Cancer: Clinical Implications, Diagnostic Challenges, and Management Strategies
Sarcopenia in Terminally Ill Patients with Cancer: Clinical Implications, Diagnostic Challenges, and Management Strategies Open
Sarcopenia, characterized by progressive loss of skeletal muscle mass and strength, is a prevalent but often overlooked condition in patients with cancer who are terminally ill. It contributes to functional decline, increased symptom burde…
View article: Quality of life outcomes in terminal cancer patients attending regional cancer centers in South Korea: protocol for a prospective cohort study
Quality of life outcomes in terminal cancer patients attending regional cancer centers in South Korea: protocol for a prospective cohort study Open
KCT0009177 (registered at https//cris.nih.go.kr/ on 2024/02/16).
View article: Redefining YAP1 in small cell lung cancer: shifting from a dominant subtype marker to a favorable prognostic indicator
Redefining YAP1 in small cell lung cancer: shifting from a dominant subtype marker to a favorable prognostic indicator Open
Positive expression of YAP1 can be associated with durable CR and favorable survival outcomes in patients with SCLC, especially in LD.
View article: Efficacy of transdermal buprenorphine patch for managing withdrawal symptoms in patients with cancer physically dependent on prescription opioids
Efficacy of transdermal buprenorphine patch for managing withdrawal symptoms in patients with cancer physically dependent on prescription opioids Open
Background The physical dependence on prescription opioids among cancer survivors remains an under-investigated area, with a scarcity of well-designed prospective studies. Methods This single-arm, phase-2 clinical trial in Korea assessed t…
View article: Lipocalin‐2 as a prognostic biomarker and its association with systemic inflammation in small cell lung cancer
Lipocalin‐2 as a prognostic biomarker and its association with systemic inflammation in small cell lung cancer Open
Background Systemic inflammation is believed to contribute to small cell lung cancer (SCLC) progression, but the underlying relationship remains unclear. Lipocalin‐2, a potential biomarker of inflammation, has been implicated in various ca…
View article: Proportion of Non-Medical Opioid Use of Prescription Opioids among Cancer Patients in Korea
Proportion of Non-Medical Opioid Use of Prescription Opioids among Cancer Patients in Korea Open
This study found that 0.23% of cancer patients who had been prescribed opioids in Korea demonstrated NMOU. Despite this relatively low rate, careful monitoring is necessary to minimize the risk of NMOU in this population, especially among …
View article: Prognostic impact of pretreatment skeletal muscle index and CONUT score in diffuse large B-cell Lymphoma
Prognostic impact of pretreatment skeletal muscle index and CONUT score in diffuse large B-cell Lymphoma Open
View article: T/myeloid mixed-phenotype acute leukemia treated with venetoclax and decitabine: A case report
T/myeloid mixed-phenotype acute leukemia treated with venetoclax and decitabine: A case report Open
Fasting during the month of Ramadan is one of the five fundamental principles of Islam, and it is obligatory for healthy Muslim adults and adolescents. During the fasting month, Muslims usually have two meals a day, suhur (before dawn) and…
View article: Clinical implication of megestrol acetate in metastatic gastric cancer: A big data analysis from Health Insurance Review and Assessment (HIRA) database
Clinical implication of megestrol acetate in metastatic gastric cancer: A big data analysis from Health Insurance Review and Assessment (HIRA) database Open
Objective Megestrol acetate (MA) is used to manage anorexia and cachexia in patients with advanced cancer. This study investigated the prescription patterns of MA in patients with metastatic gastric cancer, as well as evaluated its impact …
View article: PB2678: THE PROGNOSTIC SIGNIFICANCE OF CONTROLLING NUTRITIONAL STATUS AND SARCOPENIA IN PATIENTS WITH DIFFUSE LARGE B-CELL LYMPHOMA
PB2678: THE PROGNOSTIC SIGNIFICANCE OF CONTROLLING NUTRITIONAL STATUS AND SARCOPENIA IN PATIENTS WITH DIFFUSE LARGE B-CELL LYMPHOMA Open
Topic: 35. Quality of life and palliative care Background: The Controlling Nutritional Status (CONUT) score has been shown to be a valuable prognostic index for diffuse large B-cell lymphoma (DLBCL) patients. However, it is unclear whether…
View article: Treatment of Opioid Withdrawal Syndrome Triggered by Oxycodone/Naloxone with Dexmedetomidine
Treatment of Opioid Withdrawal Syndrome Triggered by Oxycodone/Naloxone with Dexmedetomidine Open
The combination of oxycodone and naloxone is useful for cancer pain management. Naloxone, as a pure opioid antagonist, cannot be used simultaneously with opioids. However, owing to its low bioavailability, it can be used in an oral composi…
View article: The Korean Society for Neuro-Oncology (KSNO) Guideline for the Management of Brain Tumor Patients During the Crisis Period: A Consensus Survey About Specific Clinical Scenarios (Version 2023.1)
The Korean Society for Neuro-Oncology (KSNO) Guideline for the Management of Brain Tumor Patients During the Crisis Period: A Consensus Survey About Specific Clinical Scenarios (Version 2023.1) Open
It is imperative that proper medical care for brain tumor patients be sustained and provided, even during the crisis period. The findings of this consensus survey will be a useful reference in determining appropriate treatment options for …
View article: The Korean Society for Neuro-Oncology (KSNO) Guideline for the Management of Brain Tumor Patients During the Crisis Period: A Consensus Recommendation Using the Delphi Method (Version 2023.1)
The Korean Society for Neuro-Oncology (KSNO) Guideline for the Management of Brain Tumor Patients During the Crisis Period: A Consensus Recommendation Using the Delphi Method (Version 2023.1) Open
It is crucial that adequate medical care for patients with brain tumors is maintained and provided, even during times of crisis. This guideline will serve as a valuable resource, assisting in the delivery of treatment to brain tumor patien…
View article: The Endothelial Activation and Stress Index (EASIX) score is an independent prognostic factor in patients with diffuse large B-cell lymphoma
The Endothelial Activation and Stress Index (EASIX) score is an independent prognostic factor in patients with diffuse large B-cell lymphoma Open
View article: Clinical implication of megestrol acetate in advanced cancer: A big data analysis from Health Insurance Review and Assessment (HIRA) database
Clinical implication of megestrol acetate in advanced cancer: A big data analysis from Health Insurance Review and Assessment (HIRA) database Open
Purpose Megestrol acetate (MA) is used to manage anorexia and cachexia in patients with advanced cancer. This study investigated prescription patterns and impact on the survival and the venous thromboembolism (VTE) of MA in patients with a…
View article: The Endothelial Activation and Stress Index (EASIX) Score Is an Independent Prognostic Factor in Patients with Diffuse Large B-cell Lymphoma
The Endothelial Activation and Stress Index (EASIX) Score Is an Independent Prognostic Factor in Patients with Diffuse Large B-cell Lymphoma Open
Background: The endothelial activation and stress index (EASIX) score has been reported to predict overall survival (OS) in hematological cancers. However, it has not been validated as a prognostic marker for diffuse large B-cell lymphoma …
View article: Modified FOLFIRINOX as a Second-Line Treatment for Patients with Gemcitabine-Failed Advanced Biliary Tract Cancer: A Prospective Multicenter Phase II Study
Modified FOLFIRINOX as a Second-Line Treatment for Patients with Gemcitabine-Failed Advanced Biliary Tract Cancer: A Prospective Multicenter Phase II Study Open
Background: After the publication of the ABC-02 trial, gemcitabine and cisplatin combination therapy (GP) became the standard first-line treatment for advanced biliary tract cancer (BTC). Despite GP therapy, most patients suffer from disea…
View article: Cyclin D1 Serves as a Poor Prognostic Biomarker in Stage I Gastric Cancer
Cyclin D1 Serves as a Poor Prognostic Biomarker in Stage I Gastric Cancer Open
TNM stage still serves as the best prognostic marker in gastric cancer (GC). The next step is to find prognostic biomarkers that detect subgroups with different prognoses in the same TNM stage. In this study, the expression levels of epide…
View article: Diagnostic Value of Ascitic Tumor Markers for Gastric Cancer-associated Malignant Ascites
Diagnostic Value of Ascitic Tumor Markers for Gastric Cancer-associated Malignant Ascites Open
Background/Aims: Peritoneal carcinomatosis with malignant ascites is common in patients with advanced gastric cancer (GC). The detection of tumor cells is the gold standard for the diagnosis of malignant ascites; however, it often requires…
View article: Safe use of opioids
Safe use of opioids Open
Background: Opioids are effective analgesics for cancer pain and refractory non-cancer pain. Although they are essential medication, problematic issues on aberrant behavior and adverse events have rapidly emerged as social problems in Kore…
View article: Cachexia index as a potential biomarker for cancer cachexia and a prognostic indicator in diffuse large B‐cell lymphoma
Cachexia index as a potential biomarker for cancer cachexia and a prognostic indicator in diffuse large B‐cell lymphoma Open
Background Cancer cachexia is known to adversely affect the clinical course in patients with malignant lymphoma. The cachexia index (CXI) is a potential biomarker of cancer cachexia, and its implications for the prognosis and treatment out…
View article: Clinical significance of the cachexia index in patients with small cell lung cancer
Clinical significance of the cachexia index in patients with small cell lung cancer Open
Background Cancer cachexia worsens the treatment outcomes of patients with small-cell lung cancer (SCLC). However, no reliable biomarker of cancer cachexia is yet known. Methods We retrospectively evaluated male SCLC patients who received …
View article: Activated ERK Signaling Is One of the Major Hub Signals Related to the Acquisition of Radiotherapy-Resistant MDA-MB-231 Breast Cancer Cells
Activated ERK Signaling Is One of the Major Hub Signals Related to the Acquisition of Radiotherapy-Resistant MDA-MB-231 Breast Cancer Cells Open
Breast cancer is one of the major causes of deaths due to cancer, especially in women. The crucial barrier for breast cancer treatment is resistance to radiation therapy, one of the important local regional therapies. We previously establi…
View article: Apoptotic Effects of Anthocyanins from Vitis coignetiae Pulliat Are Enhanced by Augmented Enhancer of the Rudimentary Homolog (ERH) in Human Gastric Carcinoma MKN28 Cells
Apoptotic Effects of Anthocyanins from Vitis coignetiae Pulliat Are Enhanced by Augmented Enhancer of the Rudimentary Homolog (ERH) in Human Gastric Carcinoma MKN28 Cells Open
Evidence suggests that augmented expression of a certain gene can influence the efficacy of targeted and conventional chemotherapies. Here, we tested whether the high expression of enhancer of the rudimentary homolog (ERH), which serves as…
View article: Clinical significance of the cachexia index in patients with small-cell lung cancer
Clinical significance of the cachexia index in patients with small-cell lung cancer Open
Background: Cancer cachexia worsens the treatment outcomes of patients with small-cell lung cancer (SCLC). However, no reliable biomarker of cancer cachexia is yet known. Methods: We retrospectively evaluated SCLC patients who received ind…
View article: Prognostic model based on the geriatric nutritional risk index and sarcopenia in patients with diffuse large B-cell lymphoma
Prognostic model based on the geriatric nutritional risk index and sarcopenia in patients with diffuse large B-cell lymphoma Open
View article: Polyphenols Extracted from Artemisia annua L. Exhibit Anti-Cancer Effects on Radio-Resistant MDA-MB-231 Human Breast Cancer Cells by Suppressing Stem Cell Phenotype, β-Catenin, and MMP-9
Polyphenols Extracted from Artemisia annua L. Exhibit Anti-Cancer Effects on Radio-Resistant MDA-MB-231 Human Breast Cancer Cells by Suppressing Stem Cell Phenotype, β-Catenin, and MMP-9 Open
Artemisia annua L. has been reported to show anti-cancer activities. Here, we determined whether polyphenols extracted from Artemisia annua L. (pKAL) exhibit anti-cancer effects on radio-resistant MDA-MB-231 human breast cancer cells (RT-R…
View article: Prognostic model based on the Geriatric Nutritional Risk Index and sarcopenia in patients with diffuse large B-cell lymphoma
Prognostic model based on the Geriatric Nutritional Risk Index and sarcopenia in patients with diffuse large B-cell lymphoma Open
Background: Systemic inflammation and cachexia are associated with adverse clinical outcomes in diffuse large B-cell lymphoma (DLBCL). The Geriatric Nutritional Risk Index (GNRI) is one of the main parameters used to assess these condition…